Drosophila neurobiology, bioinformatics, gene function and regulation, developmental biology

Washington, DC
Joined April 2015
Scientists and friends mourn the passing of Ben-Zion "Benny" Shilo, who died on April 14, 2025, at age 73. The Weizmann Institute of Science geneticist and developmental biologist leaves an indelible legacy through his groundbreaking research on cellular communication mechanisms and his transformative educational initiatives, notably the landmark developmental biology courses at NCBS-TIFR, Bangalore.
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Our latest out today @Nature! We revisit a century-old theory and show that metabolic gradients work hand-in-hand with genetic&signalling instructions to shape the embryo. Glucose isn't just an energy source, it acts as a major conductor of the body plan🍬 nature.com/articles/s41586-0…
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Our latest preprint. @L_Lampe, @clarenewell24 and colleagues figured out how metamorphosing #Drosophila avoid drying out. The larva makes a lipid barrier of hyper-long hydrocarbons (>C27 and longer) and stores it in the fat body until needed by the pupa. tinyurl.com/3keukxsz
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Gene discovered that rejuvenates mouse brain cells in *old* mice but not *young* ones ⚡️
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Online Now: The structural landscape of Microprocessor-mediated processing of pri-let-7 miRNAs dlvr.it/TF8hKM
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Large-scale map of RNA-binding protein interactomes across the mRNA life cycle dlvr.it/TF0sx2
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BREAKING: Kamala Harris’ campaign just released their first ad taking on JD Vance’s inability to say Donald Trump lost the 2020 election. Retweet to make sure every American sees this ad.
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BREAKING: In a stunning response, swing voters are saying it was JD Vance’s refusal to admit Donald Trump lost in 2020 that made them swing to Kamala Harris and Tim Walz’ side. Retweet so all Americans see this and know Walz won the debate.
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Congratulations! Our Japanese colleagues kept #Drosophila in total darkness for over decades and these flies are apparently fine with their eyes and behavior! This is consistent with your beautiful work. But debaters always ask, how about spontaneous mini synaptic potentials? – at Missouri, USA
This past weekend, @GregorFPS and I were award @MCB_Harvard's Meselson Prize for "Most Beautiful Experiment" This was for showing that brain activity is not necessary for neural maturation: nature.com/articles/s41467-0… For more info, see: mcb.harvard.edu/department/n…
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We are thrilled to share that @eLife has now published our "reviewed preprint" on how signaling from the gut to glia connects intestinal inflammation to sleep in #Drosophila! elifesciences.org/reviewed-p… @HalbergLab @Colombani_lab @lundbeckfonden @novonordiskfond @Carlsbergfondet
We are excited to share our recent work on gut-to-glia communication linking intestinal inflammation with sleep in #Drosophila! Many thanks to @HalbergLab and Andersen and @Colombani_lab! @lundbeckfonden @novonordiskfond @Carlsbergfondet @UCPH_Research biorxiv.org/content/10.1101/…
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Connectomes, connectomes, connectomes: @MertErginkaya and I wrote a @CurrentBiology dispatch about the FANC fly VNC connectome papers from the @casa_tuthill and @darbly labs in @Nature, and discuss how connectomes change the way we analyze circuits for behavior. Link below ⬇️
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BREAKING: In a shocking leak, Donald Trump just told the leaders of Project 2025 that his most exciting work with them lies ahead. Donald Trump is openly admitting he will implement Project 2025. Retweet so all Americans see this.
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Happy to share my editorial in Disease Models and Mechanisms @DMM_Journal on the power of Drosophila in modeling human disease mechanisms. journals.biologists.com/dmm/…
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Let's try this again - look's like twitter can't handle the video 😂. Really excited to share the lab's first Drosophila paper and it's a big one. Check out our preprint shorturl.at/gqrvO where we present the complete neural connectome of an animal circadian clock
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BREAKING: Morning Joe just SLAMMED Trump for blaming Democrats for their “rhetoric.” They rolled the tape on inflammatory remarks made by Donald Trump over the years. Retweet to make sure MAGA can’t rewrite history.
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BREAKING: In a stunning leak, Donald Trump gave the keynote address at the Heritage Foundation where he announced the work the foundation did (Project 2025) would be crucial to his policy goals. Retweet so all Americans know Trump will enact Project 2025.
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This is really beautiful work by @lydiaborjon in @Hoosierflyman 's lab. If you were at the last @CSHL Neurobiology of Drosophila meeting and attended Lydia's wonderful talk, you know what I mean. Also, Lydia is in the job market - and any department would be lucky to have her.
Preprint just dropped!🎙️We discover molecular mechanisms of the excruciatingly painful sting of the Scarlet Velvet Ant (Dasymutilla occidentalis). Title: "Multiple mechanisms of action of an extremely painful venom." 🧵 1/N biorxiv.org/content/10.1101/…
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