@massspecpro

Helping you stay on top of the mass spec landscape with news, articles, events, patents and more. Run by @mikegoodwin.

massspecpro.com
Joined September 2010
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While I have enjoyed Twitter for many years, I think I'm going to give BlueSky a try. Just can't get behind Elon's recent activities.
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We are sad to share news of Jean Futrell's passing. He was a GIANT of mass spec and a MIGHTY advocate & supporter of @asmsnews. Our thoughts are with Jean's family, friends, and colleagues. Learn more about Jean: asms.org/publications/journa… asms.org/about/history/oral-… #TeamMassSpec
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[ASAP] Simulation of Space Charge Effects in Fourier Transform Quadrupole Ion Traps (FT-QITs) dx.doi.org/10.1021/jasms.4c0…

Simulation of Space Charge Effects in Fourier Transform Quadrupole Ion Traps (FT-QITs)

Abstract. We present ion dynamics simulations regarding the effect of space charge on the performance of Fourier transform quadrupole ion traps (FT-QITs) w

pubs.acs.org
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[ASAP] Hybrid Quadrupole Mass Filter–Radial Ejection Linear Ion Trap and Intelligent Data Acquisition Enable Highly Multiplex Targeted Proteomics dx.doi.org/10.1021/acs.jprot…
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Is Native Mass Spectrometry in Ammonium Acetate Really Native? Protein Stability Differences in...

Abstract. Ammonium acetate is widely used in native mass spectrometry to provide adequate ionic strength without adducting to protein ions, but different i

pubs.acs.org
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#TeamMassSpec is pretty spicy on here the last few days.
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Mass Spec Pro retweeted
Devin Schweppe@dschweppe115 Oct 2024
Comet's open-source search engine has been a boon for our proteomics methods developments (like real-time search). Over the last two-years we became curious whether Comet's search speeds could be improved to keep pace with modern instruments and large sample cohorts.
bioRxiv Bioinfo@biorxiv_bioinfo15 Oct 2024
Comet fragment-ion indexing for enhanced peptide sequencing biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
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A Novel Accurate Peak Extraction Algorithm of Mass Spectrometry Based on Iterative Adaptive Curve...

Abstract. In the analysis of mass spectrometry, the peak identification from the overlapped region is necessary yet difficult. Although various methods hav

pubs.acs.org
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Mass Spec Pro retweeted
Devin Schweppe@dschweppe127 Sep 2024
Our lab is looking for a postdoc @uwgenome/@UW/@UWISCRM! We tackle a wide range of biological Qs from cell-specific responses to perturbation to molecular consequences of aging. We also work hard on new #TeamMassSpec methods to scale the # of proteomics samples we can analyze.
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Theoretical Assessment of Indistinguishable Peptides in Mass Spectrometry-Based Proteomics #AC pubs.acs.org/doi/10.1021/acs…

Theoretical Assessment of Indistinguishable Peptides in Mass Spectrometry-Based Proteomics

Abstract. Mass-spectrometry-based proteomics has advanced with the integration of experimental and predicted spectral libraries, which have significantly i

pubs.acs.org
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This is a cool talk about ion traps from my colleague Philip Remes
Mass Spec Pro@massspecpro21 Sep 2024
youtu.be/gcVr4DCmYvw
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Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

The exploration of protein structure and function stands at the forefront of life science and represents an ever-expanding focus in the development of proteomics. As mass spectrometry (MS) offers...

analyticalsciencejournals.onlinelibrary.wiley.com
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Calculating and Reporting Coefficients of Variation for DIA-based Proteomics | bioRxiv biorxiv.org/content/10.1101/…

Calculating and Reporting Coefficients of Variation for DIA-based Proteomics

The Coefficient of Variation (CV) is a measure that is frequently used to assess data dispersion for mass spectrometry-based proteomics. In the current era of burgeoning technical developments, there...

biorxiv.org
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Multi-pass, single-molecule nanopore reading of long protein strands nature.com/articles/s41586-0… --- #proteomics #prot-paper
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I have seen the slides, and they look quite good.
Brian Searle@briansearle12 Sep 2024
This should be an exciting, educational lecture on ion traps! I am really looking forward to moderating audience questions for Philip during his talk tomorrow. Come join us!
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Achieving Electron Capture Dissociation in the Radio Frequency Linear Ion Trap without the Assistance of a Magnetic Field─A Simulation Study pubs.acs.org/doi/10.1021/jas…

Achieving Electron Capture Dissociation in the Radio Frequency Linear Ion Trap without the Assist...

Abstract. It is extremely difficult to inject a low-energy electron beam into a conventional radiofrequency (RF) linear ion trap for electron capture disso

pubs.acs.org
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Writing with Mass-Selected Ions Using a Dynamic Field Wien Filter pubs.acs.org/doi/10.1021/jas…

Writing with Mass-Selected Ions Using a Dynamic Field Wien Filter

Abstract. We have designed and constructed a low-cost Wien filter based on strong permanent magnets and integrated it into an ion soft-landing instrument t

pubs.acs.org
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Advancing the Prediction of MS/MS Spectra Using Machine Learning pubs.acs.org/doi/10.1021/jas…

Advancing the Prediction of MS/MS Spectra Using Machine Learning

Abstract. Tandem mass spectrometry (MS/MS) is an important tool for the identification of small molecules and metabolites where resultant spectra are most

pubs.acs.org
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