Daniela retweeted
When writing, I recommend the 20-20 rule: 20 minutes of writing followed by 20 weeks doing new, unrelated projects you won't finish
Daniela retweeted
My lab has been working for the past 15 years to develop a method to isolate specific genomic loci to identify its chromatin composition & protein interactome. Finally,… our superb physician/scientist Dr. Bercin Cenik @bkcenik did it and here it is cell.com/molecular-cell/full… Not only was she able to develop this method, which she calls TurboCAS, she was able to identify known & novel regulators of heat shock & Myc expression. Cannot wait to see what Bercin and TurboCAS will discover about the molecular basis of transcriptional regulation with great impact on clinic in the next few years! @NU_BMG_SQE @NUFeinbergMed @MolecularCell
Daniela retweeted
One small step for X-inactivation, one giant leap for
@theNestorLab. So happy that our first paper on XCI is out in @NatureComms. A study into human T-cell development took a wild turn when we found one female was fully skewed for XCI! nature.com/articles/s41467-0…
Daniela retweeted
Our latest out today @Nature!
We revisit a century-old theory and show that metabolic gradients work hand-in-hand with genetic&signalling instructions to shape the embryo. Glucose isn't just an energy source, it acts as a major conductor of the body plan🍬
nature.com/articles/s41586-0…
Daniela retweeted
New REVIEW from our lab sciencedirect.com/science/ar… @agata_kalita summarized beautifully the current knowlege on #dosagecompensation in non-model insects 🦋🦟🐞🦗🪰🪲🪳
Daniela retweeted
MAYEX is an old long noncoding RNA recruited for X chromosome dosage compensation in a reptile | Science science.org/doi/10.1126/scie…
Daniela retweeted
One of the X chromosomes in females is silenced with a microscopically distinct chromatin configuration. Happy to share our latest work on deciphering how the X chromosome folds during its inactivation for the first time in mouse female embryos!
nature.com/articles/s41588-0…
Daniela retweeted
🚨Preprint alert🚨 Excited to share the #preprint version of our work @MundlosLab ! Curious about how a transposable element (TE) insertion can cause developmental phenotypes? 🧬🦠🐁
Check the 🧵 below and the full version on BiorXiv:
biorxiv.org/content/10.1101/…
Daniela retweeted
Compensation of gene dosage on the mammalian X
In this Review, @cecalev, Beatriz Viçoso & @rafaelgalupa discuss classic and recent hypotheses, observations and mechanisms regarding X-chromosome upregulation and X-chromosome inactivation in mammals:
journals.biologists.com/dev/…
ALT Figure 1: Balancing the scales: the choreography of upregulation and inactivation of the X chromosome during mouse embryonic development.
Daniela retweeted
Don't miss Daniela Cecalev @cecalev's review on "Compensation of gene dosage on the mammalian X" together with Beatriz Viçoso and myself, for a comprehensive look into X upregulation and inactivation! ⬆️⬇️
journals.biologists.com/dev/…
With support from @FRM_officiel and @laliguecancer
Daniela retweeted
It was a pleasure to write this review together with @nellykanata and Rachel Duffie @sneexish from the Lomvardas lab on the principles that govern monoallelic expression of olfactory receptors and Xist for @Dev_journal
Establishment and maintenance of random monoallelic expression
In this Review, @nellykanata, @sneexish & @EddaGSchulz @MPI_MolGen give an overview of the regulatory mechanisms and current models for establishment and maintenance of monoallelic expression:
journals.biologists.com/dev/…
ALT figure 2: The establishment of monoallelic Xist expression.
Daniela retweeted
How hard is it to do science in a language that’s not your first language? We quantified the severity of #languagebarriers for non-native English speakers when reading/publishing papers and attending/presenting at international conferences.
doi.org/10.1371/journal.pbio…
1/9
Daniela retweeted
Celebrating #CasTuner with my lovely labmates @EddaGSchulz @nellykanata @jjfroehlich @TSchwammle @elodie_lorentz @cecalev @JadeScouarnec @bothe_melissa @Alexandra Martitz and Ilona Dunkel! Glad to have you! 🌈🏄🌄🍻
Daniela retweeted
CasTuner - our tool 🛠️ to tune endogenous gene 🧬expression: Now out in a peer-reviewed version @NatureComms
Now tested on additional targets, in human cells and on physiological phenotypes.
Congratulations🍾 @GemmaNoviello who performed ALL experiments!
nature.com/articles/s41467-0…
Ever wished to tune endogenous gene expression @ single cell level? Now you can! With #CasTuner : a degron and CRISPR/Cas-based toolkit for analogue tuning of endogenous gene expression. New preprint out! With @EddaGSchulz @RutgerGjaltema @MPI_MolGen biorxiv.org/content/10.1101/…
Daniela retweeted
Wise words from Rabindranath Tagore.
Tagore was awarded the 1913 Nobel Prize in Literature for his sensitive, fresh and beautiful poetry expressing his poetic thought.
Learn more about Tagore: bit.ly/2GgTIs0
#Tagore160
Daniela retweeted
How it started: How it’s going:
ALT First image of Earth from a U.S. satellite, Explorer VI, looks like a white smudge on a black background
ALT Full disk satellite image of Earth, taken from one million miles away at L1, oriented over the Pacific Ocean
Daniela retweeted
We know many of you are home and the walls are closing in.
So... get to know the World Digital Library: free access to thousands of books, documents & photos from all countries and cultures.
Check it out here ➡️wdl.org/en/
#QuarantineLife #StaySafe #COVID19
