We are the Balko Research Lab at VUMC, a translational cancer research lab at the interface of tumor biology and immunotherapy. Opinions RR own.
Nashville, TN
Joined February 2019
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BalkoResearchLab retweeted
This was a collaborative effort across multiple institutions! A huge shout out to my twitterless co-first author Alan Gutierrez and my PI @CardioOncology, along with all co-authors and funding sources. @Pan_Ma_ @ScientistBaylis @LavineLab @BalkoLab @SarnoffCardio @czbiohub
BalkoResearchLab retweeted
New #JITC article: Monitoring systemic immune responses to checkpoint inhibition in breast cancer reveals host responses and mechanisms of resistance jitc.bmj.com/content/13/12/e…
@BCT255 @BalkoLab
BalkoResearchLab retweeted
New study 👉Dynamic single-cell systemic immune responses in immunotherapy-treated early-stage HR+ #BreastCancer patients.
🔓 pubmed.ncbi.nlm.nih.gov/4061…
@MargaretAxelrod @stolaney1 @EMittendorfMD @BalkoLab
BalkoResearchLab retweeted
State of the Art: The Winding Road of Immune Biomarkers in Early Breast Cancer—Roberto Salgado, Justin Balko, and Priyanka Sharma will address this topic in this special session at #SABCS24 (December 10-13). Learn more:
bit.ly/3BjXxfB
@BalkoLab @psharmalab
BalkoResearchLab retweeted
State of the Art: The Winding Road of Immune Biomarkers in Early Breast Cancer—
Roberto Salgado, Justin Balko, and Priyanka Sharma will address this topic in this special session at #SABCS24 (December 10-13). Learn more:
bit.ly/4h3tAR0
@BalkoLab @psharmalab
BalkoResearchLab retweeted
Next, @MargaretAxelrod talks about patient and tumor specific biomarkers in ici myocarditis👌 #gcos #gcos24 @ICOSociety @BalkoLab @CardioOncology
BalkoResearchLab retweeted
As we better understand mechanisms that may drive ICI-myocarditis, we can think of more targeted therapies! Work by many individuals including @DrJESalem @JimAllisonPhD @CardioOncology @BalkoLab have led to ideas of targeting CD80/86, JAK-STAT signaling pathways, and T-cells!
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BalkoResearchLab retweeted
Meet Immuno-oncology Senior Editor Justin M. Balko, PharmD, PhD. The @BalkoLab is focused on improving treatment outcomes in BC & other solid tumors, as well as the intersection between immunotherapy and tumor biology. Read the latest articles:
bit.ly/3Lajnn3
BalkoResearchLab retweeted
#ASCO24 Poster Session | Analysis of the sensitivity to endocrine therapy assay in the PALLAS adjuvant trial of palbociclib in HR+/HER2- #breastcancer (ABCSG-42/AFT-05/BIG-14-13).
@Otto_DFCI @elmayermd @MichaelGnant @AngieDemichele @ChristinaCurtis @cncurtis @BalkoLab
BalkoResearchLab retweeted
Komen grantee @BalkoLab presents his work on understanding and improving #breastcancer response to immunotherapy @ #AACR24. To learn more, check out the MBC Impact Series where he discussed his work: bit.ly/4cFtpsN
BalkoResearchLab retweeted
This line up!!! Phenomenal. @sitcancer Spring Scientific. Happening NOW! – at Florida, USA
Look at that lineup! So excited to co-organize (@JennGuerriero @JenWargoMD) the @sitcancer Spring Scientific #SprITC2024 focused on metabolism in cancer immunotherapy! Hope you can join us!
BalkoResearchLab retweeted
I am defending my dissertation next week on March 15th! Grateful for the mentorship by @BalkoLab !
DM me if you would like the zoom link.
BalkoResearchLab retweeted
Rock.Star. Great talk with wonderful implications for the next generation of myeloid therapy in ccRCC. Can’t wait to see what you do next! – at Los Angeles, CA
Congratulations to newly minted Dr. @melissa_m_wolf ! Co-mentored with @KimrynRathmell in @VUMC_Cancer, we're proud of what you've done and excited for the next steps!
BalkoResearchLab retweeted
From the latest issue—
#NKG2A is a Therapeutic Vulnerability in #Immunotherapy Resistant MHC-I Heterogeneous Triple Negative #BreastCancer, by @BCT255, @SXPung, @BalkoLab et al.
bit.ly/49WMp43
@VUMCDiscoveries #TNBC
BalkoResearchLab retweeted
Proud to present this pre-print from my lab. Using single-cell multi-omics, 2 mice models, & pt samples, we found CXCR3 as a novel therapeutic target for ICI myocarditis critical for T-cell/macrophage crosstalk and perpetuation of cardiac inflammation biorxiv.org/content/10.1101/…
BalkoResearchLab retweeted
Tune in NOW for Breast Cancer Breakthroughs! Hear about the most exciting wins for patients announced at #SABCS23 from Komen grantees. Click here to watch: bit.ly/3X1yPW0
BalkoResearchLab retweeted
A recent paper from the @balkolab, led by Jamaal James and @bct255, indicates that EZH2 inhibition leads to enhanced MHC-II expression potentially through the improvement of chromatin accessibility at CIITA, the master regulator of MHC-II.
doi.org/10.1136/jitc-2023-00…
BalkoResearchLab retweeted
Congrats @paspears88 on such a well deserved award! 2023 Komen Research Advocacy Champion Award! @UNC_Lineberger #SABCS23 @SusanGKomen 👏👏
BalkoResearchLab retweeted
Let’s take a closer look at “Polycomb repressor complex 2 suppresses interferon-responsive MHC-II expression in melanoma cells and is associated with anti-PD-1 resistance” by @BCT255 @BalkoLab at @VUBasicScience @VUMCDiscoveries 1/9
