@massspecpro

Helping you stay on top of the mass spec landscape with news, articles, events, patents and more. Run by @mikegoodwin.

massspecpro.com
Joined September 2010
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We are sad to share news of Jean Futrell's passing. He was a GIANT of mass spec and a MIGHTY advocate & supporter of @asmsnews. Our thoughts are with Jean's family, friends, and colleagues. Learn more about Jean: asms.org/publications/journa… asms.org/about/history/oral-… #TeamMassSpec
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Devin Schweppe@dschweppe115 Oct 2024
Comet's open-source search engine has been a boon for our proteomics methods developments (like real-time search). Over the last two-years we became curious whether Comet's search speeds could be improved to keep pace with modern instruments and large sample cohorts.
bioRxiv Bioinfo@biorxiv_bioinfo15 Oct 2024
Comet fragment-ion indexing for enhanced peptide sequencing biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
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Devin Schweppe@dschweppe127 Sep 2024
Our lab is looking for a postdoc @uwgenome/@UW/@UWISCRM! We tackle a wide range of biological Qs from cell-specific responses to perturbation to molecular consequences of aging. We also work hard on new #TeamMassSpec methods to scale the # of proteomics samples we can analyze.
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Theoretical Assessment of Indistinguishable Peptides in Mass Spectrometry-Based Proteomics #AC pubs.acs.org/doi/10.1021/acs…

Theoretical Assessment of Indistinguishable Peptides in Mass Spectrometry-Based Proteomics

Abstract. Mass-spectrometry-based proteomics has advanced with the integration of experimental and predicted spectral libraries, which have significantly i

pubs.acs.org
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Multi-pass, single-molecule nanopore reading of long protein strands nature.com/articles/s41586-0… --- #proteomics #prot-paper
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The #OrbiTOF is published in IJMS. Very satisfying to finally shine light on this decade-long project and unique technology. Could easily have been the next big thing in mass analysis, had the Astral analyzer not proved so promising.
Mass Spec Pro@massspecpro11 Aug 2024
The OrbiTOF Mass Analyzer: Time-of-Flight Analysis via an Orbitrap Quadro-Logarithmic Field with Periodic Drift Focusing. - ScienceDirect sciencedirect.com/science/ar…
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Check out our work on optimized ion detection, now published in JASMS. Here, we have multiple technologies, including 10 kV post-acceleration, electrostatic tilt correction, and a novel ion detector combined into a single assembly. #OrbitrapAstral pubs.acs.org/doi/10.1021/jas…

A High Dynamic Range Ion Detector for Multireflection Time-of-Flight Analyzers

Abstract. Reflectron-based time-of-flight analyzers rely on subnanosecond detector time response to achieve acceptable resolving power for low–mid-mass, mu

pubs.acs.org
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Danielle Swaney@dlswaney31 Jul 2024
This @mjmaccoss preprint about QC is too real. Like when your turbo pump explodes and sends shrapnel into every crevice of your mass spec causing problems for half a year. This QC platform help you know when your instrument is actually all clean again :) biorxiv.org/content/10.1101/…

A framework for quality control in quantitative proteomics

A thorough evaluation of the quality, reproducibility, and variability of bottom-up proteomics data is necessary at every stage of a workflow from planning to analysis. We share real-world case...

biorxiv.org
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Is there any online tool where one can look up the m/z of N15 labelled version of a list of peptides quickly?? Thanks very much.. #TeamMassSpec
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🚨🚨Calling All Mass Spec Artists!!🚨🚨 🎨🎨 Ru a hot, young, talented Art-eest with a burning🔥passion 4 mass spec? JASMS needs u🫡!! Your talents could serve as the default cover for the journal Details at the link below! (Pic unrelated) asms.org/publications/journa…
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The ionization method and source interface have a huge impact on ion internal energy and fragmentation. Check out the pre-print of our new review article. Don't hesitate to send feedback and suggestions while this article is under peer review. doi.org/10.26434/chemrxiv-20…

THERMOMETER IONS, INTERNAL ENERGIES, AND IN-SOURCE FRAGMENTATION IN AMBIENT IONIZATION | ChemRxiv

Ionization and fragmentation are at the core of mass spectrometry. But they are not necessarily separated in space, as in-source fragmentation can also occur. Here we survey the literature published...

chemrxiv.org
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Top-down proteomics nature.com/articles/s43586-0… --- #proteomics #prot-paper
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(JASMS) [ASAP] Ion Mobility Separations Using Cocentric Architecture dlvr.it/T87QZK (RSS) #MassSpecRSS #JASMS
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Vadim Demichev
@DemichevLab9 Jun 2024
Excited to announce DIA-NN version 1.9, our software suite for proteomics data processing! A range of cool new features and general performance improvements. We consider it the most significant update in the history of DIA-NN. github.com/vdemichev/DiaNN/r…
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Let's get those #ASMS2024 reprints sent out! From the app/planner, select "More" then "My Reprint Requests". That will bring up a list of everyone who asked for your poster. Email the list to yourself and send your poster out. I want that reprint!
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Lingjun Li@LingjunLi26 Jun 2024
Fun gathering with an amazing group of women mass spectrometrists at #ASMS2024 last night. Thanks @LabLaskin for organizing! Everyone had a great time. @FemalesInMS @asmsnews @J_ASMS #TeamMassSpec
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Eberlin Lab@EberlinLab17 May 2024
This is how we roll! 🛼🚨 In our new paper, we placed our Orbitraps on wheels and moved them through hospital hallways and elevators while acquiring data! We also demonstrate MasSpec Pen analysis in the OR on battery power🔋@BCM_Surgery @BCMFromtheLabs pubs.acs.org/doi/10.1021/acs…

Data Acquisition and Intraoperative Tissue Analysis on a Mobile, Battery-Operated, Orbitrap Mass...

Abstract. Mass spectrometry has been increasingly explored in intraoperative studies as a potential technology to help guide surgical decision making. Yet,

pubs.acs.org
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My team (Astral) is expanding and looking for new talent. We're hunting software, instrumentation and application experts. Have a look! jobs.thermofisher.com 230864BR Senior Software Scientist 230865BR and 230863BR Senior Scientist 230862BR Staff Scientist

Careers at Thermo Fisher Scientific | Thermo Fisher Scientific jobs

home

jobs.thermofisher.com
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Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in timsTOF #NatCommun nature.com/articles/s41467-0…

Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in...

Nature Communications - Immunopeptidomics is crucial for the discovery of potential immunotherapy and vaccine candidates. Here, the authors generate a ground truth timsTOF dataset to fine-tune the...

nature.com
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Adding Color to Mass Spectra of Biopolymers: Charge Determination Analysis (CHARDA) Assigns Charge State to Every Ion Peak #JASMS pubs.acs.org/doi/10.1021/jas…

Adding Color to Mass Spectra of Biopolymers: Charge Determination Analysis (CHARDA) Assigns Charge...

Abstract. Traditionally, mass spectrometry (MS) output is the ion abundance plotted versus the ionic mass-to-charge ratio m/z. While employing only commerc

pubs.acs.org
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