Neuroscience stuff | Postdoc @Stanford_PMHW | https://xitter.cf/t.co/xjh6fV4j58 |
Joined September 2018
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pines retweeted
How does executive function develop during adolescence—and when is it most closely linked to mental health? See our @NatureMentalHealth paper：Developmental Benchmarks of Executive Function Reveal Sensitive Periods for Adolescent Mental Health.
nature.com/articles/s44220-0…
pines retweeted
1/6 🍄 What happens in the brain under psilocybin?
I’m excited to share our new preprint:
“Brain-wide reconfiguration of burst firing by psilocybin reveals 5-HT2A-dependent circuit dynamics.”
biorxiv.org/content/10.64898…
#Psilocybin #Psychedelics #Neuroscience #OpenScience
pines retweeted
PNAS
Traveling-wave transcranial alternating current stimulation (twtACS) causally links neural timing to cognitive function
This study developed a new brain stimulation method called traveling-wave transcranial alternating current stimulation (twtACS). Unlike conventional brain stimulation, twtACS creates electrical waves that move across the brain in a specific direction, similar to natural neural traveling waves.
The researchers showed that these artificial traveling waves could:
Change the timing of neural activity in the brain
Control how signals propagate across brain regions
Improve cognitive performance in humans depending on the direction of the wave
They confirmed these effects using:
Human intracranial recordings
Monkey neural recordings
Human behavioral experiments
The study suggests that traveling waves are not just correlated with cognition but may causally influence cognitive function. This introduces a new way to noninvasively manipulate brain communication and potentially treat neurological disorders.
pnas.org/doi/full/10.1073/pn…
pines retweeted
How does TMS — a treatment for depression — reshape dysfunctional brain circuits?
In our new Cell paper, we identify a cell type-specific prefrontal mechanism linking accelerated iTBS to antidepressant-like behavioral effects and circuit plasticity.
cell.com/cell/fulltext/S0092…
pines retweeted
What are the neural correlates of human behavior?
Much research has approached versions of this question between individuals but not within individuals. Are results from these 2 approaches similar? No!
In over 4000 individuals, the neural correlates of cognitive control diverged between vs. within individuals -- a case of non-ergodicity and Simpson’s paradox.
We think that non-ergodicity may be an important principle in human neuroscience. [1/12]
pines retweeted
Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development.
🔗 bit.ly/3QMLG0K
pines retweeted
Our first work from my PhD period: biorxiv.org/content/10.64898…
In this study, we propose a computational model and theoretical framework for neural dynamics. This is only a starting point, but it also reflects our broader academic ambition.
pines retweeted
We think of white matter as highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My PhD paper, “Two Axes of White Matter Development”, is now out in @NatureComms!🧠
🔗bit.ly/wm2axes
pines retweeted
My second first author paper of graduate school - Sex differences in response to violence: role of salience network expansion and connectivity on depression - is now published in Translational Psychiatry! rdcu.be/eLYg6
pines retweeted
Emotions are core to the human experience 😆😮🙂😊☹️😠😳😑. But how do they arise? Our brain-wide ⚡recordings in humans and mice reveal some answers @ScienceMagazine. A big team effort and debut paper from @Stanford's new Human Neural Circuitry program. bit.ly/4dEyX7Z
pines retweeted
Breathing isn’t just for life—it’s a brain pacemaker!
This excellent review reveals how each breath sends sensory waves that globally synchronize neural networks - with implications for "functional connectivity". Congrats to the authors!
👉 doi.org/10.1038/s41583-025-0…
pines retweeted
‼️PhD Position now available in my lab‼️
Do you like:
* Neurodegenerative disease?
* Neuroimaging and/or multi-omics?
* AI and data-driven life science?
Want to work with @RikOssenkoppele Alexandra Young and Laura Wisse?
Apply here: lu.varbi.com/what:job/jobID:…
Please rt/share 🙏
pines retweeted
Thrilled to announce our study, “Connectional Axis of Individual Functional Variability: Patterns, Structural Correlates, and Relevance for Development and Cognition,” now published in @PNASNews pnas.org/doi/abs/10.1073/pna…
Excited to share our work “Connectional axis of individual functional variability: Patterns, structural correlates, and relevance for development and cognition,” now out at @PNASNews pnas.org/doi/10.1073/pnas.24….
pines retweeted
Our preprint detailing our novel approach to identifying personalized neuromodulation targets to treat severe, refractory OCD using brain mapping is now out on MedRxiv. Here, we describe our first SEEG-guided DBS case for OCD at UCSF: medrxiv.org/cgi/content/shor…
pines retweeted
(1/17) Now out on bioRxiv‼️Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025.02.24.6…
Funded by @NIMHgov
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health biorxiv.org/content/10.1101/… #biorxiv_neursci
pines retweeted
Our work linking GWAS and pharmacological treatments in psychiatric disorders is now in JAMA Psychiatry jamanetwork.com/journals/jam…
🧬💊🎯
Big thanks to @bendfulcher @AFornito @BellgroveMark
🧵👇
pines retweeted
Now out in @NatMentHealth 🥳🥳🥳 this is the 2nd study of my dissertation with Carrie Bearden, co-led with @dehughes14 💫💫nature.com/articles/s44220-0…
Check out @Sarah_Chang_ 's and my latest preprint: medrxiv.org/content/10.1101/…. We investigate the effects of attention and probe the developmental specificity of polygenic signal on psychotic-like experiences in adolescents using ABCD.
pines retweeted
Topography of putative bidirectional interaction between hippocampal sharp wave ripples and neocortical slow oscillations biorxiv.org/cgi/content/shor… #biorxiv_neursci
pines retweeted
✨New Preprint!✨ Sex differences in psychiatric disorders often show up in adolescence as disparities in prevalence, symptoms, and treatment outcomes. We aimed to better understand sex diffs in brain organization that might lead to these disparities!
t.ly/x6oxC
🧵⬇️
pines retweeted
Building predictive models of mental health has been challenging. Our latest article demonstrates that neuroimaging features are a small yet important part of the equation, especially among adolescents with subclinical symptoms: doi.org/10.1038/s41380-024-0…
