🦠 PhD candidate @UCL & @MGHNeurosurg 🦠 // co-md & venture fellow @NucleateUK// @join_polaris //previously @UniofOxford & @HOLOBIONT_ //Immunology & Biotech ✨
Joined March 2021
- Tweets130
- Following754
- Followers244
- Likes731
Ursule Demaël retweeted
Cohere just launched its first multimodal LLM.
My team and I built it—check it out!
cohere.com/blog/command-a-vi…
It beats OpenAI GPT 4.1, Meta Maverick 4, Pixtral Large, and Mistral Medium 3 models on most important benchmarks.
Ursule Demaël retweeted
Less than a week left to submit abstracts for the 3rd London Quantitative Immunology Day! qimmuno.com/ldnday/.
Register and share your work with a diverse set of biologists, physicists, mathematicians all united by a common interest in immunology.
@UDemael
Ursule Demaël retweeted
As a happy end of year post 🌲🎆 I'm delighted to share I've been awarded a @RoyalFreeChty ECR grant! I'll be studying the clonality of T cells in fascioscapulohumeral dystrophy. Huge thanks @BennyChain, @iit_ucl, and collaborators at Queen's Square and King's College. 🙏
To anyone looking for a PhD in computational immunology, check this project out! Andreas leads an incredible group and is an amazing supervisor!! ⭐️
@andimscience
qimmuno.com/openings/
Ursule Demaël retweeted
Join us on the latest Nucleate Podcast with Luke Timmerman (@ldtimmerman), award-winning biotech journalist and founder of @timmermanreport!
Listen to the full episode on Signal: signal.nucleate.xyz/biotech-…
Ursule Demaël retweeted
Information theory of the T cell receptor sequence-function map -- our paper now out @PNASNews ! 🔥
How informative (in bits) is the α or β chain? When does partial information limit predictions? + insights into synergy, Renyi entropy, optimal compression & more 👉
ALT https://www.pnas.org/doi/10.1073/pnas.2408696121
Super excited to release this short movie about our group, the Stauss Lab at UCL's Institute of Immunity and Transplantation🧪🔬
Our research aims to engineer T cells against cancers and autoimmune diseases
Huge thanks to Charlie Yuille and his team at CHIK for the film!
Three years today since we moved into the Pears Building! 🎊 To mark this, we've just launched a new film celebrating some of the fantastic scientists from the Stauss Lab here at the Institute 🎬
buff.ly/3XKAEZV
#Immunotherapy #TCells #CancerResearch #AutoImmuneDisease
Ursule Demaël retweeted
Join us at MGH/HMS for a postdoc! We’re recruiting computational biologists to analyze scRNA-seq, spatial transcriptomic, and bulk genomic data from diverse cancer types. More info here: pettilab.mgh.harvard.edu/hom…
Please RT!
Had an incredible time at the Nucleate 2024 Summit in Santa Cruz (CA)🌞🌲 @NucleateHQ
Learnt so much from incredible keynotes including Rick Klausner from @NCI @Altos_Labs (and many more), @tkalil2050 , Alexander Titus at @DeptOfDefense and @ilangur from @ARIA_research
This closes months of a VC fellowship where 5 of us have interviewed and diligenced the top of the 162 biotech companies participating in the @NucleateHQ Activator.
@kulesatony and @jbpin90 were incredible mentors in this process!
If you're interested in getting in touch, supporting, or investing in our brilliant Activator companies, reach out!
...as always Nucleate events always leave me so proud of the people I get to work with- massive congrats to the whole team for an excellent Summit @NucleateHQ
Ursule Demaël retweeted
How to pre-train protein language model to optimize transfer learning? @YutaNotUtah’s PhD work shows prior PLMs struggle to predict TCR specificty & uses contrastive learning to overcome this limitation. 👉arxiv.org/abs/2406.06397
Ursule Demaël retweeted
Martina's elegant new paper defines an important and under-appreciated role for molecular interactions between CDR loops of the TCR !
Intra- and inter-chain contacts determine TCR specificity: applying protein co-evolution methods to TCRαβ pairing biorxiv.org/cgi/content/shor… #biorxiv_immuno
Purity is also not the criteria by which scientists judge "good" science
"If we study the criteria that underlie a scientist's own valuation of science, we shall certainly not find purity among them"...
...one last snippet I loved is him marvelling at the diversity of function of biological macromolecules:
"They insulate, they fill out, they fetch and carry, they prevent the Organism as a Whole from falling apart or from dissolving in water, they prop up, they protect..."
...we have developed a thwarted view of the superiority of "pure" research detached from intended use or application
The view is that useless = good