@CellNinja

Assistant Professor at Washington University School of Medicine.

brookheartlab.wustl.edu
Joined April 2009
  • Tweets83
  • Following333
  • Followers175
Rita Brookheart retweeted
Erik Herzog@ErikHerzog4 Nov 2024
We worked hard to get polling stations on both @WUSTL campuses. @WashUdbbs and others who want to vote in STL city (students, faculty, staff, patients) please use the NEW polling station in McDonnell Building.
WashU@WashU4 Nov 2024
Tomorrow is #ElectionDay! The WashU Athletic Complex will welcome students, faculty, staff, and neighbors registered to vote in St. Louis County. For the first time, @washumedicine will also host a polling place for St. Louis City registered voters. bit.ly/3UCY4Qe
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Rita Brookheart retweeted
Andrew Judge@andyjudge2419 Jan 2023
Final program for the Advances in Skeletal Muscle Biology in Health & Disease Conference (Mar 15-17, 2023) is posted. Abstract deadline is Feb 8. Registration deadline is Feb 26. Hope to see you there! myology.institute.ufl.edu/wo…
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Rita Brookheart retweeted
Brian Finck@bnfinck25 Aug 2022
Based on an earlier observation made in a patient with an S1P mutation, this mechanistic work is starting to unravel some interesting roles for this protease in muscle metabolism. Glad to see this come to fruition and more interesting findings on the way!! – at O'Fallon, IL
Rita Brookheart@CellNinja25 Aug 2022
The first preprint from the Brookheart Lab identifies Site-1 Protease, a regulator of ATF6 and SREBPs, as an inhibitor of skeletal muscle metabolism and mass. Many thanks to our collaborators! @bnfinck @terri_pietka @lab_meyer biorxiv.org/content/10.1101/…

Site-1 Protease inhibits mitochondrial metabolism by controlling the TGF-β target gene MSS51

The mitochondrial response to changes in cellular energy demand is necessary for cellular adaptation and organ function. Many genes are essential in orchestrating this response, including the...

biorxiv.org
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Rita Brookheart retweeted
Brian Finck@bnfinck26 Apr 2022
Here's the latest from our lab. Truly a team effort involving three co-first authors @YiewNicole @MitoManny @Martino1440 who all sequentially made important contributions to this work. cell.com/cell-reports/fullte…

Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeog...

Martino et al. find that alanine transaminase 2 (ALT2), which is encoded by Gpt2, is increased in liver of mice and people with obesity by activating transcription factor 4. Suppression of Gpt2...

cell.com
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>5yrs ago as a #postdoc, @eteleeb and I began work on identifying #lncRNAs in late-stage relapse #breastcancer @ChrisMaher_Lab. Today, 🎉 #SilvaFisherlab @ChrisMaher_Lab paper highlighting some of our findings!! S/O @eteleeb hard work! 👏 nature.com/articles/s41523-0… (1/4)

LINC00355 regulates p27KIP expression by binding to MENIN to induce proliferation in late-stage...

npj Breast Cancer - LINC00355 regulates p27KIP expression by binding to MENIN to induce proliferation in late-stage relapse breast cancer

nature.com
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Great timing for the first day of #BlackHistoryMonth. Thank you @stlmag for this interview. Vaccine confidence, not vaccine hesitancy because the onus is upon us in medicine, in science, in public health and in government, to earn that trust of the communities we serve
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At number 4 in our countdown of the most viewed Reviews of 2021 is 'Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus', by @DanielF46305290 and @bnfinck (£) go.nature.com/3iM5tuq
Targeting of intermediary metabolism for NAFLD therapy

ALT Targeting of intermediary metabolism for NAFLD therapy

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I will be on PBS @NewsHour at 6pm CST with @IAmAmnaNawaz to discuss the current #COVID19 surge and the new CDC guidelines
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New Animal Virus Takes Northern Europe by Surprise scim.ag/wW29Pn
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