Professor at Mayo Clinic
Joined October 2019
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Excited to share our article in @NatureComms describing a strategy to solve small #membraneprotein transporter structures using #cryoEM. We solved three structures of a 42 kDa efflux transporter from a single sample. Congratulations to the team and great collaboration w/@danengw
A fiducial-assisted strategy compatible with resolving small MFS transporter structures in multiple conformations using cryo-EM | Nat Commun
doi.org/10.1038/s41467-024-5…
This was an amazing effort by a talented group of people! Using #nmr and #mdsimulations we show how dynamics plays a key role in the mechanism of substrate recognition by the bacterial transporter EmrE.
@JianpingLi9, @calliesayshi and colleagues in @traasethlab reveal conformational dynamics underlie the drug recognition mechanism by the efflux transporter EmrE #nmr #membraneproteins
nature.com/articles/s41467-0…
Kudos to @JianpingLi9 for leading this effort to reveal the proton-coupling mechanism of the NorA transporter from S. aureus. It was a fun collaboration among Yan Li, Akiko Koide, Huihui Kuang, @TorresVJ_Lab, Shohei Koide, and @danengw.
#cryoem #transporters #mdsimulations
Proton-coupled transport mechanism of the efflux pump NorA | Nat Commun
doi.org/10.1038/s41467-024-4…
We used the FGF receptor kinase domain to understand how gatekeeper mutations lead to elevated activity. If you like experimental and computational biophysics, check it out. Thank you to the entire team for a fun collaboration. @BillyMarsiglia
pnas.org/doi/10.1073/pnas.22…
Also, thank you to @rachelbh24 for a nice and accessible write-up.
nyu.edu/about/news-publicati…
Nate Traaseth retweeted
The Marsiglia is officially open at UAB and looking to recruit a Research Technician with some experience in molecular biology, cell culture, or synthesis! If you’re interested, more information can be found at marsiglialab.com. Please retweet!
Nate Traaseth retweeted
I am thrilled to announce that I'll be starting my lab at NYU in the Department of Chemistry @nyuchemistry this fall as an assistant professor of chemical biology. Our lab will study protein self assembly mechanisms in the context of microbial adaptation.
as.nyu.edu/content/nyu-as/as…
Nate Traaseth retweeted
We updated our database of postdoc fellowships. There are many more than you may think (we list 349!), going beyond the well-known F awards from the NIH.
Download our public database here: research.jhu.edu/rdt/funding…
Nate Traaseth retweeted
In honor of his contributions to biophysics, Robert Tycko of @NIDDKgov and @NIH is being inducted to the National Academy of Sciences following his election in 2020. Watch the #NAS159 livestream: ow.ly/ulHh50IVLl3
Had a great time with @danengw and @DoctorDougB discussing our recent article on NorA — an efflux pump with importance in #MRSA. Thank you to Tori for inviting us!
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Really glad to see Lewis recognized for his accomplishments and contributions in biophysics and NMR spectroscopy.
In recognition of his contributions to NMR spectroscopy, Lewis E. Kay of @UoftB and @UofT is being inducted into the National Academy of Sciences. Watch the #NAS159 livestream: ow.ly/o3sI50IVO3A
Congratulations to Doug and all of our team who contributed to this recent work in @nchembio! A big thank you to everyone who made this story possible.
@danengw @TorresVJ_Lab @aroralabnyu @DavidBSauer @JianpingLi9 @xuhui_zheng
I’m excited to share that my PhD thesis work (helped along by many talented colleagues/collaborators) is now published! It’s a great read & reveals a new paradigm for combating antibiotic resistance
#antibioticresistance #effluxpumps #MRSA #therapeutics
nature.com/articles/s41589-0…
Thank you to @PenmatsaLab for writing an excellent summary of our work in @nchembio
Our latest news&views article summarising a wonderful story on NorA (an efflux pump) structure and its inhibition by a peptide derived from the CDR loop of a Fab by @traasethlab, @danengw and the KoideLab from @nyuniversity is out now @nchembio. @MBU_IISc
nature.com/articles/s41589-0…
Nate Traaseth retweeted
Congratulations to Professor Bonnie L Bassler of @Princeton for being recognized as a 2022 #Wolf Prize laureate in Chemistry.
Nate Traaseth retweeted
Ever wondered why a Na+ co-transporter bound with Na+ or substrate alone won’t flip to the other side, causing leakage?
Now a collaboration with the @Chris_mulligan lab has found an answer. The work was led by @DavidBSauer.
#CryoEM #membranetransport
biorxiv.org/content/10.1101/…
Ned's creativity inspired scientists beyond the field of DNA nanotechnology. He spoke his mind unfiltered and challenged powers that be. He was truly one of a kind and he will be missed.
We will miss Ned Seeman, founder of DNA Nanotechnology, who passed away at 75. as.nyu.edu/chemistry/news/fa…
Nate Traaseth retweeted
PhD positions are available in Magnetic Resonance #NMR #EPR (@c_e_avalos, @traasethlab, @ajerschow) @nyuchemistry to work on a wide range of projects. For more details on projects, facilities, and how to apply, see here: wp.nyu.edu/artsampscience-nm………. #Chemistry
Excited to share our recent work in @PNASNews. Congrats to @JianpingLi9 and @calliesayshi on their #NMR measurements to decipher key mechanistic insight on the transport mechanism of EmrE. Great job! pnas.org/content/118/41/e211…
We are hiring postdocs to work on efflux pumps involved in drug resistance and receptors involved in cell signaling. We use a range of biophysical tools including #NMR. Email me directly ([email protected]) if you are interested in our group. nyu.edu/fas/dept/chemistry/t…
Postdoctoral positions in the Nate Traaseth group @traasethlab at NYU in New York City, transporters involved in multidrug resistance in pathogenic organisms and receptors involved in human growth development, incl NMR wp.nyu.edu/traasethlab/ #NMRjobs #NMRchat #NMR #chemjobs
