@RobFagan
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We are the Clostridial Cell Biology Group at the University of Sheffield @sheffielduni @MM_Sheffield Clostridial cell biology & phage structure and function.
Sheffield
Joined December 2010
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Fagan Lab at the University of Sheffield retweeted
New paper alert! A toolbox of genetic tools for use in Clostridia, made available to the community. @MicrobioSoc @RobFagan microbiologyresearch.org/con…
Fagan Lab at the University of Sheffield retweeted
🚨 Fully funded PhD studentships 🚨 We have 3 fully funded PhD studentships available for Oct 26 start. Funded by the MRC DiMeN programme & the BBSRC Yorkshire Biosciences DTP. Details below as they are advertised. Contact me here or via email for more details or to discuss
🚨 Fully funded PhD studentships 🚨 We have 3 fully funded PhD studentships available for Oct 26 start. Funded by the MRC DiMeN programme & the BBSRC Yorkshire Biosciences DTP. Details below as they are advertised. Contact me here or via email for more details or to discuss
Project 2: Doubling down: determining the dual function of VanT in C. difficile antibiotic resistance.
findaphd.com/phds/project/mr…
Project 3: Predicting pathogen evolution: using experimental evolution to understand the impact of phage therapy on Clostridioides difficile.
findaphd.com/phds/project/bb…
The 2025 round of the MSCA Postdoc Fellowships launches soon, with a deadline of September 10th. If you're interested in Clostridial cell biology and looking for a host lab for your fellowship please get in touch to discuss possible projects
ALT https://sites.google.com/sheffield.ac.uk/fagan-lab/
The Marie Skłodowska-Curie Actions Fellowships support applicants up to 8 years post-PhD from anywhere in the world who want to spend 1-2 years working in Europe (incl. UK!). These can be a fantastic stepping stone to longer term fellowships and establishing independence
More info on the MSCA schemes here:
marie-sklodowska-curie-actio…
and you can see a few of our current projects here:
sites.google.com/sheffield.a…
New paper alert 🚨 We've solved the complete structure of a C. difficile-infecting phage using cryo-EM, in both extended and contracted conformations - published today in Life Science Alliance
Interestingly the tail contracts less than in other characterised phages (& related contractile structures). This seems to be a feature of phage infecting bacteria that have an S-layer - given that these are likely the majority of bacteria, this is probably really common
The 2nd round of our Yorkshire Biosciences PhD programme is now open for applications - deadline March 14th. Both of our C. diff phage projects are also available in this round - details in the thread below.
More info and expressions of interest here:
app.onlinesurveys.jisc.ac.uk…
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Fagan Lab at the University of Sheffield retweeted
No2...Predicting pathogen evolution: using experimental evolution to understand the impact of phage therapy on Clostridioides difficile with @RobFagan tinyurl.com/22vzvb27 #microbialevolution #pathogenevolution #PhDposition
Fagan Lab at the University of Sheffield retweeted
PhDs avaliable in the lab! No1....what are rhizobia up to OUTSIDE the symbiosis? tinyurl.com/8mybvaha with Prof Tim Daniell. Come along to our project info session Tues 10th at 2pm. register here tinyurl.com/y76au57n #microbialevolution #symbiosis #PhDposition
We have 2 fully funded PhD studentships available through the new Yorkshire Biosciences DTP (starting Oct 25) - please share! Both projects are focussed on #phage that infect #Cdifficile
Project 1: Led by @ellieevolves, we will study the evolutionary interplay between #Cdiff and #phage and impact of sporulation on this relationship.
findaphd.com/phds/project/pr…
Project 2: Led by Per Bullough and in collaboration with @Sheffield_AFM we will study the structural basis of #phage infection of #Cdiff cells at unprecedented resolution. #cryoEM #AFM
findaphd.com/phds/project/me…
