Jose L. Avalos retweeted
Proud to share a preprint describing the optoPlateReader (oPR), a device for optogenetics, spectroscopy, and feedback control in *each well* of a 96-well plate. Tremendous effort by our ugrad @iGEM team. Led by Saachi Datta and team mentor @WillBenman. 👇
biorxiv.org/content/10.1101/…
Jose L. Avalos retweeted
#PrincetonU researcher José Avalos has been awarded funding from the Dept. of Energy (@DOEscience) for chemical and biofuel research. The award builds on preliminary data from research funded by Princeton Engineering’s (@eprinceton) Project-X.
Jose L. Avalos retweeted

Reuters@Reuters29 Apr 2021
🇺🇸!
United StatesConnected via WebLocation may be affected by a proxy or VPN.Account-level information, not a live location or per-post device.
EU calls for rethink of GMO rules for gene-edited crops reut.rs/32XDrDd
Jose L. Avalos retweeted
Today we mourn the loss of Professor Angelika Amon. She was a remarkable person, an incredible and creative scientist, a lively and spirited colleague, and devoted mentor. Her impact and legacy live on, and will be perpetuated through everyone she touched.
Jose L. Avalos retweeted
Researchers at @UW have designed inhibitors that block the interaction between #SARSCoV2 and human cell receptor ACE2, paving the way for therapeutics that could be delivered more easily than antibodies. fcld.ly/rp1ll80
Jose L. Avalos retweeted
Molecular tools that can switch on and off with light. @javalosLAB @toettch and team have developed a class of light-switchable "OptoBinders" to control cellular processes. One potential application includes improved production of biofuels.
acee.princeton.edu/acee-news…
Jose L. Avalos retweeted
Replying to @javalosLAB
@javalosLAB and @toettch present a pair of papers demonstrating optical control of monobody and nanobody activity, respectively.
go.nature.com/2E2c0iA
go.nature.com/2Ye75SF
Jose L. Avalos retweeted
Genetically engineered yeast makes medicinal plant products. @JoseMontLo and @javalosLAB outline the potential of this exciting breakthrough in our N&V
go.nature.com/2YX58KM
Jose L. Avalos retweeted
The end of IPTG for protein expression? I always thought: damn, this IPTG shit is expensive!
Our OptoLAC paper is out with many additions to the BioRxiv. These circuits can replace IPTG with light as the inducing agent for chemical and protein production in E.coli (and probably other PTG-inducible functions). Congrats Makoto!! rdcu.be/b6SNW
Jose L. Avalos retweeted
A new paper from @javalosLAB engineered the classical lac operon into a blue light-regulated transcriptional system for metabolic engineering and protein production. Readable link at rdcu.be/b6Tqs. nature.com/articles/s41589-0…
Jose L. Avalos retweeted
The argument is simple: use recovery investment "not to restore the old world but to help create the new one." Will coronavirus halt or accelerate the transition to a clean energy economy? nyti.ms/2WeSq9a
Jose L. Avalos retweeted
Our ventilator team is spooling up and wants to build up our software side! More updates soon!
Calling all GUI wizards and Raspberry Pi gurus! Volunteer to write code that SAVES LIVES by joining @DJCohenEtAl @Princeton MAE team building critical care ventilator for COVID-19 patients. Please spread the word! cc @covidbrains 1/
Jose L. Avalos retweeted
Dear America,
Please remember that in these, the darkest of times, you turned to the arts for comfort, and to the sciences for hope.
Perhaps, when this is all over, you’ll consider giving these endeavors your more full-throated support.
Yours most sincerely,
A scientist
Jose L. Avalos retweeted
Incredible ingenuity
Brazilian creative solution to prevent virus transmission in a world suffering from shortage of PPEs #COVID19
Jose L. Avalos retweeted
Friends, I learned last night over Zoom drinks that ya'll're baking so much that there's a shortage of yeast?! I, your local frumpy yeast geneticist have come here to tell you this: THERE IS NEVER A SHORTAGE OF YEAST. Here's where I'm a viking. Instructions below.
Jose L. Avalos retweeted
I wasn't sure how evil private equity might be. But this might be the most evil thing I've seen yet propublica.org/article/coron…
Jose L. Avalos retweeted
Excited to share this paper!
How to train your protein to bind based on light condition with up to 150 fold changes in Kd. Hint: give it a lot of LOV :).
biorxiv.org/content/10.1101/…
Jose L. Avalos retweeted
Replying to @ShorterLabGroup @javalosLAB
whoa, that went live fast! this was a fun one - finally getting to the kinds of affinity changes that would make for a really awesome light-switchable binder to a more diverse set of protein partners :D
Jose L. Avalos retweeted
"Here [the authors] present a light-controlled monobody that works in vitro and in vivo, whose affinity for its target exhibits a 300-fold shift in binding affinity upon illumination." an exciting new tool from the labs of @javalosLAB and @toettch! biorxiv.org/content/10.1101/…
Jose L. Avalos retweeted
Shocker: Climate deniers are dead wrong. Despite what they constantly argue, it turns out that climate models are fairly good. And yeah, we are in trouble. #notahoax #ClimateChangeIsReal agupubs.onlinelibrary.wiley.…































