@codingdilara
 Amsterdam, The Netherlands
Joined July 2020
  • Tweets58
  • Following442
  • Followers48
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Dilara A. retweeted
Salta Lab@LabSaltaApr 24
Very excited & proud to share our new paper, now published in @CellStemCell!🧠🌱👇 Excited about all the discussions we invite with our work & proud of our incredibly ‘resilient’ team (spearheaded by @georgietos) and an outstanding group of collaborators who made this possible💜
Cell Stem Cell@CellStemCellApr 24
Online Now! Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer’s pathology and cognitive resilience dlvr.it/TSCQSH #stemcells

Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer’s pathology...

Tosoni and colleagues identify immature neurons in the aged human hippocampus with signatures of younger biological age and cellular fitness. Their molecular programs and intercellular interactions...

cell.com
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Our paper is now live on bioRxiv! 🤩@georgietos has done an amazing job breaking it down in this thread. Take a look!🥳
Giorgia Tosoni@georgietos10 Jan 2025
🧵 1/ Excited to share our new research on immature neurons (ImN) in the adult human brain and their roles in healthy aging, Alzheimer’s disease (AD), and cognitive resilience. Here’s what we discovered 👇
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Amsterdam, #Pint24 is coming for you in a few weeks! 🧠 🪴⚕️Leading researchers will present research on neuroscience, plant systems and immunology! Come along to the #PintNL events at your local pub to learn more. Tickets available now 🎟️
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Dilara A. retweeted
Salta Lab@LabSalta6 Nov 2023
Come join us! 🧠🧑‍💻
NIN@NIN_knaw6 Nov 2023
Internship alert! 🧠💼 Check out our new Computational Master internships involving single cell analysis of human hippocampal neurogenesis in relation to Alzheimer's Disease👇 herseninstituut.nl/stages/co… #research #internship #brain #neuroscience #lab #hippocampus
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simpleaf : A simple, flexible, and scalable framework for single-cell data processing using alevin-fry. #SingleCell #DataProcessing #Rust #Bioinformatics @nomad421 academic.oup.com/bioinformat…

simpleaf: a simple, flexible, and scalable framework for single-cell data processing using alevin...

AbstractSummary. The alevin-fry ecosystem provides a robust and growing suite of programs for single-cell data processing. However, as new single-cell tech

academic.oup.com
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Dilara A. retweeted
Cell@CellCellPress28 Sep 2023
The new issue is out! Just in time for #WorldAlzheimersMonth, Cell features four articles that together demonstrate the genomic, epigenomic, and transcriptomic dysregulations underpinning Alzheimer's disease at single-cell resolution across cell types. To read more click here👉cell.com/cell/current
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Ever analyze a scRNAseq dataset and wonder if a specific cell state has been seen before? And if so, where in the human body? Under what conditions? Well, now you can use our lightning fast SCimilarity search and foundational model for that! ⚡️🔎🧬 biorxiv.org/content/10.1101/… (1/11)
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What is a cell type? What is cell state? in the single-cell era, 4 papers discussing this topic 👇 🧵
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10 benchmark papers on single-cell data 👇 🧵
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Happy to share our recent work now published in @iScience_CP. Great collaborative effort between Amsterdam 🇳🇱 (@LabSalta ) and Leuven 🇧🇪(@DeStrooperLab). sciencedirect.com/science/ar… A thread 🧵
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Gene regulatory networks (GRNs) are useful models to understand cellular identity and disease. We have reviewed the GRN inference field in the current era of single-cell multi-omics 📖 out in @NatureRevGenet 🔗doi.org/10.1038/s41576-023-0… Full-text access: rdcu.be/dfpa2
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Dilara A. retweeted
Salta Lab@LabSalta24 May 2023
📢Really looking forward to sharing our latest research on #AdultNeurogenesis in #HumanBrain this September!! 🧠🌱 Chaired by Gerd Kempermann @CRTDpress @DZNE_de, organized by @abcam 👇🏾 abcam.com/events/adult-neuro… #progresshappenstogether #Alzheimers #regeneration #neuroscience
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Only 7 days before #pint23!✨ 🐝🧪👩‍🔬📚🔬👓🧠🐟🫀💫🥼👨‍🔬🔭🧫🦴 🗓️22nd-24th May 2023 🗺️26 countries 📍400 cities/towns around the world All the information : pintofscience.com/
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Read this new Special Issue on adult #neurogenesis in the #Hippocampus. 👇 @HasselmoMichael Included articles and reviews highlight current developments in the field. See for yourself: ow.ly/kUA350NAL7f
Hippocampus - Special Issue: Adult Neurogenesis in the Hippocampus - Available now. Image shows journal cover.

ALT Hippocampus - Special Issue: Adult Neurogenesis in the Hippocampus - Available now. Image shows journal cover.

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Incredibly proud to see our benchmark of single-cell preprocessing methods finally published 🥳🥳🎉 We show that despite its theoretical limitations, no other transformation consistently outperforms log(y/s+1). All details at nature.com/articles/s41592-0… and github.com/const-ae/transfor…
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Dilara A. retweeted
NIN@NIN_knaw3 Apr 2023
Is our brain able to regenerate? And can we harness this regenerative potential during aging or in neurodegenerative conditions? A new study shows why there are conflicting results and proposes a roadmap on how to solve these issues. nin.nl/news/how-do-we-know-i…
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I am very proud to share our recent publication: "Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: reconciling controversy or fueling the debate?" Check @georgietos's thread out! 🥳
Giorgia Tosoni@georgietos3 Apr 2023
☕️ Fresh out of the press in @NeuroCellPress!! Happy to share our manuscript “Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: reconciling controversy or fueling the debate?” @LabSalta @NIN_knaw cell.com/neuron/fulltext/S08… 🧵1/n

Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: Reconciling contro...

Tosoni et al. probe the challenges related to the design, analysis, and interpretation of single-cell transcriptomic studies in the adult human hippocampal neurogenic niche and propose a series of...

cell.com
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We've been working on Seurat v5 for two years and are excited to share it with you soon! In a webinar w/@10xGenomics and @ScienceMagazine on 3/29, I'll introduce new methods to analyze spatial/multimodal datasets that scale to tens of millions of cells: view6.workcast.net/register?…
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I need to raise awareness about an important point in #scRNAseq data analysis, which, in my opinion, is not acknowledged enough: ‼️In practice, most cell type assignment methods will fail on totally novel cell types. Biological/expert curation is necessary! Here's one example👇
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🧠We are trying to make a big list of all the coolest #neuroscience conferences ✍️. Please, comment below to tell us some of your favorite conferences you attend❤️! If you know the dates for the next one, we'd love to hear that too. #neurotwitter #AcademicTwitter #AcademicChatter
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