@RouxLab

A mix of physics and biology, from molecules to tissues

 Geneva, Switzerland
unige.ch/sciences/biochimie/labs/aurelien-roux/research/
Joined March 2014
  • Tweets2.3K
  • Following1K
  • Followers4.3K
185Media
This Children's Day, kids at Dolna-NCBS's on-campus childcare facility, enjoyed a magic show! For 25 years, Dolna has supported our researchers, empowering them to focus on their scientific careers with an assurance that their children are nearby in a safe & nurturing environment
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#NOTtheCover Unfortunately, we didn't make the cover @Nature. I still think our proposition deserves sharing. Enjoy the read: nature.com/articles/s41586-0…
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Now out in NSMB for those who missed our biorxiv back in 2023.. rdcu.be/dZSPQ
Harry Low’s Lab@thelowlab
27 Sep 2023
The missing piece in the bacterial #ESCRT-III story.. #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😎😵‍💫 Wonderful collaboration with @Colom_D @RouxLab… 1/2 biorxiv.org/content/10.1101/…
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Following the wave of scientific labs migrating to bluesky, we will soon close this account, please follow us on @rouxlab.bsky.social.
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It's great to see this now published @PhysRevE! doi.org/10.1103/PhysRevE.110… See below for a thread summarising the preprint - but of course you should read the paper for some solid mechanics...

Buckling by disordered growth

Buckling instabilities driven by tissue growth underpin key developmental events such as the folding of the brain. Tissue growth is disordered due to cell-to-cell variability, but the effects of this...

journals.aps.org
Pierre Haas@lepuslapis
11 Jul 2024
New #preprint: Buckling by disordered growth. A great #mechanics collaboration @mpi_pks @csbdresden with @RicardAlert, led by Rahul G. Ramachandran, available at arxiv.org/abs/2407.07540. @mpicbg
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Roux Lab retweeted
nature
@Nature
7 Nov 2024
How did the characteristic pattern of embryonic cell divisions during animal development evolve? nature.com/articles/d41586-0…

Clues to the origin of embryonic development in animals

Nature - Cell division analysed of a distant relative of animals.

nature.com
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Our latest #Ichthyosporean #EvoDevo story, led by M. Olivetta @ChandniBhickta @NChiaruttini & in co. with @burnsajohn is finally out @Nature . Link⏩: nature.com/articles/s41586-0… Preprint⏩: biorxiv.org/content/10.1101/… 1/5)
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Beautiful work! Congrats!
Steph Vassilopoulos@Biosdfp
4 Nov 2024
✨Cool to see our work with @WollertLab on the front page of @NatureSMB "Remodeling membranes into phagophore-like cups" rdcu.be/dY7e8
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🎉 We are excited to share that the Scienscope has received the Médaille de l’Innovation 2024 at the Dies academicus @unige_en! 💫 More info: ow.ly/S6VY50TYaXS #Innovation #scicomm #FacSciUNIGE #UNIGE
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Congratulations to both the Scienscope @sciences_UNIGE and the Poliscope from the Faculty of Social Sciences for this well-deserved award @unige_en which highlights their innovative contribution to the dialogue between science and society
Faculty of Science | UNIGE@sciences_UNIGE
1 Nov 2024
🎉 We are excited to share that the Scienscope has received the Médaille de l’Innovation 2024 at the Dies academicus @unige_en! 💫 More info: ow.ly/S6VY50TYaXS #Innovation #scicomm #FacSciUNIGE #UNIGE
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Roux Lab retweeted
EMBO@EMBO
1 Nov 2024
Welcome Nir Gov, Marko Kaksonen @marko_kaksonen, Snezhana Oliferenko @KingsCollegeLon, Benjamin Podbilewicz @Podbilewicz_lab, Dominique Bergmann, Susan Holmes, Tuuli Lappalainen @tuuliel, Mikhail Savitski @embl, Tanja Stadler @TanjaStadler_CH, Ariel Amir @Ariel_4321 #EMBOat60
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Leaving the '60 years of EMBO' meeting with a lot of new ideas and inspiration - and a walk through fields and forest. What a supportive science community - even ran into some colleagues from Geneva :) @UNIGEnews
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🔬✨ New insights into tissue regeneration! Our study uncovers a novel mechanochemical mechanism in Hydra, revealing how mechanical forces and Wnt signaling work together to create intricate tissue patterns. #Cnidarians #Hydra #Biology #Regeneration biorxiv.org/content/10.1101/…

Mechanochemical Patterning Localizes the Organizer of a Luminal Epithelium

The spontaneous emergence of tissue patterns is often attributed to biochemical reaction-diffusion systems. In Hydra tissue regeneration, the formation of a Wnt signaling center serves as a well-kn...

biorxiv.org
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Roux Lab retweeted
FEBS@FEBSnews
31 Oct 2024
Congratulations to Omaya Dudin of the University of Geneva, Switzerland on being awarded a FEBS Excellence Award, which provides €100,000 in research funding @dudin_o @Ch_Bioch_UNIGE, @UNIGEnews #FEBSExcellenceAwards febs.org/news/febs-excellenc…
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Quite humble to be joining the @FEBSnews community, & certain this support will help us explore the #Evolutionary #Cell Biology of #multicellular #development at the root of #animals using our fav #Ichthyosporea Kudos to all lab members & collaborators who made this possible🙏🙏
FEBS@FEBSnews
31 Oct 2024
Congratulations to Omaya Dudin of the University of Geneva, Switzerland on being awarded a FEBS Excellence Award, which provides €100,000 in research funding @dudin_o @Ch_Bioch_UNIGE, @UNIGEnews #FEBSExcellenceAwards febs.org/news/febs-excellenc…
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Great story from @AnaisBailles on the role of #mechanics in initiating the remarkable #Hydra reformation from #singlecells to functional #animal. Supported by @GiuliaSerafin12 HCR, @carldmodes & @zechnerlab modeling & Heino Andreas Hydra husbandry @mpicbg @csbdresden @PoLDresden – at Kelsterbach, Deutschland
Anaïs Bailles@AnaisBailles
30 Oct 2024
Very happy to share the first article from my postdoc work in the Tomancak lab! biorxiv.org/content/10.1101/…. We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
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🚨New preprint alert🚨Interested to know how clathrin-independent endocytosis and retrograde transport in cancer cells tune their ability to stimulate CD8 T cell activation? This story is for you #cell #biology #immunology. Congrats to the first author @ShiqiangXu 🙌🏻
bioRxiv Cell Biology@biorxiv_cellbio
30 Oct 2024
Clathrin-independent endocytosis and retrograde transport in cancer cells promote cytotoxic CD8 T cell activation biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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Very happy to share the first article from my postdoc work in the Tomancak lab! biorxiv.org/content/10.1101/…. We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
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Excited to share our latest work on an image analysis paradigm that combines cell state and morphology analyses of patient biopsies at single cell resolution to uncover clinically relevant head-and-neck #cancer phenotypes! @CellCellPress cell.com/cell/fulltext/S0092… tweetorial👇
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Excited and humbled to share some big news: I am starting a new chapter as an Assistant Professor @uniofwarwick working in the new Cellular Interfaces Program by @jitumayor_lab @Warwick_CMCB @warwickmed Lab doors open in March 2025. Stay tuned for info, updates and positions.
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