Our group studies the molecular and systems biology of blood cell development. We focus on T cells and the way they split from other developmental alternatives.
@Caltech
Joined April 2020
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How horribly true! And it's still a rejection when "this has already been shown" is talking about your own paper that you somehow published by that time...
2021 rejection: “it will never work”
2022 rejection: “it will never work”
2023 rejection: “it will never work”
2024 rejection: “this has already been shown”
😂 nature.com/articles/d41586-0…
Very pleased to see this! Then there really can be true naive T cells in adult people. Then also humans and mice are not so extremely different either. Thanks, @Joshilabyale and @SamuelBHume !
Very interesting study. Fits with previous work from @DonnaFarber3 on thymic T cell output continuing much later in life than we initially thought. The connection to cancer is very interesting.
And it was transformative to work with @Kueh_Lab when he was in our lab and also the @ElowitzLab. Looking at familiar immune cell types in different ways thru systems biology revealed many deep new insights. Would love to recruit new fellows to follow in @Kueh_Lab 's footsteps!
Thank you Katie! It was an amazing experience to work with @ElowitzLab and also with @evrlab, who opened my eyes to the immune cells and the fate decisions that they make.
Dear @peiwei_chen , I am ecstatic for you! Congratulations! What a joy it has been to work with you on teaching about stem cells and the immune system, and learning about your own highly creative work with @AlexeiAravin. Cheers, many, many congratulations, and all good luck!!
elated and humbled to get the @WeintraubAward 😊
thanks to my super supportive advisor @AlexeiAravin my committee @Pselaphinae @BronnerMarianne @Angela_Stathop @evrlab and sooooo many other people who have helped me along the way!
Harald was incredibly important for our field. He had a huge impact and died too young. It is marvelous that they have dedicated the 2024 Midwinter Conference in Immunology to him. He was not my mentor but a huge inspiration.
(Had to sneak out of "retirement" for this RT)
Although not part of the conference, it is always touching to see that it is dedicated to a giant in the immunology field and my PhD (and PostDoc) mentor. We all have missed Harald's brilliance...#Immunology
mwc2024.org/index.php
Hi all. Thank you so much for all we've learned from your wonderful posts in the past few years, the joy of sharing our work with you, & your kind words. But I am heartsick about what's happened to this platform lately and think I need to take a break from it. Please be well!
The Division of Biology and Biological Engineering (BBE) at @Caltech is searching for tenure-track Faculty candidates studying fundamental processes in Developmental & Organismal Biology! Assistant Professor candidates preferred; Sept 30 deadline. See : applications.caltech.edu/job…
Thrilling science and wonderful human connections. Congratulations to Alejandro and Britta and to all the participants!
We're thrilled that our new paper about the intricate ways that Runx factors work to start the T-cell developmental program is out in NI. This is a huge credit to @Boyoungshin who drove the project from start to finish in every way. Please don't miss the supplement-so much there!
Exciting new manuscript from @evrlab demonstrating how Runx proteins accelerate T cell development: nature.com/articles/s41590-0…
Thanks very much also to Golnaz Vahedi @golnaz_v for her kind words and to the three excellent reviewers for their deep understanding of the system and thoughtful, enriching suggestions. Link is: nature.com/articles/s41590-0…
Adorable! But the stamp sheet is way too pretty to use. I guess they want us to buy two, one to keep in a collection.
Go zfish!
NIH zebrafish research included in U.S. Postal Service’s “Life Magnified” stamps | National Institutes of Health (NIH). Got to love a Zebrafish stamp!! nih.gov/news-events/news-rel…
At long, long last!!! HAD to be -- but it's almost been a half-century of deliberate avoidance of looking, don't you think? People still ripping out thymuses at birth -- but Miller & Mitchell wrote in the 1960s - why wasn't this investigated decades ago? Thanks, @ScaddenLab !
There it is, the thymus DOES matter postnatally! Congratulations @ScaddenLab nejm.org/doi/full/10.1056/NE…
@EVRlab retweeted
There it is, the thymus DOES matter postnatally! Congratulations @ScaddenLab nejm.org/doi/full/10.1056/NE…
A reference cell tree will serve science better than a reference cell ... sciencedirect.com/science/ar…
For those of us who are *developmental* molecular biologists, it's great to see this nice commentary in @CellCellPress . Thanks, @JShendure and @sdomcke!
@EVRlab retweeted
Multi-scale reprogramming of chromatin organization underlies immunological memory and dysfunction in human CD4+ T cells @SciImmunology @R_Stadhouders @G_Stik
science.org/doi/10.1126/scii…
@EVRlab retweeted
Excited to introduce scKINETICS, an algorithm for joint inference of gene regulatory mechanism and cellular velocity, co-developed by the amazing duo of @CassBurdziak and @juuuulianaar
academic.oup.com/bioinformat…
@EVRlab retweeted
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Fabulous news! So well-earned, Nina @Nina_CabezasW ! I hope it will be a very happy and rewarding place for you and your lucky students!
🥳 😢 –Wow. @Nina_CabezasW got appointed Full Professor of Stem Cell Biology and Ageing in the Department of Health Sciences and Technology (@ETH_en, Zurich). Congratulations!
And #ThymOz 2023 turned out to be a great meeting! Kudos to all participants and especially thanks to main organizers Ann Chidgey & Daniel Gray.
Six years since the last #ThymOz and 4 years since we met in person at all. Looking forward to seeing my thymus peeps @UobAnderson @MKALabUofT @JoelSpencerLab @evrlab @taghon_t @DrMvandenBrink (and many others).
