@papers_bar

Popular research papers https://xitter.cf/t.co/oYO7p6A5uq https://xitter.cf/t.co/H0iO5rcfdp https://xitter.cf/t.co/jo9PHiu6SQ https://xitter.cf/t.co/oMf3AGVvtJ

papers.bar
Joined June 2021
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labml.ai@labmlai21 Jun 2023
🥳 Our "Annotated Research Paper Implementations" Github repo reached 25,000 stars! github.com/labmlai/annotated… It has over 50 paper implementations. Thank you everyone for the support!
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Long-term duration of protection of ancestral-strain monovalent vaccines and effectiveness of the bivalent BA.1 boosters against COVID-19 hospitalisation during a period of BA.5, BQ.1, CH.1.1. and XBB.1.5 circulation in England med.papers.bar/paper/85c4324… ... 🧵 👇
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Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements bio.papers.bar/paper/551e021… CRISPR-based gene activation is a promising therapeutic approach for gene therapy. Here, we describe an... 🧵 👇
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(2/3) .. experimental framework that combines highly multiplexed perturbations with single-cell RNA sequencing to identify cell-type-specific, CRISPRa-responsive cis-regulatory elements.
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Flo Chardon@FloChardon29 Mar 2023
Absolutely thrilled to share mine and @TroyMcDiarmid’s work describing the development of a multiplexed, scalable CRISPRa cell type-specific screening framework that is able to identify…(1/n) biorxiv.org/content/10.1101/…

Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements

CRISPR-based gene activation (CRISPRa) is a promising therapeutic approach for gene therapy, upregulating gene expression by targeting promoters or enhancers in a tissue/cell-type specific manner....

biorxiv.org
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A stability theorem for bigraded persistence barcodes math.papers.bar/paper/28d432… We define the bigraded persistent homology modules of a finite pseudo-metric space X using the Vietoris-Rips filtration of X. We prove... 🧵 👇
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(2/2) .. the stability theorem for the big raded persistent double homology modules and barcodes.
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The Subspace Flatness Conjecture and Faster Integer Programming math.papers.bar/paper/97425d… In a seminal paper, Kannan and Lov\'asz ( 1988) considered a quantity which denotes the best volume-based lower bound on the... 🧵 👇
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(2/3) .. covering radius of a convex body. We settle this conjecture up to a constant in the exponent by proving that $O(\log n)$..
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Victor Reis@vetohaze28 Mar 2023
Replying to @vetohaze
According to the exponential time hypothesis, we don't expect integer programming to be solvable in time faster than 2^O(n). We still don't know whether a 2^O(n) time algorithm exists! [4/4] Link to the paper: arxiv.org/abs/2303.14605

The Subspace Flatness Conjecture and Faster Integer Programming

In a seminal paper, Kannan and Lovász (1988) considered a quantity $μ_{KL}(Λ,K)$ which denotes the best volume-based lower bound on the covering radius $μ(Λ,K)$ of a convex body...

arxiv.org
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Invariant preservation in machine learned PDE solvers via error correction physics.papers.bar/paper/db6… Machine learned partial differential equation (PDE) solvers trade reliability of standard numerical methods for... 🧵 👇
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(2/3) .. potential gains in accuracy and/or speed. In this paper, we design more reliable machine learned PDE solvers by preserving discrete analogues of the continuous invariants of the underlying PDE.
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Nick McGreivy
@NMcGreivy29 Mar 2023
There has been a lot of interest in using ML to solve PDEs. While ML solvers can be fast, they are not very reliable. In this paper, I show how to design invariant-preserving ML solvers that, like standard solvers, guarantee stability & conservation laws. arxiv.org/abs/2303.16110

Invariant preservation in machine learned PDE solvers via error correction

Machine learned partial differential equation (PDE) solvers trade the reliability of standard numerical methods for potential gains in accuracy and/or speed. The only way for a solver to guarantee...

arxiv.org
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An uncountable number of proofs of Pythagoras Theorem math.papers.bar/paper/7dd458… We give an infinite number of proofs of Pythagoras theorem. Some can be classified as 'fractal proofs'... 🧵 👇
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Francis Villatoro@emulenews31 Mar 2023
#arXiv An uncountable number of proofs of Pythagoras Theorem arxiv.org/abs/2301.06812 "An infinite number of proofs of Pythagoras theorem classified as `fractal proofs'."
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Covid-19 and post-acute sick leave: a hybrid register and questionnaire study in the adult Danish population med.papers.bar/paper/85c4324… Long covid follows 10-20% of first-time SARS-CoV-2 infections. Being female, and... 🧵 👇
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(2/3) .. having certain pre-existing conditions such as fibromyalgia increased risks for taking substantial sick leave. Further research exploring this heterogeneity is urgently needed.
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(3/3) Here is a popular Tweet about the paper👇
Emmanuel@ejustin461 Apr 2023
DENMARK. SOCIETAL BURDEN of LONG COVID and risk factors Covid-19 and post-acute sick leave: a hybrid register and questionnaire study in the adult Danish population medrxiv.org/content/10.1101/…
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CryoET shows cofilactin filaments inside the microtubule lumen bio.papers.bar/paper/ab61730… Cryogenic electron tomography of Drosophila S2 cell protrusions found filaments inside the microtubule lumen. frequency of these... 🧵 👇
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(2/3) .. filaments increased upon inhibition of the sarco/endoplasmic reticulum Ca2+ ATPase. Subtomogram averaging showed..
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Carter Lab@Carter_Lab1 Apr 2023
Happy to share our new preprint: We imaged protrusions of Drosophila cells with cryoET and found filaments in the microtubule lumen. Subtomo-avg and RNAi suggest these are cofilin-bound actin (cofilactin). By @CamillaVenturaS in collab with Stephen Rogers. biorxiv.org/content/10.1101/…
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