Interested in personalized nutrition? Our new pub examining whether weight loss differs between genotype-concordant and genotype-discordant diets was published in @NatureComms and is featured as an Editors’ Highlight. A thread on findings below. Link: shorturl.at/JL238

This is preliminary data that needs to undergo peer review (presented as an abstract at ENDO) but incredibly relevant given AMA's new policy clarifying role of BMI as a measure in medicine. This data using DEXA suggests we are UNDERESTIMATING obesity, particularly among women and people who identify as Hispanic or Asian. Using standard obesity cutoffs for both BMI and total body fat, this study found DEXA rated 74% of participants as having obesity based on body fat compared with 36% based on BMI. Among the 64% of the study group who did not have obesity according to BMI, DEXA scans showed 53% of this subgroup did have obesity based on body fat percentages. Among those with a normal BMI, 43% had obesity according to DEXA. Further analysis showed that adding waist circumference to BMI to enlarge the diagnostic net for obesity, it cut the percentage of adults missed as having obesity by BMI alone nearly in half. Additional analyses showed that the rate of missed diagnoses of obesity by BMI was only most common among people of Hispanic or Asian ethnicity, with both groups showing a 49% rate of obesity by DEXA among those with normal-range BMIs. Link to article: medscape.com/viewarticle/993…