Developmental biologist working on cell and tissue mechanics. Have been and continue to be stuck on those 10 most important min of life in Drosophila.
Joined May 2021
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How is robustness ensured when tissues push/pull one another during morphogenesis? Dedicated programs are needed and they diverged and emerged abruptly due likely to mechanics driven positive feedback.
How do embryos avoid inter-tissue mechanical conflicts? Check out our preprint on the cephalic furrow: doi.org/10.1101/2023.10.09.5…
An awesome collaboration between @yuchiunwang Lab @BDR_RIKEN, and the Lemke lab @COSHeidelberg lead by @bipashadey29, @girish_kale_phd, and myself. A 🧵
Yu-Chiun Wang retweeted
Congratulations, Anna Erzberger!
The EMBL Group Leader has received the Inaugural Suzanne Eaton ‘Rising Star’ Award for Physics of Life in 2026, presented by @PoLDresden.
Learn more: embl.org/news/awards-honours…
Yu-Chiun Wang retweeted
新しい論文 出ました。
Our paper is now online!
How can we describe active agents—filaments and cells—on curved surfaces? How does curvature affect their collective behavior?
We develop a simple geometric framework and show that flocking depends on curvature heterogeneity. doi.org/10.1103/mxgg-9w4l
Yu-Chiun Wang retweeted
I found that my master’s research on Coupled Map Gas(hdl.handle.net/2433/95929) is featured in a recent review (doi.org/10.1016/j.physrep.20…). I published it much later (doi.org/10.1016/S0167-2789(0…). My supervisor @KsqU_LL had always encouraged me to publish it. Here, a supplementary movie.
Yu-Chiun Wang retweeted
Tissue patterning is essential to development. Now it is shown that boundary cues can drive the patterning of embryonic tissue.
nature.com/articles/s41567-0…
Yu-Chiun Wang retweeted
Pleased to share our study on brachiopods and dorsal–ventral patterning, now out in @NatureComms.
doi.org/10.1038/s41467-026-7…
We present the first chromosome-level genome of a brachiopod and show that the core patterning mechanism is deeply conserved across bilaterians.
(1/5)
Yu-Chiun Wang retweeted
New preprint: How is multicellular handedness determined? The same cell chirality can produce opposite multicellular handedness. Just as a car move forward or backward from the same engine rotation. By @TomokiIshibashi, et al. doi.org/10.64898/2026.04.04.…
Yu-Chiun Wang retweeted
🧐Dive into BDR's Intriguing Research with Tomoki Ishibashi, Special Postdoctoral Researcher in the Lab for Physical Biology.
Learn about his interest in left-right asymmetry, his current research and future aspirations.
bdr.riken.jp/en/bdrtimes/202…
Yu-Chiun Wang retweeted
理研BDRで進行中のアツい研究をしている研究者から研究者へとバトンを繋ぐインタビュー。今回は石橋朋樹さんにネホリハホリしてきました！タイトルは「左右非対称から始まるロマンの話」です✨
⚙️左右非対称のロマン
⚙️回る細胞の謎
⚙️物理と生物の間の学問
👇記事はこちらbdr.riken.jp/ja/bdrtimes/202…
Yu-Chiun Wang retweeted
I’m so happy to have been part of such a fruitful and, above all, FUN collaboration! Physics and biology come together to help us understand the fundamental mechanisms of embryonic development. There’ll be more news soon, so stay tuned 👀
Our paper is out in Nature Physics🎉 We uncovered how mouse epiblast cells acquire orientational order guided by tissue boundaries, combining 3D quantitative imaging with theory. A wonderful collaboration with @ErzbergerGroup and @pguruciaga at @embl! nature.com/articles/s41567-0…
Yu-Chiun Wang retweeted
Our paper is out in Nature Physics🎉 We uncovered how mouse epiblast cells acquire orientational order guided by tissue boundaries, combining 3D quantitative imaging with theory. A wonderful collaboration with @ErzbergerGroup and @pguruciaga at @embl! nature.com/articles/s41567-0…
Yu-Chiun Wang retweeted
👩🔬Read about the Mirai Alliance, a new program recently launched by the BDR Diversity WG to provide sustained support and mentorship for early-career women researchers at BDR in navigating their career and personal life transitions.
bdr.riken.jp/en/news/bdr-new…
#IDWGIS #WomenInSTEM
Yu-Chiun Wang retweeted
Press Release -- Why don't rapidly expanding head and torso tissues crash into each other in developing embryos? #science #biology #DevelopmentalBiology @BDR_RIKEN doi.org/10.1038/s41586-025-0… riken.jp/en/news_pubs/resear…
Yu-Chiun Wang retweeted
プレスリリース｜動物の形づくりに潜む力学的リスク
－ハエが進化させた、「組織同士の衝突」を防ぐ二つの仕組み－
doi: doi.org/10.1038/s41586-025-0…
詳細はこちらをご覧ください⬇️
riken.jp/press/2025/20250917…
#理研プレス
Yu-Chiun Wang retweeted
Ever wonder why tissues in developing embryos don't collide? #DevelopmentalBiology #Evolution #FlyEmbryos @BDR_RIKEN doi.org/10.1038/s41586-025-0… riken.jp/en/news_pubs/resear…
Yu-Chiun Wang retweeted
📣Wanna hear our story about the complex mechanical dynamics that cell populations undergo during the most important morphogenetic event? -Of course I am talking about gastrulation 🙂🤘. Join us this Wed at 10:00 CET, details -> @VGZT2020_21 @Prevedel_Lab
Yu-Chiun Wang retweeted
Latest from our lab!
We would like to express deepest gratitude to Dr. Niwa @TsukubaNiwaLab of the Univ. of Tsukuba and the co-authors.
We are pleased to present our latest paper, demonstrating that a gut hormone, CCHa1, responsive to a high-protein diet, regulates protein appetite. Disruptions in this system lead to excessive protein intake and its subsequent adverse effects.
nature.com/articles/s41467-0…
Yu-Chiun Wang retweeted
Excited to share our new preprint: "Epithelium Stratifies via Nucleation and Growth Induced by Foam-Geometric Instability". Led by Fukamachi (@Neginegi_sf), we combine 3D vertex modeling, imaging, and AFM to uncover epithelial layer formation mechanics.
biorxiv.org/cgi/content/shor…
Yu-Chiun Wang retweeted
Through live imaging enabled by new tools, Wuergezhen et al. visualises the hidden dynamics of the basement membrane (BM).
We show how BM turnover & expansion coordinate with cellular movements & divisions, highlighting their active & synergistic roles in skin morphogenesis.
Wuergezhen, @hirofujiwara et al. @BDR_RIKEN reveal basement membrane (BM) dynamics in hair follicle development. By developing mice expressing fluorescently tagged Col4a2, they show how BM turnover rates guide progenitor behavior and organ shape. hubs.la/Q02_6dXr0
Congrats. Super interesting discovery for the whole epithelium community!
We deeply appreciate @roadman2005 , @yuchiunwang, Fumio Motegi, and @Phogemon for their invaluable comments and support!
I hope folks @IISERPune and @richa_rikhy lab like where we are taking the story to on the foundation of the insightful and elegant discovery done there. Can’t wait to hear what feedback they have.
Life comes to a full circle. Grateful to be back at @IISERPune to present my work about yolk, part of which started during my PhD with @richa_rikhy.Thank you for hosting us! Hoping for many students to visit Japan and work at @BDR_RIKEN and with the amazing @yuchiunwang!
