We are the Balko Research Lab at VUMC, a translational cancer research lab at the interface of tumor biology and immunotherapy. Opinions RR own.
Nashville, TN
Joined February 2019
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New from our lab in @ScienceTM: Peripheral blood transcriptional profiling predicts breast cancer tumor subtype and response to neoadjuvant chemoimmunotherapy.
This blood-based RNA sig achieves strong predictive performance, offering a non-invasive way to stratify patients, optimize therapy selection, and avoid unnecessary toxicity. science.org/doi/10.1126/scit…
Huge congrats to the team!
#BreastCancer #Immunotherapy #PrecisionMedicine
BalkoResearchLab retweeted
This was a collaborative effort across multiple institutions! A huge shout out to my twitterless co-first author Alan Gutierrez and my PI @CardioOncology, along with all co-authors and funding sources. @Pan_Ma_ @ScientistBaylis @LavineLab @BalkoLab @SarnoffCardio @czbiohub
BalkoResearchLab retweeted
New #JITC article: Monitoring systemic immune responses to checkpoint inhibition in breast cancer reveals host responses and mechanisms of resistance jitc.bmj.com/content/13/12/e…
@BCT255 @BalkoLab
BalkoResearchLab retweeted
New study 👉Dynamic single-cell systemic immune responses in immunotherapy-treated early-stage HR+ #BreastCancer patients.
🔓 pubmed.ncbi.nlm.nih.gov/4061…
@MargaretAxelrod @stolaney1 @EMittendorfMD @BalkoLab
Looks amazing! Great work @ECBrunner!
Check out this article that made the 2025 cover of Cancer Research Communications:
Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer brnw.ch/21wQki5 @BalkoLab
BalkoResearchLab retweeted
State of the Art: The Winding Road of Immune Biomarkers in Early Breast Cancer—Roberto Salgado, Justin Balko, and Priyanka Sharma will address this topic in this special session at #SABCS24 (December 10-13). Learn more:
bit.ly/3BjXxfB
@BalkoLab @psharmalab
BalkoResearchLab retweeted
State of the Art: The Winding Road of Immune Biomarkers in Early Breast Cancer—
Roberto Salgado, Justin Balko, and Priyanka Sharma will address this topic in this special session at #SABCS24 (December 10-13). Learn more:
bit.ly/4h3tAR0
@BalkoLab @psharmalab
BalkoResearchLab retweeted
Next, @MargaretAxelrod talks about patient and tumor specific biomarkers in ici myocarditis👌 #gcos #gcos24 @ICOSociety @BalkoLab @CardioOncology
BalkoResearchLab retweeted
As we better understand mechanisms that may drive ICI-myocarditis, we can think of more targeted therapies! Work by many individuals including @DrJESalem @JimAllisonPhD @CardioOncology @BalkoLab have led to ideas of targeting CD80/86, JAK-STAT signaling pathways, and T-cells!
6/
BalkoResearchLab retweeted
Meet Immuno-oncology Senior Editor Justin M. Balko, PharmD, PhD. The @BalkoLab is focused on improving treatment outcomes in BC & other solid tumors, as well as the intersection between immunotherapy and tumor biology. Read the latest articles:
bit.ly/3Lajnn3
BalkoResearchLab retweeted
#ASCO24 Poster Session | Analysis of the sensitivity to endocrine therapy assay in the PALLAS adjuvant trial of palbociclib in HR+/HER2- #breastcancer (ABCSG-42/AFT-05/BIG-14-13).
@Otto_DFCI @elmayermd @MichaelGnant @AngieDemichele @ChristinaCurtis @cncurtis @BalkoLab
BalkoResearchLab retweeted
Komen grantee @BalkoLab presents his work on understanding and improving #breastcancer response to immunotherapy @ #AACR24. To learn more, check out the MBC Impact Series where he discussed his work: bit.ly/4cFtpsN
So proud of this outstanding scientist and person @BCT255 defending her thesis today. A @SusanGKomen ASPIRE scholar, @CD_AACR @jitcancer published author and all around superstar. Can't wait to see what the future holds!! @VUMCResearch @VUBasicSciences
BalkoResearchLab retweeted
This line up!!! Phenomenal. @sitcancer Spring Scientific. Happening NOW! – at Florida, USA
Look at that lineup! So excited to co-organize (@JennGuerriero @JenWargoMD) the @sitcancer Spring Scientific #SprITC2024 focused on metabolism in cancer immunotherapy! Hope you can join us!
BalkoResearchLab retweeted
I am defending my dissertation next week on March 15th! Grateful for the mentorship by @BalkoLab !
DM me if you would like the zoom link.
BalkoResearchLab retweeted
Rock.Star. Great talk with wonderful implications for the next generation of myeloid therapy in ccRCC. Can’t wait to see what you do next! – at Los Angeles, CA
Congratulations to newly minted Dr. @melissa_m_wolf ! Co-mentored with @KimrynRathmell in @VUMC_Cancer, we're proud of what you've done and excited for the next steps!
BalkoResearchLab retweeted
From the latest issue—
#NKG2A is a Therapeutic Vulnerability in #Immunotherapy Resistant MHC-I Heterogeneous Triple Negative #BreastCancer, by @BCT255, @SXPung, @BalkoLab et al.
bit.ly/49WMp43
@VUMCDiscoveries #TNBC
Super excited for next year's meeting! Only 290 days and counting (OK you got me... I didn't do the math I just guessed 😂)
We thank our program committee for creating a great #SABCS24 lineup.
@VKaklamani @CarlosArteagaMD @BalkoLab @tperrybrown @heide_ford @HarrisLabUTHSA @TariKingMD @lab_kok @Adrianvlee @itsnot_pink @hmcarthur @dapattmd @c_sotiriou @atanmdlci @NeilVasan @adawaksmd @awolff @AACR_CEO
Excited to see the *official* version out!!! Great job by the editorial staff... It looks phenomenonal!
From the February issue—
#NKG2A is a Therapeutic Vulnerability in #Immunotherapy Resistant MHC-I Heterogeneous Triple Negative #BreastCancer, by @BCT255, @SXPung, @BalkoLab et al.
bit.ly/49CFb4U
@VUMCDiscoveries #TNBC
