HHMI Hanna Gray Fellow & Postdoc with @AndyClarkCornel & @CedricFeschotte at @Cornell | PhD @Caltech | selfish genetic element, TE, small RNA, evolution
Ithaca, NY
Joined December 2018
- Tweets1.2K
- Following262
- Followers443
- Likes1.6K
Pinned Tweet
over the moon to share the news that I got selected as a @HHMINEWS Hanna Gray Fellow 😄 super humbled to join this wonderful community to learn and grow and do cool science!! 🔬🧪🧬 also thanks to so many of my mentors and friends who have supported me along the way 🙏
Today we're thrilled to announce our 2024 #HannaGrayFellows! Please join us in welcoming and celebrating these outstanding early career scientists!
This cohort includes scientists working in research areas ranging from treatment-resistant cancers to sleep dysregulation to how animals evolved to live on land.
Read more about HHMI’s Hanna Gray Fellows Program: hhmi.news/4gIsZU5
Peiwei Chen retweeted
Exciting news! I am launching the Lab of Polymicrobial Interaction & Evolution @IPMBSinica @AcadSinica! 🎉 Our brand-new website is live: labofpie.org 🥧
We’re recruiting at all levels—if you're curious about how fungi and bacteria compete and co-evolve, come join us!
Peiwei Chen retweeted
Certain genes are “selfish," cheating the rules of inheritance to increase their chances of being transmitted. Researchers in @yamashitaflylab have uncovered a unique "self-limiting" mechanism keeping the selfish gene Stellate in check: wi.mit.edu/news/selfish-gene…
thank you @emilianomarti7 @AmLarracuente @TrendsGenetics for taking the time to write such a thoughtful commentary of our recent paper on genome defense @PNASNews @Caltech & articulate the evolutionary implications of our work -- what a treat!! 😆
In a new Trends in Genetics piece, @AmLarracuente and I spotlight an amazing work lead by @peiwei_chen uncovering Trailblazer—a regulatory innovation in the in piRNA pathway to suppress the meiotic driver Stellate. Check it out: authors.elsevier.com/c/1ktQO…
Peiwei Chen retweeted
In a new Trends in Genetics piece, @AmLarracuente and I spotlight an amazing work lead by @peiwei_chen uncovering Trailblazer—a regulatory innovation in the in piRNA pathway to suppress the meiotic driver Stellate. Check it out: authors.elsevier.com/c/1ktQO…
looking forward to sharing my PhD work with @AlexeiAravin @Caltech at #Dros25 tonight & meeting old and new friends throughout the fly meeting 😀
We're excited to announce the 2025 Larry Sandler Award recipient, @peiwei_chen 🎉
This award honors students completing a PhD in Drosophila research. Dr. Chen will present the Larry Sandler Memorial Lecture on evolutionary innovation in genome defense at #Dros25 in March.
1/3🧵
Peiwei Chen retweeted
Congratulations to Peiwei Chen, Ph.D, Caltech 2024!
deeply humbled to receive the Larry Sandler Award, named after the father of meiotic drive
I'd like to think this award belongs to my mentors, colleagues, lab mates, and the wonderful fly community that has supported me & so many others in their journeys #basicscienceFTW
deeply humbled to receive the Larry Sandler Award, named after the father of meiotic drive
I'd like to think this award belongs to my mentors, colleagues, lab mates, and the wonderful fly community that has supported me & so many others in their journeys #basicscienceFTW
We're excited to announce the 2025 Larry Sandler Award recipient, @peiwei_chen 🎉
This award honors students completing a PhD in Drosophila research. Dr. Chen will present the Larry Sandler Memorial Lecture on evolutionary innovation in genome defense at #Dros25 in March.
1/3🧵
Peiwei Chen retweeted
Abstract submission for SMBE2025 in Beijing is open. If you study gene duplication or new genes, please consider submitting an abstract for a talk for Symposium 7, The Origin, Evolution, and Phenotypic Contributions of New Genes. smbe2025.scimeeting.cn/en/we…. Deadline is Jan 30, 2025.
Peiwei Chen retweeted
Centromere evolution isn't a sudden switch!
Our study shows centromere transitions are a step-by-step process driven by a combination of drift and selection. Discover how the kinetochore interface shapes this gradual change in our new preprint doi.org/10.1101/2025.01.16.6… 🧵(1/8)
Peiwei Chen retweeted
FlyBoard elections are open through Feb. 16, 2025. Please look for Genetics Society of America email: Select future FlyBoard leadership! Here is a link to access the candidate statements and ballot: genetics-gsa.org/2025-fly-bo…
Please repost.
#Dros25 @GeneticsGSA
sharing our cover art proposal, which sadly did not make it @PNASNews: an artistic illustration of genetic innovation, where a musician plays the piano and new melodies—represented by small RNAs and scissors-like nucleases—emerge 🎶🎵
check out our paper: pnas.org/doi/10.1073/pnas.24…
ALT Art by Jinglu Midori
happy to share the published version of our work on genome defense against selfish genes 😊 @PNASNews
"Escalation of genome defense capacity enables control of an expanding meiotic driver"
pnas.org/doi/10.1073/pnas.24…
happy to share the published version of our work on genome defense against selfish genes 😊 @PNASNews
"Escalation of genome defense capacity enables control of an expanding meiotic driver"
pnas.org/doi/10.1073/pnas.24…
Peiwei Chen retweeted
We are all born with a genetic lottery. Millions of T cell receptors are what we have with a hope to defend all cancer and viruses. What if that's not enough? Hope our work can give an interesting answer to you. biorxiv.org/content/10.1101/…
Peiwei Chen retweeted
My paper is out!! 🎉
"Opponent control of reinforcement by striatal dopamine and serotonin", @Nature
Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain 🧠
THREAD ⬇️
1/n
Peiwei Chen retweeted
Thrilled to be able to share my PhD work with @FelipeKTeixeira @GeneticsCam
doi.org/10.1101/2024.11.14.6…
Give us a read if you're interested in #ribosome heterogeneity, #devbio & #translationalcontrol 🪰🔬
Peiwei Chen retweeted
Structural duality enables a single protein to act as a toxin–antidote pair for meiotic drive | PNAS pnas.org/doi/abs/10.1073/pna…
&
A meiotic driver hijacks an epigenetic reader to disrupt mitosis in noncarrier offspring | PNAS pnas.org/doi/abs/10.1073/pna…
2 amazing papers! 🤩
Peiwei Chen retweeted
Excited to share our unexpected finding: piRNA pathway designed to protect the genome from invading nucleic acids created a population of selfish small RNAs that have perpetuated themselves for the past hundred million years of mammalian evolution. biorxiv.org/content/10.1101/…
Peiwei Chen retweeted
Exciting news, fellow #Drosophila researchers! Ever wondered about the genome sequence of your lab strain or the balancers? Check out our Drosophila Laboratory Pangenome Database, featuring a growing collection of reference genome assemblies for popular D. melanogaster strains!