Assistant Professor @UAMShealth Department of Neuroscience Astrocytes, microglia, metabolism, and multiple sclerosis. https://xitter.cf/t.co/PyK35Cv0nM
Little Rock, AR
Joined April 2017
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- Following244
- Followers214
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Cory Willis retweeted
How tissue dissociation impacts scRNA-seq: Standard protocols can lose reactive astrocytes & key pathological signatures! 🧠
Check out our new paper in Molecular Neurobiology on optimized workflows: link.springer.com/article/10…
#SingleCell #Neuroscience #Astrocytes
Cory Willis retweeted
Interferon-responsive microglia are increasingly recognized to impact brain health in development, aging, and neurodegenerative conditions. To determine regulators of type I IFN-responsive microglia, we performed the first genome-wide CRISPRi screen in iPSC-derived microglia.
Cory Willis retweeted
Developmentally programmed p21+ senescent cells have a lifelong role in the integrity of the blood-brain & blood-CSF barriers
📹 L. Ashley Watson, Zoe Adelsheim & Mackenzie J. Carter et al Meharena lab @UCSanDiego in @CellCellPress
➡️ bpod.org.uk/archive/2026/6/2…
Cory Willis retweeted
Astrocytes viewed through the lens of their proteomes and subproteomes — a Review by Vanessa H. Casha, Ling Wu, James A. Wohlschlegel & Baljit S. Khakh
nature.com/articles/s41583-0…
Cory Willis retweeted
Bad experiences with supervisors are common among early-career researchers and one of the leading reasons they leave academia
go.nature.com/4vmygrr
Cory Willis retweeted
it was always dumb to talk about killing so called zombie cells in the context of healthy aging
#Senolytic therapies may carry previously underappreciated neurological risks.
@uconnhealth researchers found #dasatinib + #quercetin combination unexpectedly induces white matter damage in the central nervous system of healthy mice, confirmed both in vivo and in vitro.
Cory Willis retweeted
Our study is out in @ScienceMagazine! It shows that CAR-expressing astrocytes (CAR-A) can recognize and clear amyloid aggregates, reducing pathology and restoring microglial homeostasis in AD models.
Led by Yun Chen, Alex Liu and @khainotkaiorky!
doi.org/10.1126/science.ads3…
Cory Willis retweeted
Check out our new Center for Integrative Connectomics website!
@neuralmapping & his team investigate why specific brain cell types are vulnerable to neurodegenerative disease. This work aims to identify therapeutic targets & improve patient outcomes 🧠
👉 cic.ini.usc.edu
Cory Willis retweeted
The CA1 has more than 'superficial' and 'deep' cell type layers! 🐭🧠🧬
Check out the thread from my PhD student and first-author @mc_pachicano describing the results in our new paper published today in @NatureComms!
@KECKSchool_USC @USCLONI @USC_ZilkhaNeuro
🎉 Super excited to share our new paper in Nature Communications — my first first-author publication!
We reveal a hidden laminar architecture within the hippocampal CA1 that spans the entire dorsal—ventral axis.
🧠✨
👇
📄nature.com/articles/s41467-0…
Cory Willis retweeted
Just out! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41586-0…. New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8
Cory Willis retweeted
Proud to see our work out in @NeuroCellPress !
cell.com/neuron/fulltext/S08…
With Bongsoo Park, Dimitris Tsitsipatis @DanielZucha @LukasValihrach @irina_mohorianu @Pluchinolab @BeermanHSCaging !
Cory Willis retweeted
Equilibrative nucleoside transporter 2 modulates inosine catabolism to influence astrocyte metabolism and reactivity dlvr.it/TNZTNv
Cory Willis retweeted
Meet our Reproduction, Development and Lifelong Health Theme Leads. New Lead Sumru shares her hopes for the Theme. Learn more on our website: bio.cam.ac.uk/ #BiologicalSciences
ALT Teal graphic with white Reproduction, Development and Lifelong Health logo (three people behind health cross). Headshots of Theme Leads Sumru Bayin, Alex Cagan, Amanda Sferruzzi-Perri, Mekayla Storer. Quote from Dr Sumru Bayin says: 'As Theme Leads, we look forward to enabling new connections that inspire transformative interdisciplinary research. Building on my experience with the Complex Tissue Regeneration Grand Challenge, I aim to uncover new synergies and unlock new opportunities across the School of Biological Sciences.'
It was a pleasure to have written this N&V with @Pluchinolab for @NatMetabolism!
Delighted to have written together with @exosomeguy this N&V for @NatMetabolism
Cholesterol fuels microglia in chronic stroke
nature.com/articles/s42255-0…
Cory Willis retweeted
Science Without Anguish Series 3 in out:
Don’t believe everything you think!
What happens when we confuse our mental shortcuts with reality? Why we excuse ourselves but blame others. And why we don’t realise we’re making life harder for ourselves.
sciencewithoutanguish.com/bl…
Cory Willis retweeted
Neurons and astrocytes have distinct organelle signatures and responses to stress dlvr.it/TN7bvJ
Cory Willis retweeted
New @NatureGenet review from our NIH SenNet @sennetresearch OMICS WG co-led by @shenglilab
We share practical considerations for identifying, characterizing & spatially mapping #CellularSenescence, plus computational #multiomics insights!! nature.com/articles/s41588-0…
Cory Willis retweeted
Protocol to isolate oligodendrocytes, microglia, endothelial cells, astrocytes, and neurons from a single mouse brain using magnetic-activated cell sorting🤗
biorxiv.org/content/10.1101/…
Cory Willis retweeted
Online now: G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation dlvr.it/TM6YVm
Cory Willis retweeted
Embracing the Modern Biochemistry of Brain Metabolism - Bolaños - Journal of Neurochemistry onlinelibrary.wiley.com/doi/…
