I like asking questions.
Birmingham, AL
Joined May 2022
- Tweets42
- Following93
- Followers63
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Brittany Curtiss retweeted
So exciting to see our work featured by @MCR_AACR ! Very nice work by a talented duo in the lab @will_yashar and @bmcurtiss!
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Brittany Curtiss retweeted
I usually don't post this kind of stuff, but I wanted to share a brief thread on the value of community:
Brittany Curtiss retweeted
FLT3 mutations are common in acute myeloid #leukemia (#AML). @will_yashar et al. show that LSD1 inhibition enhances and FLT3 inhibition by disrupting the MYC blood super-enhancer—
bit.ly/3HyMe2T
@bmcurtiss @DanColeman83 @jake_vancampen @OHSUKnight
This was such a neat project to work on! Amazing job bringing it all together @will_yashar 👏
Our work on the mechanism of dual FLT3 and LSD1 inhibition has been released in print by @MCR_AACR! Follow this link to check it out: aacrjournals.org/mcr/article…. #Leukemia #AACR23 #AcademicTwitter
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Brittany Curtiss retweeted
New paper out this week from talented @OHSUKnight graduate student @BreannaManiaci_! (1/x)
haematologica.org/haematolog…
Brittany Curtiss retweeted
End of the year win for GoPeaks: 500+ downloads after 5 months post-publication!
Download GoPeaks to call sensible peaks in your CUT&RUN/CUT&Tag/ATAC-Seq data. Hope it continues to serve you throughout 2023!
#Bioinformatics #Genomics
Brittany Curtiss retweeted
Excited to share a new paper out today in Leukemia from @DrTedPBraun and a great collaborative team from @ohsuknight and CEDAR! A few years back, we noticed that there was a high proportion of ASXL1 mutations in neutrophilic leukemias. (1/x)
nature.com/articles/s41375-0…
Brittany Curtiss retweeted
Hot off the press! Collaborative work from @DrTedPBraun’s and @juliamaxson’s groups describing the mechanism of ASXL1 deletion in granulocyte progenitors. nature.com/articles/s41375-0… #HemeTwitter
Brittany Curtiss retweeted
1/6 Very excited to announce sciMETv2 for high-throughput robust single-cell DNA methylation analysis led by @oconnellphds out in @NatureComms!
#SingleCell @OHSUBrain @OHSUKnight @OHSUNews @OHSUSOM #epigenetics
rdcu.be/c1kdp
Brittany Curtiss retweeted
Excited to share that my review article "EGFR, the Lazarus target for precision oncology in glioblastoma" has been published online. Special thanks to everyone that helped put together this comprehensive review on EGFR in GBM.
academic.oup.com/neuro-oncol…
I'm excited to be a professional question asker... Discovering more about the wonders of humanity while bringing healing to patients. Thanks to all who continue to support me along the way.
@UABMSTP @UABHeersink
And thank you @britneycoreymd
for the wisdom you imparted on us during white coat!
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Brittany Curtiss retweeted
CITEViz is one of the newest projects coming from the @juliamaxson and @DrTedPBraun lab!
We made a single-cell viz platform that replicates the interactive flow cytometry workflow in CITE-Seq data (via R-Shiny). We'll demo it Friday 3:30 PM at #bioc2022
🧵below
Brittany Curtiss retweeted
Excited and honored to share this essay with the world.
Thank you @JAMA_current for the opportunity to share my story and the incredible editorial support.
jamanetwork.com/journals/jam…
Glad to be a part of this team!
GoPeaks, from Yashar, @KongGarth, @jake_vancampen, @bmcurtiss, Braun & co, for calling peaks in CUT&Tag data, specifically for histone modifications which can have a range of different peak profiles, and a low background signal. genomebiology.biomedcentral.…
ALT Schematic of how GoPeaks assigns peaks based on read density in consecutive bins
Brittany Curtiss retweeted
Small win today, #GoPeaks passed its first 100 downloads 🙌Take a look at our peak caller designed for sparse #epigenetic data such as #CUTnTag!
biorxiv.org/content/10.1101/…
I'm stoked to share this work! I am thankful to work with such a great team.
Excited to announce the first paper out of the Braun Lab! nature.com/articles/s41375-0…. @bmcurtiss and team demonstrated the efficacy of dual KIT and LSD1 inhibition in AML, identifying changes in MYC and PU.1 dynamics as the mechanism of action of the drug combination.
Brittany Curtiss retweeted
Delighted to share a new manuscript in @BloodJournal from the incomparable @SarahCarratt and team! @KongGarth @schonrockz @BreannaManiaci_ @blaylock_hunter @BarisAdrian @DrTedPBraun (1/x)
ashpublications.org/blood/ar…