@VandyAtVandy

Bio Statistics

 Philadelphia, PA
simonvandekar.bitbucket.io/
Joined October 2017
  • Tweets258
  • Following217
  • Followers262
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Terrible stuff happening in downtown Nashville
The Tennessee Holler
@TheTNHoller11 May 2025
WATCH: “There were ICE raids at the bars in downtown Nashville.” Singer Monte Mader says ICE agents were raiding bars on Broadway unlawfully — going after cooks, NOT criminals — and offers a plausible theory for why they wear masks. Full: instagram.com/reel/DJgZk_WO2…
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Simon Vandekar retweeted
nature
@Nature28 Nov 2024
Nature research paper: Study design features increase replicability in brain-wide association studies go.nature.com/4iaWEq5
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Thrilled to have worked with @meharpist and the amazing editorial team at @Nature on our paper! Honored to share our research!
Mary Elizabeth@meharpist9 Dec 2024
How can we increase the replicability of brain-wide association studies in a rigorous way? A @Nature paper by @kaidikangkk @jakob_seidlitz @rai_bethlehem @sattertt @VandyAtVandy et al identifies the relevant study design features that contribute nature.com/articles/s41586-0…

Study design features increase replicability in brain-wide association studies

Nature - Optimizing study design is critical for increasing standardized effect sizes and replicability, and the features that increase replicability in cross-sectional and longitudinal brain-wide...

nature.com
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Simon Vandekar retweeted
xinmengZ@ZXinmeng9 Dec 2024
New research alert 📣 Excited to share our latest study on the association between patient portal engagement and weight loss after #BariatricSurgery. jmir.org/2024/1/e56573. @ohpenlab @vumcdbmi @VUMCSurgery 1/3

Association Between Patient Portal Engagement and Weight Loss Outcomes in Patients After Bariatric...

Background: Bariatric surgery is an effective intervention for obesity, but comprehensive postoperative self-management is essential for optimal outcomes. While patient portals are generally seen as...

jmir.org
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It was such a pleasure to be a part of this work!
Mary Elizabeth@meharpist10 Dec 2024
Replying to @meharpist
And for those interested in the original @nature paper, it's here: nature.com/articles/s41586-0…

Study design features increase replicability in brain-wide association studies

Nature - Optimizing study design is critical for increasing standardized effect sizes and replicability, and the features that increase replicability in cross-sectional and longitudinal brain-wide...

nature.com
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Great job @RubyJXiong on this paper introducing GammaGateR, a semiautomated approach for marker gating in mIF data doi.org/10.1093/bioinformati…. With @KenLauLab @etmckinley @K_Harsim @cody_heiser et al. Tutorial is available online statimagcoll.github.io/Gamma….
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Kristin Poole O’Grady, PhD (@ogrady_kp), assistant professor of @VUMCradiology, has received research support totaling more than $2.4 million for her investigations of progressive #multiplesclerosis (MS) using advanced imaging. spr.ly/6018eiZ36

Kristin O’Grady receives $2.4 million for multiple sclerosis imaging studies

The awards will support O’Grady’s application of structural and functional magnetic resonance imaging to better understand symptoms and track MS progression in the lower spinal cord.

news.vumc.org
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🎤 It's my greatest honor to have such a fantastic lineup of speakers: Dr. Joshua Lukemire (@JoshuaLukemire) Dr. Mikail Rubinov Dr. Bennett Landman (@MASI_Lab) Don't miss our talks if you are interested. See you there!! #ICSAnashville @ICSA_Statistics @vandy_biostat
Kaidi Kang @kaidikang.bsky.social@kaidikangkk17 Jun 2024
🚀 Excited to organize this #ICSA2024 Invited Session #55 on neuroscience research. The topic will be "Reliable and Rigorous Inference for Brain Structure and Networks"! Join us on Tuesday, June 18th, 3:00-4:30PM. @VandyAtVandy @vandy_biostat
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One of the most common questions I get when talking about why you need to include the outcome in your imputation model is whether this is “double dipping” or “data leakage” — if this is you, what would convince you that this is not a concern?
Lucy D’Agostino McGowan@LucyStats18 Apr 2024
Curious why statisticians recommend including the outcome in your imputation models? Check out our new paper in Statistical Methods in Medical Research! @SarahLotspeich, @StatStaci5, and I show with some simple mathematical derivations why this is really a requirement!
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🌟Our paper linking the "exposome" with personalized functional brain network organization and cognition is now out in Developmental Cognitive Neuroscience! 🌟 sciencedirect.com/science/ar… findings summarized in the thread below 👇
Arielle Keller@ArielleKeller28 Aug 2023
New preprint! Our brains don’t develop in a vacuum, but enmeshed in a complex web of experiences+environments. How can we characterize the interconnected and co-occurring features of a child’s environment to better understand cognitive neurodevelopment? biorxiv.org/content/10.1101/… /1

A general exposome factor explains individual differences in functional brain network topography...

