🏃🏻♀️🍴CR, Metabolites, Protein homeostasis, Aging @UCBerkeley | @LeadingEdgeSymp '22; Prev: Fellow @downingcollege @Cambridge_Uni, @ForbesUnder30, @ETH_en
Berkeley, CA
Joined May 2014
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So excited and grateful to join this cohort of 2022 Leading Edge Fellows! Congratulations to all fellow early career researchers🎉 @LeadingEdgeSymp
Thanks to my wonderful mentors and advisors @Denis_V_Titov, @mvendruscolo14, Paola @Picotti_Lab for their support!
@UCBerkeley
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Priyanka Joshi (she/her) retweeted
Excited to share updated preprint by @ChoeMangyu showing that, contrary to textbook view, the role of allosteric regulation of glycolysis is not to control rate but to maintain ATP levels by preventing a futile cycle between upper and lower glycolysis. 🧵biorxiv.org/content/10.1101/…
Priyanka Joshi (she/her) retweeted
So, what’s new in our LiP-MS protocol for in situ #structural #proteomics?
- The new analysis package, MSStatsLiP, developed with @olgavitek 's group
- Improved robustness and throughput
- Lots of experimental design tips!
rdcu.be/c2aGS
#TeamMassSpec @NatureProtocols
Priyanka Joshi (she/her) retweeted
Molecular and environmental determinants of biomolecular condensate formation dlvr.it/SdM3GN
Priyanka Joshi (she/her) retweeted
I would say this is perhaps the most important paper in the amyloid field in the last 7 years. At least to me...
nature.com/articles/s41586-0…
Priyanka Joshi (she/her) retweeted
Why does Alzheimer's disease sweep through the brain in such a determined manner?
Why do amyloid aggregates form in certain brain regions and not others?
Why are some brain regions devastated and others spared?
Join our team & help us find out! jobso.id/fh3q
🙏RT
Priyanka Joshi (she/her) retweeted
It's been a tough week out there for layoffs- On the brighter side, there are many newcos excited to grow and hire.
Let me know if you're interested in joining a brand new biotech start up in the Bay Area with founders Micha Rapé, Aaron Gitler, and more. lyterian.com
Priyanka Joshi (she/her) retweeted
Join the next free @AggregateOA webinar. Develop your understanding of the fundamental process of protein folding and its roles in human diseases.
🔗: ow.ly/4m9m50LuHHh
Our expert speakers: @DannyHatters, @Picotti_Lab, @kfzhangxin, @VendruscoloLab, @BenZhongTANG1
Priyanka Joshi (she/her) retweeted
If you are doing proteomics combined with protein structure/prediction analysis please check out the vignette of our R package protti! Any feedback and suggestions are very welcome!
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Priyanka Joshi (she/her) retweeted
With the @Picotti_Lab we are hiring for a developer to set up a resource for protein dynamical information derived from proteomics data. Experience in web development and bioinformatics would be ideal. Long term perspective job with training opportunities jobs.ethz.ch/job/view/JOPG_e…
Priyanka Joshi (she/her) retweeted
Our work describing the modulation of co-translational protein folding by rational design and ribosome engineering was published by @NatureComms
nature.com/articles/s41467-0…
That was a long journey! Thank you! @MinkooAhn @AlkiMitropoulou and JC group:)
@uclbiosciences
Priyanka Joshi (she/her) retweeted
In Jan 2021, while having treatment for cervical cancer, I started filming myself. It started as a way to make sense of what was happening to me, but I soon realised there was a much bigger story, about how we approach cancer treatment in this country… telegraph.co.uk/health-fitne…
Really cool story 🔥- the cytoplasm is not “well-mixed” but represents a highly heterogeneous environment.
... demonstrates viscosity variation is independent of the cytoskeleton, cell cycle stage, and temperature – but increases under hyperosmotic shock.
Think the cytoplasm is well-mixed? Think again. In my latest work with @MolinesArthur and @fredchanglab we found the apparent viscosity of the cytoplasm may vary up to 100-fold (!) within individual cells, and 10-fold (!) between cells. A thread: (1/8) biorxiv.org/cgi/content/shor…
Priyanka Joshi (she/her) retweeted
Here is the link to Rob Phillips' 1st lecture @cdf1530
college-de-france.fr/site/th…
It introduces a view of quantitative biology, culminating in a definition of understanding that can answer the question of what sets the scale of sizes, time scales, concentrations, rates, energies etc
Priyanka Joshi (she/her) retweeted
I’ve collected several (currently 13) of the Jupyter notebooks I put together for teaching Cheminformatics in a Git repo and made them runnable on Google Colab. Hopefully, others will find the notebooks useful for teaching or self-study. github.com/PatWalters/practi…
Priyanka Joshi (she/her) retweeted
Beyond amyloid: Immune, cerebrovascular, and metabolic contributions to Alzheimer disease in people with Down syndrome: cell.com/neuron/fulltext/S08…
Priyanka Joshi (she/her) retweeted
Please RT: For those living in Paris, or willing to come and visit Paris for 1-2 days, here is an important announcement. Rob Phillips will give a series of 4 lectures at the Collège de France on Mondays 9, 16, 23 and 30 May. It's free, no registration needed. Just come and enjoy
Priyanka Joshi (she/her) retweeted
Small molecule modulation of protein polymerization - a Viewpoint from Eric Fischer and myself now published in Chemical Society Reviews pubs.rsc.org/en/content/arti…
Priyanka Joshi (she/her) retweeted
A bioinformatics web tool that enables the user to visualize, search and explore protein-ligand structural patterns within the entire Protein Data Bank.
GSP4PDB: a web tool to visualize, search and explore protein-ligand structural patterns
👇👇👇👇👇👇
bmcbioinformatics.biomedcent….
