@danIsomLab

We uncover how cells sense, communicate, and exchange material, with a focus on pH sensing, intercellular communication, and the dark proteome.

 Miami
isomlab.com
Joined August 2019
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Snuck onto the cover of Nature. Not a bad place for a “superdark” protein to end up. Very grateful. Much deserved Kyutae Lee, Sam Taylor, PhD, Jennifer Arcuri, Ph.D., Shraddha ChandThakuri, Bruno Colon, Jacinda Pujols, and others.
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Out online today in @Nature. The known protein universe holds hundreds of millions of members, yet most remain unexplored, a vast biological darkness that may hold important clues to human health and disease. We went looking in it. doi.org/10.1038/s41586-026-1…
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7th MCP Retreat ✔️ “Colab in the Cays” | Florida Keys 53 talks. 15+ labs. Every participant presenting. Two days of deep science, new connections, and serious inspiration.
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⁦@TackleCancer⁩ looks like Copenhagen. Amazing!
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Pre 5K ⁦@TackleCancer⁩ ⁦@SylvesterCancer⁩ ⁦@univmiami⁩ ⁦@Pap_Corps⁩
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Thank you for the delicious birthday cake, Shraddha (the DAPI staining on the cells was spot on!), and gifts from Jen, Jacinda, Sam, and Kyutae❤️ Who doesn't love purple owls?
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⁦@MayorDaniella⁩, this resilient elderly woman struggling to make it down the stairs because the elevator (visible) and down escalator at Dadeland South are broken. ⁦@FixMetroMDT⁩ ⁦@iheartmiami305⁩
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Replying to @MayorDaniella
@MayorDaniella: this morning at Dadeland South. I didn’t take a photo of the disabled man arguing with security because he couldn’t get up the stairs. I am sure there is cc video of that if you want to see it. @FixMetroMDT @iheartmiami305
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Well said.
BryanRoth
@zenbrainest13 Jan 2025
Cryo-EM structure of an activated GPR4–Gs signaling complex nature.com/articles/s41467-0…

Cryo-EM structure of an activated GPR4–Gs signaling complex

Nature Communications - The proton-sensing GPCRs detect extracellular low pH and regulate diverse physiological responses. Here, the authors report cryo-EM structures of GPR4, which provide insight...

nature.com
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In my excitement for his visit, I forgot to get a selfie with Henrik. This will have to do 😂😂!
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