Our minds and brains are highly unique. Despite the long-recognized importance of the environment in shaping individual differences in cognitive neurodevelopment, only with the combination of deep...

biorxiv.org
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Using models generated from the Human Connectome Project Lifespan datasets, Dr. Anna Huang & @VandyAtVandy @WoodwardLab @StephanHeckers and @kaidikangkk explore thalamic abnormalities implicated in schizophrenia & other neurodevelopmental disorders nature.com/articles/s41386-0…
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Check out our latest collaboration with @Penn_SIVE and @VandyAtVandy improving statistical methods for widefield optical imaging, published in Journal of Neuroscience Methods. authors.elsevier.com/a/1iaBb…
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Presenting µBrain: a 3D atlas of @AllenInstitute histological slices of the developing brain, and tools for aligning gene expression/brain imaging! A beautiful labor of love led by @garedaba @DevelopingHCP @StuartJOldham @Aaron_A_B @emrobSci & others! biorxiv.org/content/10.1101/…

Molecular signatures of cortical expansion in the human fetal brain

The third trimester of human gestation is characterised by rapid increases in brain volume and cortical surface area. A growing catalogue of cells in the prenatal brain has revealed remarkable...

biorxiv.org
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We have a new preprint. In short: separate FDR for positive/negative effects avoids direction errors with 2-tailed tests. More power with adaptive BKY (vs BH). But visualization software needs asymmetric thresholds. w/@afni_pt, @ten_photos & Chris Rorden arxiv.org/pdf/2401.03554.pdf
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Mark your calendars for "Challenges in Neuroimaging Data Analysis” at @IMSI_Institute August 26-30, 2024 in Chicago. A fantastic line up of statisticians and neuroimaging experts will make for a stimulating week: imsi.institute/activities/ch…

Challenges in Neuroimaging Data Analysis • IMSI

imsi.institute
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Come to Neuroimaging Statistics at @OHBM, June 20-21! The Keith Worsley lecture will be given by Michael I. Miller, keynote lecture by Paul M. Thompson, and many other talks from the interface of statistics and neuroimaging. Registration free but required sites.google.com/view/neuroi…

Satellite Meeting of 2024 OHBM

sites.google.com
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Excited to announce the Notice of Award for my K23, "Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia" It truly takes a village, and I have the very best, with a mentorship team of @StephanHeckers @roscoebradyjr @cately00 @hilary_tindle @EdenEvins
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Simon Vandekar retweeted
Ken Lau Lab@KenLauLab8 Dec 2023
Excited to share our latest work in @CellCellPress on a spatial multi-omic atlas of human colorectal precancer-to-cancer transitions #CancerResearch. Huge congrats to @cody_heiser, Lau Lab grad student, for leading the charge as the first author! (1/8) cell.com/cell/fulltext/S0092…

Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal...

A spatial multi-omic atlas uncovers the diverse genetic and transcriptomic landscape of human colorectal lesions along progression to malignancy, highlighting the relationship between CRC evolution...

cell.com
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Simon Vandekar retweeted
Ted Satterthwaite@sattertt30 Nov 2023
Please RT! We are recruiting for two positions! Both are for recent grads, with a start date of Spring/Summer 2024. Great for people who want to do brain science, work in a fun envi, and prep for grad school (psych, neuro, etc). Info here: pennlinc.io/JoinUs

Jobs (All) | Penn LINC

pennlinc.io
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“Importantly, false positives were most common for small training datasets and large external datasets.” Starting to think more about power and machine learning in neuroimaging in this excellent work led by @RosenblattMatt !
Matt Rosenblatt@RosenblattMatt1 Nov 2023
Interested in external validation in neuroimaging? Check out our new preprint “Power and reproducibility in the external validation of brain-phenotype predictions” ⬇️ biorxiv.org/content/10.1101/…

Power and reproducibility in the external validation of brain-phenotype predictions

Identifying reproducible and generalizable brain-phenotype associations is a central goal of neuroimaging. Consistent with this goal, prediction frameworks evaluate brain-phenotype models in unseen...

biorxiv.org
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