Excellent work from the Igaki lab. Free ribosomal proteins that are not incorporated into ribosomes are degraded by the ubiquitin degradation system, preventing cellular stress from excess unused proteins.
jstage.jst.go.jp/article/csf…
We are pleased to announce our latest paper published in eLife. Here, we have visualized that confluent MDCK cells secrete PGE2 in a manner dependent on stoshastic calcium spikes. elifesciences.org/articles/8…
This year's Japan Prize will be awarded to Dr. Ron Evans, who is a mentor to Prof. Akira Kakizuka at Kyoto University and many other Japanese researchers in the field. Congratulations!
japanprize.jp/en/index.html
We report the visualization and quantification of PGE2 secreted by epithelial cells. A single calcium spike causes a cell to secrete 0.25 fmol PGE2, or 150 million PGE2, which activates PKA in 1000 neighboring cells. jstage.jst.go.jp/article/csf…
Michiyuki Matsuda retweeted
#OptoRevolution is off to an exciting start in Sanya, Hainan, with talks by Atsushi Miyawaki, @campbell_FPs, @jinzhanglab, and Michiyuki Matsuda covering new work in fluorescent proteins and biosensors.
Atsushi, I still have your freezer box!
Michiyuki Matsuda retweeted
二光子レーザーメンテナンスあれこれ。
出力高いレーザーをマウス用に配置したので、インキュベーター型が割を食ってしまうかもと思われた・・・が、!
脅威の回復っぷりにより、移動前の出力と変わらない(ちょっと上がったくらいの)状態に!!
#エンジニアさんが神がかり #ありがてえ #すげえ
Michiyuki Matsuda retweeted
蛍光生体イメージング室の二光子顕微鏡のレーザーは只今出力回復メンテナンス実施中です
作業は順調に進んでおります
利用再開は12/4を予定しております
今しばらくお時間下さいませ
#出力とっても回復してます #乞うご期待
Michiyuki Matsuda retweeted
ライトシート顕微鏡Webinarのお知らせ | 京都大学 大学院生命科学研究科 生命動態共用研究施設 lif.kyoto-u.ac.jp/dynamicliv…
もうすぐです。
Michiyuki Matsuda retweeted
ライトシート顕微鏡Webinarのお知らせ | 京都大学 大学院生命科学研究科 生命動態共用研究施設 lif.kyoto-u.ac.jp/dynamicliv…
業務連絡です。
ライトシート顕微鏡のWebinarを行います。我々の強みは【3種の機器比較】と【リモート】です。お待ちしてい居ります。
A mechanism to drive multivesicular bodies (MVBs) to exosome release has been reported by Mitsunori Fukuda's group. Good job!
jstage.jst.go.jp/article/csf…
Michiyuki Matsuda retweeted
Join us at the inaugural “Optorevolution: Exploring the Frontiers of Physiology with Light” conference!
It will be held in tropical Sanya, Hainan, China from November 18-22. Details and registration:
syiab.org.cn/OptoRevolution
Michiyuki Matsuda retweeted
ニコン次世代共焦点レーザー顕微鏡システムAX/AX R実機持ち込みデモ実施しました(2023/07/20) | 京都大学 大学院生命科学研究科 生命動態共用研究施設 lif.kyoto-u.ac.jp/dynamicliv…
こういうお手伝いも我々は行っております。デモは大人気でAM8からPM8までのスロットが埋まっていました。
doi.org/10.1247/csf.23028
Sakaue-Sawano and Miyawaki have published a paper describing a new cell cycle biosensor, Fucci5. In addition to the improved sensitivity, the new Fucci is free from the patents of fluorescent proteins, paving the way to the commercial use!
At last week's meeting of the Japanese Society for Cell Biology, the CSF Awards were presented to Dr. Ryosuke Nishimura and Dr. Satoru Takahash. Both received recommendations from over 20 council members. Congratulations!
jstage.jst.go.jp/article/csf…
jstage.jst.go.jp/article/csf…
Michiyuki Matsuda retweeted
All of the raw microscopy data from our publications (since 2013) are archived in SSBD:database / SSBD:repository. It's not only helpful for the research community, but also for ourselves. Thanks to @ssbd_en for all the support!
"Activity-dependent local protection and lateral inhibition control synaptic competition in developing ..." doi.org/10.1016/j.devcel.202… has been published on @Dev_Cell
Congrats! @TakeshiImaiLab -sensei!
SSBD:repository shares the original images of the paper doi.org/10.24631/ssbd.repos.…
Michiyuki Matsuda retweeted
Congratulations to Dr. Tobias Meyer – Newly Elected Member to the @americanacad ! Dr. Meyer's research focuses on understanding how mammalian cells integrate growth factor, cell-cell contact, and cell-matrix contact signals to control cell function. @tobiasmeyerlab
jstage.jst.go.jp/article/csf…
An excellent review paper on lipid modification of proteins from Mizushima Lab! I remember we fused CAAX box to a lot of proteins hoping to make them activated long time ago.
Michiyuki Matsuda retweeted
cGAMP非依存的に自然免疫分子STINGを活性化する化合物PAOを同定し、その作用機序を明らかにした。
J-STAGE Articles - A non-nucleotide agonist that binds covalently to cysteine residues of STING doi.org/10.1247/csf.22085
Michiyuki Matsuda retweeted
#JobAlert [Please RT🙏]
We are looking for a postdoc research fellow in studying collective cell dynamics at the Mechanobiology Institute, NUS🇸🇬. Don't hesitate to contact me if you have any questions. Looking forward to your application!
mbi.nus.edu.sg/jobs/seeking-…
Michiyuki Matsuda retweeted
#JobAlert [拡散希望🙏]
シンガポール国立大学メカノバイオロジー研究所の私たちのグループでは、細胞集団運動の研究に携わるポスドク研究員を募集しています。興味のある方はお気軽にお問い合わせください。是非応募をお待ちしております!
mbi.nus.edu.sg/jobs/seeking-…



















