@BuddleJess

PhD student @sheffielduni in @RobFagan lab, looking at vancomycin resistance in C. difficile 🦠 | Lover of pizza, cake and labradors 🐕

 West Yorkshire
linkedin.com/in/jessicabuddle
Joined October 2019
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✨️ It's been a long time coming ✨️ journals.plos.org/plosbiolog… Really excited to finally be able to share the publication of my first first-author research paper in PLOS Biology today! A Thread 🧵

Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that...

Clostridioides difficile is a human pathogen primarily treated with the antibiotic vancomycin. High-level vancomycin resistance is a serious problem in other pathogens, not yet for C. difficile. This...

journals.plos.org
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We have 2 fully funded PhD studentships available through the new Yorkshire Biosciences DTP (starting Oct 25) - please share! Both projects are focussed on #phage that infect #Cdifficile
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Happy to say I passed my PhD viva yesterday! Im so grateful for the most amazing 4 years. Special thanks to @RobFagan and Mike Brockhurst, the lab, and everyone who made the last 4 years so fantastic. Thanks also to my examiners @SmitsLab and @corrigar1 for a great viva! #PhDone
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Jess Buddle retweeted
Cyril@Cyril_Anjou18 Sep 2024
The second chapter of my PhD is out! We are bringing new elements for the potential use oof auranofin as a Clostridioides difficile treatment nature.com/articles/s41522-0…

Adaptation mechanisms of Clostridioides difficile to auranofin and its impact on human gut microb...

npj Biofilms and Microbiomes - Adaptation mechanisms of Clostridioides difficile to auranofin and its impact on human gut microbiota

nature.com
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#Cdifficile is mainly treated with #vancomycin, so why is resistance not yet a problem? @BuddleJess @BrockhurstLab @RobFagan &co identify 2 resistance pathways that evolve rapidly but with fitness costs that could affect transmission #AMR #PLOSBiology plos.io/3YNHS1m
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Nothing says "made it" like sharing a newspaper page in the @DailyMirror with @taylorswift13 😭🥳🤩
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Researchers @BuddleJess, @RobFagan and team have discovered how the hospital superbug C.diff rapidly evolves resistance to the frontline drug used for treatment in the UK. Read Rob's thread to find out more about the study 👇
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Replying to @BuddleJess @RobFagan @LucyThmpsn @asw_stafford @RoyChaudhuri
🧵15 If you got to the end of this mammoth post and dont want to scroll back up, the paper is here 😉 journals.plos.org/plosbiolog…

Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that...

Clostridioides difficile is a human pathogen primarily treated with the antibiotic vancomycin. High-level vancomycin resistance is a serious problem in other pathogens, not yet for C. difficile. This...

journals.plos.org
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🧵16 A final note to say (first) thanks for reading! And (second) i am #opentowork - looking for roles in the life sciences sphere. Grateful for any reposts, connections and advice :)
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