@devsiglab

💭Striving to understand how cells communicate with their environment 🔍Focusing on TGF-beta in development and cancer @thecrick 🧑‍🔬Run by lab members

 London, England
crick.ac.uk/research/labs/caroline-hill
Joined December 2018
  • Tweets134
  • Following246
  • Followers622
20Media
Hill Lab retweeted
the Node@the_Node23 Apr 2024
Here's a round-up of recent job adverts on the Node! ▪️Research technician: @CigliolaLab @GabKardon ▪️PhD: @KarenJLiu @Dariloops @smadar_de @RealFany ▪️Postdoc: @CigliolaLab @deMendoza_Alex @devsiglab @LabSpagnoli Browse our jobs board: thenode.biologists.com/jobs/
Screenshot of the Node jobs board

ALT Screenshot of the Node jobs board

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👀What's that? Flies 🪰 on the cover of @Dev_Cell ? (Fish 🐟 too) Congrats @WilcocksonScott on getting the cover, and yet another reason to plug Scott's work! Check out the stocks in @flystocks! cell.com/issue/S1534-5807(22…
https://www.cell.com/issue/S1534-5807(22)X0024-5#fullCover

ALT https://www.cell.com/issue/S1534-5807(22)X0024-5#fullCover

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First Postdoc paper, first 🦓🐟 paper, first journal cover! 🥳 🎶On the fourth day of Christmas, Dev Cell gave to me: An improved Erk biosensor that detects oscillatory Erk dynamics driven by mitotic erasure during early development🎶 cell.com/developmenta...
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Caroline Hill @devsiglab has been a JCS editor since 2020 and handles articles relating to #developmentalsignalling and chromatin/epigenetics. Have a manuscript focussing on one of these topics? Send it our way! bit.ly/3SEPVux
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Online now: An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early development dlvr.it/Sw5sVH
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Want to study ERK dynamics in real time? There's an improved tool to do just that! @WilcocksonScott and @devsiglab's paper is out! We made the fly version of Scott's new construct. Read about it here, and get the fly stocks @flystocks (#95284-8)! authors.elsevier.com/sd/arti…
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For all your Erk-related needs, we have the reporter for you! And it’s out now! Big thanks to Luca, Pablo, @AmoyelLab and @devsiglab cell.com/developmental-cell/…

An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early...

Wilcockson et al. describe the development of an improved Erk-specific kinase translocation reporter (modErk-KTR). Live imaging of Erk dynamics in zebrafish and Drosophila embryos shows that Erk...

cell.com
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Read about the latest in TGFβ signalling in cell fate regulation: from embryonic development through to tissue homeostasis and disease @devsiglab go.nature.com/3P7Fwp2
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Our latest #NRMCBReview is now online! Louise Richardson, @WilcocksonScott and Luca Guglielmi (now @MRC_LMB) from the Hill lab (@devsiglab @thecrick) discuss TGF-beta signalling in cell fate regulation: 🔗go.nature.com/3P7Fwp2
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Submissions in Journal of Cell Science are handled by expert Academic Editors. From cell signalling, cell migration, cell adhesion, and cell division, through to cancer cell biology, immunology, mechanobiology and more, our team of research-active academics covers a range of topics and is supported by an international Editorial Advisory Board. We also show a strong commitment at first decision, with over 95% of invited revisions being accepted for publication. Find out more at bit.ly/3Wyg1PE
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Want Erk-cellent representation of Erk signalling dynamics? @WilcocksonScott and colleagues from @AmoyelLab & @devsiglab explore an improved biosensor that faithfully reports Erk activity without being impacted by Cdk1. First #preLight from @Kobayashi1S: prelights.biologists.com/hig…
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Hill Lab retweeted
Taponlab@taponlab7 Nov 2022
Erk-cited (excited) about the new work from our @devsiglab colleagues !!!
James Briscoe@briscoejames7 Nov 2022
New from my @TheCrick colleagues in @devsiglab lab Improved Erk-Kinase biosensor w/o off target response to Cdk1 Shows Erk activity transiently extinguished during mitosis, which introduces signaling heterogeneity into an asynchronously dividing tissue biorxiv.org/content/10.1101/…
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New from my @TheCrick colleagues in @devsiglab lab Improved Erk-Kinase biosensor w/o off target response to Cdk1 Shows Erk activity transiently extinguished during mitosis, which introduces signaling heterogeneity into an asynchronously dividing tissue biorxiv.org/content/10.1101/…
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#ZebrafishJobs (cont.) by @LangenauLab 🇺🇸 (Postdoc) - Contact directly langenaulab.com @devsiglab 🇬🇧 (Postdoc) crick.ac.uk/careers-study/va… @JuliaHorsfield 🇳🇿 (Postdoc) otago.taleo.net/careersectio… 19/27
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Caroline Hill @devsiglab gives dynamic keynote address with historical perspective on progress in the TGF-beta signaling field to close out #TGFSRC22 @FASEBorg
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#IZFC2022 Come by and see how I’ve been messing around with a live reporter of Erk activity to improve its specificity at poster 58A (session II), plus find out about the role of mitotic erasure of Fgf/Erk signalling in the developing mesendoderm at poster 49 (session III)
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The Hill lab (@devsiglab) is looking for a post doc to help us decipher the role of Tgfb signalling in cancer! If you are interested (or know someone that might be) apply here crick.ac.uk/careers-study/va… .
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Check out our 'First person' interview with Davide Martino Coda @davide_coda on work he performed @devsiglab @TheCrick, investigating the factors that regulate epigenetics and transcriptional programs : ow.ly/wche50J3Bq9
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Thanks to @J_Cell_Sci for interviewing me for their First Person series! I talked about the eureka moments of the project just published with @devsiglab, and I shared some thoughts about my journey in science so far…👇🏼 journals.biologists.com/jcs/…
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Hill Lab retweeted
FASEB
@FASEBorg20 Apr 2022
Register today for our TGF-ß Superfamily Conference: Signaling in Development and Disease, July 17-21 in Malahide, Ireland. Keynote speakers will be Joan Massagué @MSKCancerCenter, Caroline Hill @TheCrick, and Michael Elowitz @Caltech. bit.ly/3JJN6QL #TGFSRC22
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