Scientist at Princeton interested in life sciences applied to human health, energy, and the environment

Princeton, NJ
Joined March 2018
Jose L. Avalos retweeted
Proud to share a preprint describing the optoPlateReader (oPR), a device for optogenetics, spectroscopy, and feedback control in *each well* of a 96-well plate. Tremendous effort by our ugrad @iGEM team. Led by Saachi Datta and team mentor @WillBenman. 👇 biorxiv.org/content/10.1101/…
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#PrincetonU researcher José Avalos has been awarded funding from the Dept. of Energy (@DOEscience) for chemical and biofuel research. The award builds on preliminary data from research funded by Princeton Engineering’s (@eprinceton) Project-X.
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Jose L. Avalos retweeted
Reuters
@Reuters29 Apr 2021
EU calls for rethink of GMO rules for gene-edited crops reut.rs/32XDrDd
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Jose L. Avalos retweeted
Today we mourn the loss of Professor Angelika Amon. She was a remarkable person, an incredible and creative scientist, a lively and spirited colleague, and devoted mentor. Her impact and legacy live on, and will be perpetuated through everyone she touched.
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Researchers at @UW have designed inhibitors that block the interaction between #SARSCoV2 and human cell receptor ACE2, paving the way for therapeutics that could be delivered more easily than antibodies. fcld.ly/rp1ll80
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Molecular tools that can switch on and off with light. @javalosLAB @toettch and team have developed a class of light-switchable "OptoBinders" to control cellular processes. One potential application includes improved production of biofuels. acee.princeton.edu/acee-news…
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Replying to @javalosLAB
@javalosLAB and @toettch present a pair of papers demonstrating optical control of monobody and nanobody activity, respectively. go.nature.com/2E2c0iA go.nature.com/2Ye75SF
Genetically engineered yeast makes medicinal plant products. @JoseMontLo and @javalosLAB outline the potential of this exciting breakthrough in our N&V go.nature.com/2YX58KM
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The end of IPTG for protein expression? I always thought: damn, this IPTG shit is expensive!
Our OptoLAC paper is out with many additions to the BioRxiv. These circuits can replace IPTG with light as the inducing agent for chemical and protein production in E.coli (and probably other PTG-inducible functions). Congrats Makoto!! rdcu.be/b6SNW
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The argument is simple: use recovery investment "not to restore the old world but to help create the new one." Will coronavirus halt or accelerate the transition to a clean energy economy? nyti.ms/2WeSq9a
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Our ventilator team is spooling up and wants to build up our software side! More updates soon!
Calling all GUI wizards and Raspberry Pi gurus! Volunteer to write code that SAVES LIVES by joining @DJCohenEtAl @Princeton MAE team building critical care ventilator for COVID-19 patients. Please spread the word! cc @covidbrains 1/
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Jose L. Avalos retweeted
Dear America, Please remember that in these, the darkest of times, you turned to the arts for comfort, and to the sciences for hope. Perhaps, when this is all over, you’ll consider giving these endeavors your more full-throated support. Yours most sincerely, A scientist
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Jose L. Avalos retweeted
Incredible ingenuity
Brazilian creative solution to prevent virus transmission in a world suffering from shortage of PPEs #COVID19
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Jose L. Avalos retweeted
Friends, I learned last night over Zoom drinks that ya'll're baking so much that there's a shortage of yeast?! I, your local frumpy yeast geneticist have come here to tell you this: THERE IS NEVER A SHORTAGE OF YEAST. Here's where I'm a viking. Instructions below.
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Jose L. Avalos retweeted
whoa, that went live fast! this was a fun one - finally getting to the kinds of affinity changes that would make for a really awesome light-switchable binder to a more diverse set of protein partners :D
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"Here [the authors] present a light-controlled monobody that works in vitro and in vivo, whose affinity for its target exhibits a 300-fold shift in binding affinity upon illumination." an exciting new tool from the labs of @javalosLAB and @toettch! biorxiv.org/content/10.1101/…
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Shocker: Climate deniers are dead wrong. Despite what they constantly argue, it turns out that climate models are fairly good. And yeah, we are in trouble. #notahoax #ClimateChangeIsReal agupubs.onlinelibrary.wiley.…
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