@eteleeb

Assistant Professor of Psychiatry at the Department of Psychiatry at Washington University School of Medicine in St. Louis

 St Louis, MO
Joined February 2011
  • Tweets76
  • Following66
  • Followers33
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Abdallah El-Thaileb, aka Eteleeb retweeted
medRxiv@medrxivpreprint2 Jan 2025
Transcriptomic analyses of human brains with Alzheimer disease identified dysregulated epilepsy-causing genes medrxiv.org/cgi/content/shor… #medRxiv
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Abdallah El-Thaileb, aka Eteleeb retweeted
PLOS Biology@PLOSBiology1 May 2024
Four types of #AlzheimersDisease? @eteleeb @B_A_Benitez @omharari &co use multiple #omics datasets & #MachineLearning to identify 4 distinct molecular profiles of #AD; one is associated with worse cognitive function & neuropathology #PLOSBiology plos.io/44E1FBv
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Excited to share that our latest paper on brain multi-#omics & molecular heterogeneity in #Alzheimers is in press today @PLOSBiology. We identified a multimodal profile with⬆️Braak tau, #synaptic, #endocytosis, #phagosome, & #mTOR pathways journals.plos.org/plosbiolog… @WUADRC

Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease

Omics studies have found molecular features associated with different clinical and pathological profiles in patients with Alzheimer’s disease. This study combines multiple high-throughput omics...

journals.plos.org
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Thanks to the many who supported this work @omharari @B_A_Benitez @karchlab @GusDavisLab @EricLenze2 @LexKravitz @WUADRC
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Abdallah El-Thaileb, aka Eteleeb retweeted
WashU Medicine Department of Medicine@WashUDeptMed11 Mar 2024
WashU Medicine rises to No. 2 in nation in NIH research funding @WUSTLmed is home to more than 1,000 NIH-funded projects and programs. Every $1 million in research funding creates 11 local jobs, drawing people to St. Louis and to WashU. Learn more > internalmedicine.wustl.edu/w…
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Abdallah El-Thaileb, aka Eteleeb retweeted
Celeste Karch@karchlab21 Sep 2023
Beyond excited to share our new story on the discovery that FTD tau mutations disrupt lncRNA SNHG8 which promotes stress granule formation. We think this is relevant to FTD, AD & PSP ⁦@RCFNeuro⁩ ⁦@CurePSP⁩ ⁦⁦@AFTDHope⁩ ⁦ nature.com/articles/s41380-0…

Long non-coding RNA SNHG8 drives stress granule formation in tauopathies

Molecular Psychiatry - Long non-coding RNA SNHG8 drives stress granule formation in tauopathies

nature.com
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Excited to receive the NOA for my K25 from @NIHAging and to continue my research on cross-omics integration in Alzheimer’s disease. Huge thanks to the many people who supported my application!! @omharari, @karchlab, @EricLenze2, @adamqbauer, @GusDavisLab, @ChrisMaher_Lab, @WUADRC
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Excited to share that my K25 application received an excellent fundable score. Can't wait to see this moving forward for funding @WUADRC
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Abdallah El-Thaileb, aka Eteleeb retweeted
Celeste Karch@karchlab14 Jun 2022
Excited to share a new pre-print from the lab led by ⁦@miguel_minaya_⁩ @CurePSP @AFTDHope ⁦@WUADRC⁩ @WUSTLnews @WashUGenetics @WashUONR @WashUNeurology @RCFNeuro ⁦@cziscience⁩ 🧠🧫🧬🧪 medrxiv.org/content/10.1101/…

Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling

More than 50 mutations in the MAPT gene result in heterogeneous forms of frontotemporal lobar dementia with tau inclusions (FTLD-tau). However, early pathogenic events that lead to disease and the...

medrxiv.org
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Abdallah El-Thaileb, aka Eteleeb retweeted
Nikolay Oskolkov@NikolayOskolkov4 Jun 2022
I just published at Medium / Towards Data Science @TDataScience Why PCA Looks Triangular towardsdatascience.com/why-p…
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Abdallah El-Thaileb, aka Eteleeb retweeted
Alex Ritter, PhD@AlexRitterPhD14 Apr 2022
Small but mighty! This is a video of a killer T cell of the immune system destroying a monstrous ovarian cancer cell. I recently captured this data on a spinning disc confocal microscope.
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Abdallah El-Thaileb, aka Eteleeb retweeted
Dr. Jess Silva-Fisher@JessSFisher13 Apr 2022
>5yrs ago as a #postdoc, @eteleeb and I began work on identifying #lncRNAs in late-stage relapse #breastcancer @ChrisMaher_Lab. Today, 🎉 #SilvaFisherlab @ChrisMaher_Lab paper highlighting some of our findings!! S/O @eteleeb hard work! 👏 nature.com/articles/s41523-0… (1/4)

LINC00355 regulates p27KIP expression by binding to MENIN to induce proliferation in late-stage...

npj Breast Cancer - LINC00355 regulates p27KIP expression by binding to MENIN to induce proliferation in late-stage relapse breast cancer

nature.com
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Abdallah El-Thaileb, aka Eteleeb retweeted
Celeste Karch@karchlab1 Feb 2022
Congratulations to @eteleeb on your recent promotion and for being named a Knight ADRC REC Scholar! @WUADRC @Neuro_Genomics
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Abdallah El-Thaileb, aka Eteleeb retweeted
NeuroGenomics and Informatics Center@Neuro_Genomics1 Feb 2022
Congratulations @miguel_minaya_ from @karchlab and @eteleeb from @omharari lab on being named Kight ADRC REC scholars!! @WUADRC
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sciencedirect.com/science/ar…
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Check out our recent publication on the detection of structural variants hotspots. nature.com/articles/s41598-0…

SV-HotSpot: detection and visualization of hotspots targeted by structural variants associated with...

Scientific Reports - SV-HotSpot: detection and visualization of hotspots targeted by structural variants associated with gene expression

nature.com
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Abdallah El-Thaileb, aka Eteleeb retweeted
Chris Miller@chrisamiller31 Oct 2018
New paper out today! A quick explainer: nejm.org/doi/full/10.1056/NE… Cancer immunotherapy is thought of as new, but bone marrow transplants have been around for decades. These can suppress leukemia, but long-term survival still is poor - most ultimately relapse post allo transplant

Immune Escape of Relapsed AML Cells after Allogeneic Transplantation | NEJM

As consolidation therapy for acute myeloid leukemia (AML), allogeneic hematopoietic stem-cell transplantation provides a benefit in part by means of an immune-mediated graft-versus-leukemia effect....

nejm.org
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Abdallah El-Thaileb, aka Eteleeb retweeted
Lior Pachter@lpachter2 Dec 2017
Please stop using Tophat scholar.google.com.mx/schola… Cole and I developed the method in *2008*. It was greatly improved in TopHat2 then HISAT & HISAT2. There is no reason to use it anymore. I have been saying this for years yet it has more citations this year than last #methodsmatter
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Washington University receives $10 million for DNA sequencing research ow.ly/70um30cXvfM via @stlouisbiz
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