Pediatric Rheumatologist, MD, PhD, Lyon, France

Joined January 2020
Genetic clues explain why children develop a rare post-COVID condition. @SanchoShimizu and researchers from our @ImperialInfect and @TheCrick have uncovered genetic variants which help explain why some children developed MIS-C after having COVID-19. imperial.ac.uk/news/258534/g…
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IFNopathies: Des guidelines très utiles par une équipe pluridisciplinaire. Merci à tous !
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With @FHaerynck & Dan Kastner and many new / unpublished works from talented Post doc, phD student and seniors
Journée rhumatopédies le 4 décembre prochain, n'hésitez pas à vous inscrire en suivant le lien ci-dessous! @HCL_research
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‘Human Peoples’ is out @PenguinBooks A genetic journey through how migrations, admixture (among humans and with Neanderthals and Denisovans), and adaptations to environmental pressures (climate, nutrition, pathogens) shaped our physiology and health today. amazon.co.uk/Human-Peoples-E…
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Belot Alexandre retweeted
📢Reminder to register for the next Lunch with RITA webinar! 🗓️ 5 Nov 2024 ⏰ 12:00 CET 💬 Topic: Granulomas in PID & Immune Dysregulation 🎙️ Speakers: Dr. Benjamin Fournier & Dr. Carine Wouters Don’t miss insights on key treatment strategies! 🔗Register: lnkd.in/edeD8ADC
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Part of the fascinating world of JAK-STATopathies!
.@JEANPIERRMarie, @CgdJade, @AlexandreBelot et al suggest that PTPN2 along w/ SOCS1 haploinsufficiency constitute a new group of monogenic autoimmune diseases that can benefit from targeted therapy hubs.la/Q02TfHw40 📘In our #Autoimmunity collection: hubs.la/Q02Tfw890
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🗣️Excited to share our paper defining a standard dataset for cSLE registry research! 🩺Our team developed a core dataset to harmonize cSLE data collection and promote international collaboration to advance cSLE research! ard.bmj.com/content/annrheum… @evemdsmith_eve @AlexandreBelot
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Belot Alexandre retweeted
🌟Join us for our next Tuesday Lunch with RITA webinar on October 1! Topic: "Histiocytosis and Inflammation: How I Manage H Syndrome." 🗓️ 12:00 - 13:00 CEST Panelists: Dr. Maurine Jouret & Dr. Julien Haroche Chair: Dr. @AlexandreBelot 🔗 Register: register.gotowebinar.com/reg…
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Une chance pour l'HFME et les enfants malades pour le bien-être de nos jeunes patients et la promotion de leur activité physique. @HCL_research, @CHUdeLyon. Un grand merci @OLfondation, Maelle & Christophe et félicitations aux nouveaux venus au CA @WRenard @GovouSidney !
Le Conseil d'Administration de la Fondation OL s'est réuni en ce début de saison 2024/2025. Deux renforts majeurs ont rejoint le Conseil : @WRenard et @GovouSidney ! 🔴🔵 Découvrez les nouveaux projets : ol.fr/fr/actualites/fondatio…
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Félicitations ML ! Ce n'est qu'une étape, le meilleur à venir ! bravo 👏👏👏 c'est bien mérité
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Delighted to host @HsiehElena for a great talk on how to explore renal biopsies of #lupusnephritis with multi-omics including spatial transcriptomics. @CIRI_Lyon @lyacts @HCL_research
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Proud of you Jade @CgdJade for winning first prize for your basic/translational research abstract on PTPN2-HA! 🎉 @FRLab1 @lyacts Congrats to all presenters for an excellent #PRES2024 congress! See U next year
Congratulations to all the winners of the best abstracts award at the #PReS2024 Young Investigators Meeting
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The upcoming rheumatopedies meeting coming soon: great speakers and exciting research from masters , PhD student and researchers with guest speakers @FHaerynck & Dan Kastner !
📢 SAVE THE DATE! RHUMATOPEDIES 2024 is coming 📅Wednesday 4th December 2024 📌 University of Lyon, 69007 LYON 👨‍⚕️ Lecture by Prof. Daniel Kastner, MD, PhD 📝 Registration: lnkd.in/emX8Pn8T 📰 Scientific Programme below
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Fantastic findings, very elegant! Well done Petter and Co. 👏👏
New paper out @Nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones? Here we studied adaptation of human immune systems to gender-affirming testosterone treatment in trans-men assigned female sex at birth: nature.com/articles/s41586-0…
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Incredible discovery. Also very informative for users of TNFa blockers!
The latest paper of our lab, led by first class first authors @ALNeehus and @AriasAAS !
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Findings from @JEANPIERRMarie, @CgdJade, @FRLab1, @AlexandreBelot et al. suggest that PTPN2 along with SOCS1 haploinsufficiency constitute a new group of monogenic autoimmune diseases that can benefit from targeted therapy. hubs.la/Q02Hvg8z0 #lupus #autoimmunity
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PTPN2 deficiency: Amping up JAK/STAT. Joshua Tobin and Megan Cooper @MACattackLab @WUSTLmed discuss study from Marie Jeanpierre, Jade Cognard, @FRLab1, @AlexandreBelot, Mathieu and colleagues (hubs.la/Q02HrXdq0): hubs.la/Q02HrFLB0
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Haploinsufficiency in PTPN2 leads to early-onset systemic #autoimmunity from Evans syndrome to #lupus, say Marie Jeanpierre (@JEANPIERRMarie), Jade Cognard (@CgdJade), Frédéric Rieux-Laucat @FRLab1, @AlexandreBelot, Anne-Laure Mathieu & colleagues hubs.la/Q02HvkMP0
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Belot Alexandre retweeted
6 novel monoallelic PTPN2 mutations in pediatric lupus and Evans syndrome that cause T cell hyperproliferation and high inflammatory cytokines @JExpMed doi.org/10.1084/jem.20240980 @MACattackLab comment doi.org/10.1084/jem.20232337 @AlexandreBelot @FRLab1 #Mathieu
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