PhD molecular biologist with expertise in hematology @CincyChildrens. Outside of lab, I am a father, husband, sports coach, and scout leader. Views are my own.

Cincinnati, OH
Joined July 2008
🚨Apparently all NIH Study Sections have been suspended indefinitely. For those who don’t know, this means there won’t be any review of grants submitted to NIH Depending on how long this goes on for, this could lead to an interruption in billions in research funding.
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Dr. Emily Stepanchick from the Chlon lab (@tchlon) at @CincyChildrens led this study showing that DDX41 haploinsufficiency causes inefficient #hematopoiesis under stress ⚡ and cooperates with p53 mutations to cause hematologic malignancy. 👉 go.nature.com/3W7WR4C
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DDX41 mutations ⬇️⬇️ 🔹Germline pathogenic variants = relatively common (1/429) 🔹 Increased risk of MDS/AML 🔹Progression more common in somatic DDX41 variants 🔸Responsive to #venetoclax as previously published #leusm #leukemia #OncoAlert @BloodJournal doi.org/10.1182/blood.202302… – at Houston, TX
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The Vera & Joseph Dresner Foundation 2023 RFA for new research proposals in MDS for early career and established investigator awards is open. There's still time to submit a letter of intent for the 2023 cycle!
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The splicing workshop is back after the pandemic and returning to NYC! @IcahnMountSinai.
Excited to co-organize with ⁦@eirinipapapetr1⁩ the next Workshop on Splicing Factor Mutations and RNA biology in cancer here at Sinai. Registration is open (deadline April 3). Looking forward to seeing you in NYC. #RNAbiology #RNA #Splicing #Cancer
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The single most efficient investment in biomedical research would be to underwrite a non-profit competitor to Fisher and other laboratory service companies. Lab equipment should not come with a 1000% markup.
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Germline and Somatic Defects in DDX41 and its Impact on Myeloid Neoplasms | Happy to share this review co-authored with ⁦@tchlon⁩ | increasingly being recognized as most prevalent germline predisposition sx in myeloid malignancy with fav outcome! readcube.com/articles/10.100…
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Join the 8th international #BMF hybrid symposium organized by @aamdsif with expert specialists from all over a world. May 19-20, 2022. Register to participate for free: web.cvent.com/event/3cd53d06… The faculty includes:
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Parents have to choose their battles. 8 fights worth picking with your kids:
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Congrats to @dstarczynowski and @tchlon @ChildrensCBDI for publishing important #MDS #bonemarrow findings in @CellStemCell See the study: bit.ly/38wk7zx View the blog: scienceblog.cincinnatichildr…
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Regrettably, the @KeystoneSymp on Hematopoiesis (April 3-7, 2020) has been canceled due to the evolving circumstances involving the coronavirus. We apologize for the inconvenience to the speakers and attendees. More information to come from @KeystoneSymp: bit.ly/KShemato20
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There is only 1 week left to submit an abstract for the @KeystoneSymp April 3-7 2020 on the latest research in normal and malignant hematopoiesis. Check out the updated meeting info (bit.ly/KShemato20). #KShemato
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Miami Party! @rosslevinemd and @leonard_zon special act! The best party in town!! #ASH19
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There is only one week left to apply for @KeystoneSymp Hematopoiesis Meeting Scholarships (deadline Dec. 5): bit.ly/KSassistance. Not only are KS Scholarships prestigious, but they also provide invaluable networking and career-development opportunities.
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Get a job in TV they said... It'll be fun they said...
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