
Quantitative immunology & biological physics. Q-Immuno Lab PI @iit_ucl & @ucl_ipls past: Lewis-Sigler Fellow @Princeton, PhD @ENS_ULM Also @qimmuno.bsky.social
London, UK
Joined February 2014
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Andreas Tiffeau-Mayer retweeted
The Sim lab has been hard at work and we’re proud to present our first paper.
We developed new methods to study peptide:KIR interactions.
Congratulations to star postdoc Tanusya Murali who led the project.
biorxiv.org/content/10.64898…
Andreas Tiffeau-Mayer retweeted
We are #absolutely #thrilled to #present @ImmunityCP - Deep profiling of human T cells defines compartmentalized clones and phenotypic trajectories across blood and tonsils: Immunity cell.com/immunity/fulltext/S…
Andreas Tiffeau-Mayer retweeted
BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
Andreas Tiffeau-Mayer retweeted
Driven to understand why transplants fail, @andimscience used a @UCL – @Sydney_Uni Strategic Ignition Grant to collaborate with @AFSharland to combine their computational and clinical expertise⬇️
bit.ly/3VZ0tF4
Andreas Tiffeau-Mayer retweeted
We have been fortunate to have a stream of extraordinary Fellows as part of our community. They have gone on to wonderful positions .. It is time, once more, to renew. Our annual search is a chance for us to understand what the brightest young people in the community are doing!
Andreas Tiffeau-Mayer retweeted
Wigner's surmise in biophysics? Maybe!
Pankaj Mehta (BU) and I wrote this perspective arxiv.org/abs/2509.03765
Andreas Tiffeau-Mayer retweeted
Paper from me @michecurtis @soumya_boston and co out now in @naturemethods! We now call the tool starCAT instead of *CAT but the strategy is the same: Build a catalog of ~50 interpretable T cell gene expression programs + use them to interpret new data nature.com/articles/s41592-0…
Replying to @michecurtis
@michecurtis and I are thrilled to share our preprint "Reproducible single cell annotation of programs underlying T-cell subsets, activation states, and functions" from the @soumya_boston lab @BrighamResearch and @broadinstitute!
biorxiv.org/content/10.1101/…
1/12
Andreas Tiffeau-Mayer retweeted
1/ 🧵Can protein language models reason about evolution, not just model it?
We built a 24 M-param PLM, Phyla, that reconstructs phylogenetic trees better than existing PLMs.
Details & links in 2/👇
Andreas Tiffeau-Mayer retweeted
#posting this again if any #postdoc candidates are interested in digging deep into #TCR #Crossreactivity #Tcell functional studies in #autoimmunity and #cancer -please contact me!
Anticipating #new #funding -our lab is seeking #postdocs with #expertise in #Tcells #TCRs #crossreactivity #molecularbiology #protein #production Please #email #RT -start date flexible, end of #2025 or beginning of #2026
Andreas Tiffeau-Mayer retweeted
A legendary lineup of speakers this week at the Antwerp T cell receptor (TCR) conference! Thanks to the organisers and everyone with whom I had conversations. Enjoyed discussing our group's latest algorithms for TCR repertoire profiling! Latest version: github.com/innate2adaptive/D…
Andreas Tiffeau-Mayer retweeted
We’re hiring! Exciting #ResearchAssistant opportunity @sheffieldUni using #zebrafish models to study host #immuneresponses to bacterial infection👇
Apply here: tinyurl.com/52rdmj4e
Andreas Tiffeau-Mayer retweeted
🚨Postdoc position available in the Fink lab🚨
At the Pears Building (Div. of Infection & Immunity UCL)
The Fink lab (Douglas Fink) is investigating the role of anti-cytokine auto-antibodies in immune dysfunction and disease during ageing: lnkd.in/ez9y4app
Andreas Tiffeau-Mayer retweeted
Less than a week left to submit abstracts for the 3rd London Quantitative Immunology Day! qimmuno.com/ldnday/.
Register and share your work with a diverse set of biologists, physicists, mathematicians all united by a common interest in immunology.
@UDemael
Andreas Tiffeau-Mayer retweeted
check out our new manuscript (led by @GMarcoVisani)
structure-based machine learning model for TCR-pMHC complexes, predicting T-cell affinity to peptide-MHC complexes, quantifying T-cell receptor specificity, and designing de-novo immunogenic peptides:
arxiv.org/abs/2503.00648
Andreas Tiffeau-Mayer retweeted
🚀 Exciting Announcement: Monthly Webinar Series 🚀
I am delighted to launch our new monthly webinar series:
🔬 Unravelling T Cell Recognition: Insights from Immunology and AI
Andreas Tiffeau-Mayer retweeted
Registration and abstract submission to #ATCR2025 are now open! Join world-renowned experts to discuss everything #Tcellreceptor related. #immunology @airr_community @biominaBE
uantwerpen.be/atcr2025
Andreas Tiffeau-Mayer retweeted
Starting the year with a brand #NOA from #NIAID #NIH and funding from Cure Alz Fund -if anyone would like to join as a #postdoc in our lab, please let me know -#TCR #structure #function and #crossreactivity
Andreas Tiffeau-Mayer retweeted
Two very exciting roles in this brilliant group. The deadline for one is next week, the other the end of January, so get applying and do some work that really matters with excellent people!
📣 We are hiring! Postdoc opportunity in Quantitative Immunology @ucl.
🔬 Develop computational approaches to discover clonal and functional T cell determinants of protection against Tuberculosis. Fully funded 2-year position.
🗓️ Apply by Dec 10
ucl.ac.uk/work-at-ucl/search…
Andreas Tiffeau-Mayer retweeted
Come work with me! Two fully-funded PhD positions in Theoretical Physics of Living Matter are available in my group at UCL, in the wonderful city of London . For more information and to apply, visit agudo-canalejo.com/work-with…
Andreas Tiffeau-Mayer retweeted
🚨Paper alert 🚨Fundamental limits on predicting T cell specificity from partial receptor sequence matches to known binders pnas.org/doi/10.1073/pnas.24… @iit_ucl @Focis_FCE @andimscience @PNASNews



























