@nirfriedman
 Israel
Joined June 2008
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  • Following205
  • Followers357
3Media
Newest preprint from our lab. We show that we can detect abnormal expression in hepatocytes from blood samples. #cfChIPseq #liquidbiopsy #cfDNA
medRxiv@medrxivpreprint5 Jun 2023
Identification of hepatocyte immune response in Autoimmune Hepatitis from human plasma cfChIP-seq medrxiv.org/cgi/content/shor… #medRxiv
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אחד העצורים במחאה נגד המהפכה המשפטית בירושלים הוא פרופ' עמית דניאלי, חבר סגל באוניברסיטה העברית ופרופ' למדעי המחשב. במשטרה טוענים שנעצר על תקיפת שוטרים. זה התיעוד: לקול קריאות "איפה הייתם בחווארה?" שוטרי יס"מ מתנפלים על פרופ' דניאלי ומכניסים אותו לניידת תוך שניות בודדות מ"התקיפה" – at Israel
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What’s happening in Israel? Please read and share this thread that I wrote to help clarify the dramatic (and complicated) events that threaten to turn Israel into a dictatorship in a matter of weeks 👇
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cfChIP-seq now added to the list of methods for #LiquidBiopsy #CancerScreening.
James Hadfield@coregenomics6 Jul 2022
Subtyping of Small Cell Lung Cancer using plasma cell-free ChIP-Seq offers a new option for liquid biopsy detection of cancer subtype - potential for Dx, MRD, etc. biorxiv.org/content/10.1101/… @sbarnettARK
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New pre-print. Wonderful collaboration with Anish Thomas and his group at the NCI. We show that liquid biopsy can identify small-cell lung cancer (SCLC). Moreover, we can identify its sub-type which today requires solid biopsy. biorxiv.org/content/10.1101/…

Subtyping of Small Cell Lung Cancer using plasma cell-free nucleosomes

Small cell lung cancer (SCLC) is an aggressive malignancy with exceptionally poor prognosis and limited therapeutic advances in the past few decades. Although SCLCs are treated as a single disease...

biorxiv.org
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Proud to see this paper appear online. Massive effort by Alon Chappleboim and Daphna Joseph-Strauss and beautiful story that opens up some intriguing hypotheses. Transcription feedback dynamics in the wake of cytoplasmic mRNA degradation shutdown academic.oup.com/nar/advance…

Transcription feedback dynamics in the wake of cytoplasmic mRNA degradation shutdown

Abstract. In the last decade, multiple studies demonstrated that cells maintain a balance of mRNA production and degradation, but the mechanisms by which c

academic.oup.com
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What an honor! @haitham_amal and I received the Krill award from the #wolf foundation 💪🙏🍾
AFHU
@AmFriendsHU6 Apr 2022
.@HebrewU Researchers Awarded 2022 Krill Prize for Excellence in Scientific Research buff.ly/3jiBTvn #science
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HUMAN GENOME! IT COMPLETE AGAIN AGAIN! science.org/doi/10.1126/scie…

The complete sequence of a human genome

Since its initial release in 2000, the human reference genome has covered only the euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. Addressing the remaining...

science.org
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Nir Friedman retweeted
JOAN BRUGGE@BruggeMe12 Aug 2021
Congratulations to Yaara Oren, an exceptional postdoctoral fellow, for orchestrating this study on mechanisms underlying cycling cancer therapy persisters in @Nature Great collaboration between the Regev and Brugge labs. #avivregev #cancertherapy nature.com/articles/s41586-0…
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Nir Friedman retweeted
HUJI CSE@CseHuji12 Aug 2021
With great sorrow, we sadly announce the death of our friend and colleague Prof. Naftali Tishby from the School of Computer Science and Engineering and extend our condolences to the family.
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דיון וועדת המומחים של משרד הבריאות היום נראה כמו משחק מכור. שמעתי את נחמן אש אתמול בגל"צ, וכל חבר/ת וועדה ששמע אותו הבין/ה בדיוק מה ההחלטה שהוא רוצה - לחסן. שלישי. עכשיו. לפני אישור ה-FDA. לפני שיש מסד נתונים מספק. אני לא מומחה רפואי. אבל כמי שלקח חלק בהרבה מאוד תהליכי קבלת
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Nir Friedman retweeted
Andy Slavitt
@ASlavitt28 Jul 2021
As of this week, the dam is beginning to break publicly so I will comment. Google just announced a vaccination requirement, the VA has, CA has, NY has and others are on the path. Including Biden publicly commenting that this is being considered 4 all federal ees & contractors.2/
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A great opportunity for postdoctoral fellows (And I am happy to sponsor suitable applicants) azrielifoundation.org/the-az…
Nir Friedman retweeted
Barkai Lab@BarkaiLab9 Jul 2021
Our new paper, led by Gilad Yaakov and @FJonas15 just came out! @NatureBiotech ⏱We used molecular timers to measure histone exchange genome-wide. 1/5 nature.com/articles/s41587-0…
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We made the cover! nature.com/articles/s41587-0… Design: my talented daughter's illustration
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And some shameless parental promotion reofillust.com/

Reo F. Illustration and graphic design

Reo F. Illustration features illustrations, graphic design and more by artist Reo F.

reofillust.com
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Yay!
European Research Council (ERC)
@ERC_Research22 Apr 2021
Replying to @ERC_Research
🎉Congratulations to the 209 new ERC Advanced Grant #ERCAdG recipients 🏅! Full list👉bit.ly/AdGWinners
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“Parallel genetics of regulatory sequences using scalable genome editing in vivo” with @borauyar @AltunaAkalin @N_Rajewsky @BIMSB_MDC @MDC_Berlin cell.com/cell-reports/fullte… here is the story: 👇👇👇 1/13
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Exciting collaboration with @LinialMichal and Nir Kalisman labs and many others @BrielleEsther! We use targeted in situ cross-linking mass spectrometry (CLMS) and integrative modeling for three #SARS-CoV-2 proteins: Nsp1, Nsp2 and nucleocapsid (N) 1/ biorxiv.org/content/10.1101/…

Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures...

Atomic structures of several proteins from the coronavirus family are still partial or unavailable. A possible reason for this gap is the instability of these proteins outside of the cellular...

biorxiv.org
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Nir Friedman retweeted
bioRxiv@biorxivpreprint18 Feb 2021
A comprehensive fitness landscape model reveals the evolutionary history and future evolvability of eukaryotic cis-regulatory DNA sequences biorxiv.org/cgi/content/shor… #bioRxiv
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