Postdoc @UWMadison. Gene regulation, NGS data analysis, RNA biology, computational biology, computer science. He/Him/His. Views my own.
Madison, WI
Joined February 2019
- Tweets19
- Following98
- Followers50
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Mike Wolfe @[email protected] retweeted
Ecstatic to share that I will be defending my Ph.D. in Biochemistry on June 4th at 1:30 CT. Please let me know if you would like to join the seminar virtually and I will send a streaming link via DM. Excited to share my post-Ph.D. plans soon!
Mike Wolfe @[email protected] retweeted
We are hiring postdoc researchers for my lab at UT Southwestern Medical Center @UTSW. Join us to study transcription and regulation in pathogenic bacteria using multidisciplinary approaches. Please RT. Thank you! #newPI
Mike Wolfe @[email protected] retweeted
“One of the most common ways we communicate scientific findings [left-hand panels] can lead people to drastically overestimate the size and importance of those findings… thankfully there's a simple solution”: add individual data points [right-hand panels] pnas.org/doi/10.1073/pnas.23…
Excited to announce a new paper in PNAS today!
An illusion of predictability in scientific results: Even experts confuse inferential uncertainty and outcome variability
pnas.org/doi/10.1073/pnas.23…
Joint w/ great coauthors @_szhang, @P_Heck, @MichelleNMeyer, @cfchabris & @dggoldst
Mike Wolfe @[email protected] retweeted
What an amazing Gordon Research Conference on Mechanisms of Microbial Transcription @MoMT2023 Thanks you to all the organizers @wig_r . Come and join us for the 2025 Gordon Research Seminar # Microbial Transcription. Nick @npokorzynski and Daniel @DPlazaSaez will make it great!
🚨 Thrilled to announce that @npokorzynski (@YaleMed) and I (@CamBiochem) will be Chair and Vice Chair for the 2025 Gordon Research Seminar on Mechanisms of #Microbial Transcription!🦠
@GordonConf
Thanks @CaoXinyun and @wig_r for the amazing #MoMT2023 😊
#ASMicrobe #microbio24
Mike Wolfe @[email protected] retweeted
Genetic context OUTSIDE of the promoter region can have a strong impact on gene expression in E.coli. Pleased to share my work in @FreddolinoLab and with Chase Lindeboom.
Even strong promoters can be silenced depending on genetic context in E. coli. Our new article @NAR_Open doi.org/10.1093/nar/gkac787 authors @ScottAScholz , Chase Lindeboom. Thanks for reviewer feedback leading to key additions!
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Congrats! @GirlsWhoCodeUM
Our preprint describing our curriculum to teach Python for data science in our #GirlsWhoCode club is now on bioRxiv! 💻🐍📊
biorxiv.org/content/10.1101/…
🧵 Check out the thread below for a summary:
Mike Wolfe @[email protected] retweeted
“Other countries have social safety nets. The U.S. has women...Women do all of the unpaid service for the institutions in their lives, and then they go home and do even more.” annehelen.substack.com/p/oth…
Happy to share some of my graduate work exploring how context impacts the control of mRNA stability by the human PUM proteins. A great collab between the Freddolino, Goldstrohm, Campbell, and Ljungman labs @Campbell_RNALab @umichrna : rnajournal.cshlp.org/content…
Mike Wolfe @[email protected] retweeted
Excited to share a preprint with some of my thesis work done in the @LandickLab! We used cool techniques to unravel connections between H-NS filament structure and DNA sequence. Thanks to my co-authors for making this project fun! @cmhustmyer @mikebwolfe @JessenErik
Hybrid analysis reveals how DNA sequence governs genomic location and DNA contacts of bacterial chromatin H-NS filaments biorxiv.org/cgi/content/shor… #bioRxiv
Honored to be a part of a great paper!
Excited to share @biochemBeth's latest pre-print exploring the role of DNA sequence in dictating H-NS filament structure. We use new methods to probe H-NS both within an individual filament and genome wide and present an updated model! Happy to contribute with @mikebwolfe.
Mike Wolfe @[email protected] retweeted
Bayesian Data Analysis, by Andrew Gelman, John Carlin, Hal Stern, David Dunson, Aki Vehtari, and Donald Rubin is now available as a free PDF: stat.columbia.edu/~gelman/bo…
Dynamic landscape of protein occupancy across the Escherichia coli chromosome disq.us/t/3lq3vnw
Mike Wolfe @[email protected] retweeted
SO! Finally! Here we have it: For those who need it, who want it, who have asked for it or who could just use it occasionally — dark mode is now available on the desktop app as well as mobile, for everyone. Read more: slackhq.com/dark-mode-for-sl…
ALT An image with a picture of Dark Mode with a picture of the dark UI of the slack app, as well as the words "Dark Mode, we have it. Thank you for your patience. We hope you like it." And this is true. Thank you for waiting while we strive to make accessibility core to every part of our product. We know it's taken a long time. We're sorry. We're working hard to make things better. Thank you for sticking with us. xxx
Mike Wolfe @[email protected] retweeted
Looking forward to hosting Zak Campbell on Monday! 4pm in BSRB @UT_Dallas @Campbell_LabUTD
Proud of our recent work coming out in @CellSystemsCP!
Does genomic position matter for gene expression in bacteria? Yes! I'm pleased to share our work in @CellSystemsCP on mapping transcriptional propensity in E. coli at a high resolution cell.com/cell-systems/fullte…
Our review article covering HT-sequencing methods to determine RNA decay is out! Use this link for open access until April 11: authors.elsevier.com/c/1YbkV…