Neuroscientist at @HHMIJanelia, https://xitter.cf/t.co/dmKkVR210v…
Virginia, USA
Joined April 2011
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Nelson Spruston retweeted
🖥️A new method developed by @AlexHillsley @janfunkey & collaborators counts the individual molecules contained in a single spot of light detected by a fluorescence microscope-a quantity important for understanding the underlying biology of a living system
janelia.org/news/new-method-…
Nelson Spruston retweeted
🧪Researchers, led by @T___Kawashima @zq_wei & @MishaAhrens, are decoding how neurons carry out computations carefully calibrated to an animal’s movement & environment to precisely regulate the release of neuromodulators.
janelia.org/news/new-researc…
Nelson Spruston retweeted
🚶Aimlessly wandering around a city or exploring the new mall may seem unproductive, but new research led by @Lin_Zhong_ion @marius10p & @computingnature suggests it could play an important role in how our brains learn. 🧠
🔗janelia.org/news/zoning-out-…
Nelson Spruston retweeted
💻 A new class of simplified ‘minimodels’ developed by @Du_Fengtong @NunezKant @marius10p @computingnature can predict the visual responses of individual neurons in the primary visual cortex, helping shed light on how we see. 👀
➡️ janelia.org/news/new-computa…
Nelson Spruston retweeted
A new tissue expansion method developed by the Wang (@mengwang939) & Tillberg (@TillbergPaul) labs & the @LingjunLi2 lab @UWMadison enables scientists to use mass spec imaging to simultaneously detect 100s of molecules in single cells in intact tissues➡️ janelia.org/news/new-techniq…
I love this new technique developed my colleague James Liu and his lab at Janelia.
🧬A new imaging technique developed by the Liu Lab uses a novel DNA barcode system to track hundreds of RNA & protein molecules in single cells within thick biological samples, providing a full picture of how these structures are organized inside tissues. janelia.org/news/new-method-…
I’m excited about this highly collaborative project by @sunw37, @JohanWinn, and many other talented contributors. Read more about how our @HHMIJanelia team imaged thousands of neurons in mouse hippocampus as mice learned cognitive tasks over several days:
janelia.org/news/mapmaking-i…
1/12 How do animals build an internal map of the world? In our new paper, we tracked thousands of neurons in mouse CA1 over days/weeks as they learned a VR navigation task. @nspruston @HHMIJanelia, w/ co-1st author @JohanWinn
Video summary: youtube.com/watch?v=yw_4uVur…
Paper: nature.com/articles/s41586-0…
1/11 How are cognitive maps formed during learning?
Very excited to share new work by outstanding co-first authors @sunw37 and @JohanWinn and other wonderful collaborators @HHMIJanelia biorxiv.org/content/10.1101/…
10/11 We hope this work provides useful data for gaining insight into the formation of cognitive maps and inspires novel AI learning algorithms, for example, in unsupervised learning and model-based RL. #NeuroAI
11/11 In addition to the co-first authors @sunw37 and @JohanWinn, many others made critical contributions. Big thanks to co-authors Maanasa, @Chongxi_lai, Koichiro, Michalis, Rachel, and James, as well as many others recognized in the Acknowledgments!
(1/10) I’m pleased to share our new paper by two talented postdocs: Xinyu Zhao & Ching-Lung Hsu @hiallen72
Read on if you’re interested in how hippocampus helps animals perform memory-guided behavior through both fast & slow learning.
cell.com/neuron/fulltext/S08…
(9/10) Implication: How does the hippocampus infer separate latent states, i.e. contexts? @honisanders @gershbrain Either by massive sensory changes signaling a different environment or subtle changes but with a strong behavioral contingency.
Related... nature.com/articles/s41593-0…
(10/10) Huge thanks again to Xinyu and Ching-Lung @hiallen72 for this beautiful work.
cell.com/neuron/fulltext/S08…
Also, congrats to Ching-Lung for starting his new lab at Academia Sinica! @SinicaFans @IbmsSinica