@tcpphami
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Postdoc @BiomedUCPH studying #Exercise #Muscle #Mitochondria
Joined January 2015
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The mighty mitochondria strike again!💪⚡️So excited to share our latest paper on exercise and mitochondrial adaptations. Endless gratitude to our fantastic collaborators and funders for their support!
In our latest study led by @tcppham, we found that the mitochondrial (mt) protein SLIRP is a PGC-1α target that regulates mt structure, respiration, and mt-mRNA in muscle. And exercise restored these functions, even with SLIRP disruption and low mt-mRNA! nature.com/articles/s41467-0…
Tang Cam Phung Pham retweeted
In this work, driven by amazing postdoc in our team @A_Irazoki, we found that adaptations to cancer in mice critically depend on housing temperature. biorxiv.org/content/10.1101/…
Tang Cam Phung Pham retweeted
Exciting news! My main paper for my PhD in the @ClemmensenC lab with @pranea is now published in @naturecomms! 🎉 It delves into how the body is naturally defended against excessive weight gain. A🧵👇#obesityresearch 1/11 nature.com/articles/s41467-0…
Tang Cam Phung Pham retweeted
2y research assistant position (master degree or equivalent) on international collaborative project with me and Christine Allen, Toronto, to test temperature-sensitive liposomes for muscle drug-targeting in mice🐀. Please help me spread the word 🙏 jobportal.ku.dk/videnskabeli…
Excited to share our latest work on the dynamic relationship between mitochondria and exercise! 🏋♀️ Dive into the details and share your thoughts in the thread below.🙏
Just submitted our manuscript🤞 We uncover the exercise-responsive mitochondrial-mRNA-stabilizing protein SLIRP, as a PGC-1α target that regulates mitochondrial structure, respiration, and mitochondrially-encoded-mRNA pools in skeletal muscle. Preprint: biorxiv.org/content/10.1101/…
Tang Cam Phung Pham retweeted
A fun little read about the discovery of GLUT4 more than 30 years ago 😃
@NatureRevEndo @UCPH_health
Journal club: Steffen H. Raun highlights two seminal papers from 1988 and 1989 that describe what is now known as glucose transporter 4 (£)
go.nature.com/3tOgBPq
Happy #FluorescenceFriday! @ed_battey working some Christmas magic on our mouse muscle samples. Stunning piece of art! 🎄🔬 #myotwitter
A new page in obesity research: Thrilled to share our latest publication uncovering a new regulator! Thank you to everyone who's been part of this journey.🙏 @NEXSKU @BiomedUCPH
In this study, driven by @tcppham🔥we integrated diet-induced obesity Drosophila and mouse models, metabolomics studies, and a multitude of metabolic screening approaches and identify TNIK as a conserved regulator of glucose and lipid metabolism in obesity science.org/doi/10.1126/scia…
Tang Cam Phung Pham retweeted
We are recruiting a PhD student to work with us within Molecular Lipid Metabolism. Deadline for applications August 10. Please share with relevant candidates: candidate.hr-manager.net/App…
Tang Cam Phung Pham retweeted
Online now! Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction dlvr.it/Sn6VKR
Tang Cam Phung Pham retweeted
I am perhaps a bit biased…🤷♀️ but this will be a fantastic opportunity to hear about a hot topic with very cool unpublished data🔥 Not to mention the great speakers @LisbethLVMoller and @Mona_ali1990 💪2 - 3pm EST Monday april 24th @MyogenesisGroup @BiomedUCPH @NEXSKU #myotwitter
Tang Cam Phung Pham retweeted
📣 There is still time to register! Don’t miss out on our exciting international PhD course titled “Skeletal Muscle Metabolism and Growth: Insights into Models and Mechanisms”. For more info and to register, click here: phdcourses.ku.dk/DetailKursu… @NEXSKU
Tang Cam Phung Pham retweeted
In press!
@DelfinisLuca in our lab found cancer causes weakness in quads + diaphragm BEFORE atrophy
BUT quads recover 'specific' force once atrophy occurs
Can we embrace muscle heterogeneity and the power of compensation in mice to guide new therapies?
insight.jci.org/articles/vie…
Tang Cam Phung Pham retweeted
Very excited to hear @SteffenRaun present some of our latest work on Rac1 and muscle exercise adaptation. Some of it unpublished so looking forward to hearing your thoughts. #muscle @BiomedUCPH @NEXSKU @UCPH_health @MYOTWlTTER
Tang Cam Phung Pham retweeted
Can we alter glucagon receptor signaling outcomes by changing it’s localization within the cell?
Yes, we can! Let me explain how (and why that matters). (1/7)
@RevathiSekar14 @kmotzler @helmholtz_diabc @HelmholtzMunich @Cell_Metabolism @CellPressNews
tinyurl.com/y5fbu2bc
Took some days to digest that my #phdlife came to an end. I'm overwhelmed with gratitude for my fantastic supervisors @lykkesylow and @proferikrichter, family, and all the wonderful people I met and work with during this journey. Thank you @MolecularUCPH @NEXSKU @BiomedUCPH
Tang Cam Phung Pham retweeted
Model matters 🐭
Fired up to share my first 1st-author publication in @FrontPhysiol !! We characterized ex vivo contractile properties in hindlimb muscles of common mouse strains. Both notable distinctions & tight similarities were observed #myotwitter
frontiersin.org/articles/10.…
Tang Cam Phung Pham retweeted
Replying to @tcppham
@tcppham and @A_Irazoki recently tested the reproducibility of the rotarod. We tested the same 14 mice 1 week apart. The correlation between the 1st and 2nd week was quite disappointing. Does anyone #myotwitter have similar experiences? Input/insights would be greatly appreciated
Tang Cam Phung Pham retweeted
Calling all mito-peeps! The MITOchat season is back. Please deposit your abstracts (with name and email!!) at
dropbox.com/request/r0gFes3P…
We look forward to chatting with you.
Tang Cam Phung Pham retweeted
Pre-print of our work in review on microtubule-based GLUT4 movement in insulin-resistant sk. muscle is out. @Jonas_Roland @kasparwp @MuscleBiology @SteffenRaun and more.
@UnreadPreps bot found it unreadable🤖Hope the reviewers can make sense of it😀!
biorxiv.org/content/10.1101/…