@mike-od.bsky.social We study the behavioral effects of commensal microbes on the worm, C. elegans @MCDB_Yale. Join me! (he/him)
New Haven, CT
Joined January 2012
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I'm thrilled to share our new preprint, in which we've found that neurotransmitters can be chemically "marked" as a way to incorporate metabolic history - such as diet or life stage. biorxiv.org/content/10.1101/… Led by Porhathai "Un" Malaiwong, Allen Schroeder and Tia Brown. 🧵(1/6)
For the worm-types, the destination of the glucose-octopamine complex is CAN - whose function is essential but not well understood. CAN appears to have the capacity to release octopamine but not to make it itself, implying it acts like a neuron under certain circumstances. (5/6)
Mike O'Donnell retweeted
MCDB at Yale is seeking to fill a tenured Associate/Full Professor position. Candidates with interest in investigating outstanding questions in biology at the organismal, cellular or molecular level are encourage to apply.
Apply at buff.ly/3NG6uSQ
Mike O'Donnell retweeted
a personal update: in January, I'm moving to Yale to join @MCDB_Yale and to open my lab in the @WuTsaiYale Institute!
We will investigate multicellular self-organization using synbio tools to read and write developmental signals in stem cell models.
syndevbio.org/
Mike O'Donnell retweeted
Our work on PPP2R3C-MAP3K1 at centrosomes is now out in @CurrentBiology! authors.elsevier.com/a/1jpcA…. Now with more functional analyses (lethality of PPP2R3C KO or FOP KO is suppressed by MAP3K1 KO) and more beautiful U-ExM expansion microscopy by @Armanduuum and @CentrioleLab!
Excited to share our preprint on a new centriolar kinase-phosphatase module, with fantastic U-ExM microscopy by @CentrioleLab and @Armanduuum! biorxiv.org/content/10.1101/… Here we studied Ppp2r3c, a PP2A phosphatase regulatory subunit and hit from our prior cilia CRISPR screen…
Mike O'Donnell retweeted
Check out this beautiful work by my former lab mate @JakeCarrasquil1 in the @BahmanyarLab 👏 Includes many cool findings on how CTDNEP1 and binding partner NEP1R1 regulate lipid synthesis at the ER and nuclear envelope! ✨👇
From MBoC
Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage @bahmanyarlab
doi.org/10.1091/mbc.E23-09-0…
Mike O'Donnell retweeted
A three-dimensional immunofluorescence atlas of the brain of the hackled-orb weaver spider, Uloborus diversus. biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mike O'Donnell retweeted
Postdoc position alert - in Alex Cantó-Pastor's NEW lab at Yale. While we will miss him greatly, a new postdoc will be sure to benefit from his mentorship and will get to participate in a very exciting project at the intersection of development and immunity. @acantopastor
Mike O'Donnell retweeted
May is Ehlers-Danlos Syndromes & Hypermobility Spectrum Disorders Awareness Month! As a disabled PhD student I wanted to remind others that 1 in 6 people worldwide – experience disability, -and 80% of those people are considered to have an "invisible" disability!👩🏻🔬@TheEDSociety – at New Haven, CT
Mike O'Donnell retweeted
Excited to share our preprint on a new centriolar kinase-phosphatase module, with fantastic U-ExM microscopy by @CentrioleLab and @Armanduuum! biorxiv.org/content/10.1101/… Here we studied Ppp2r3c, a PP2A phosphatase regulatory subunit and hit from our prior cilia CRISPR screen…
Mike O'Donnell retweeted
Hesitating whether to attend? Don’t!! Register and join the friendly C. elegans Neuro Community in Madison, WI. Retweet if you can!
conferences.union.wisc.edu/c…
Mike O'Donnell retweeted
Thank you to @CellChemBiol for the opportunity to write this! It was fun to put to paper and maybe it'll resonate with some folks. Shoutouts to @StanfordBiochem @RohatgiLab and @UChiChemistry, and also my dad who can now cite a paper in which I say 'My father was right' 😆
Stories: Combating the myth of “innate genius” in science by Sigrid Nachtergaele @SiggyN5 at @MCDB_Yale @YaleCancer @YaleMed
dlvr.it/T4QF2w
Mike O'Donnell retweeted
Function of C. elegans neurons from synaptic connectivity biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mike O'Donnell retweeted
Recruiting a research tech to join the growing Hilbert Lab @BiologyBC ! We're looking for curious scientists to help us build a supportive research environment and tackle adventurous new projects investigating host-fungal interactions. Apply: tinyurl.com/ev8bx7au
Please RT!