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Thrilled to finally share our review where we dive into the mechanisms regulating the length of primary cilia in neurons and how this phenomenon might influence cellular signalling!
You can access the full article here: authors.elsevier.com/sd/arti…
@FlorianMerkle
Regulation of the length of neuronal primary cilia and its potential effects on signalling dlvr.it/SqYj7v
Viviana Macarelli retweeted
I'm excited to share our latest pre-print on proximity proteomics of primary cilia in human hypothalamic neurons, led by @VMacarelli, which revealed proteins involved in synapses and neurotransmission and the obesity-associated GPCR LPAR1. Details at bit.ly/4jcTodq
Happy to share our Science & Society article just published in @TrendsCellBio! We reflected on the value of joint peer review between early career researchers and mentors and you can read it here:
sciencedirect.com/science/ar…
Excited to finally read this!
Proud to share our work by a fantastic team, spear-headed by PhD student @Kainerox with major contributions by #xenopus expert @RosiFeistel.
We developed an improved iAPEX-based #ProximityLabeling method for #massspec based subcellular #proteomics.
biorxiv.org/content/10.1101/…
Thank you so much @TanosBarbara and @MennellaLab for being the examiners at my PhD defense! It was great to have the chance to discuss my PhD project with you!
Congratulations Viviana! @VMacarelli @FlorianMerkle @Cambridge_Uni
Great excuse to get together with some cilia peeps. We are missing a picture here… hopefully we can do that soon!
Even if attending online, I had a great time listening to all the amazing talks! And thanks to the organisers for printing and putting up my poster anyway! Looking forward to the next meeting!
@EuroCilia2024
Amazing tool!
Our paper "CilioGenics: an integrated method and database for predicting novel ciliary genes" is out in @NAR_Open !
academic.oup.com/nar/advance…
A preprint of this work was posted in April 2023.
1. We reviewed the literature for motifs described as sufficient for proteins localisation to primary cilia
2. We used these sequences to generate cytoplasmic and membrane-localised reporter constructs and tested their ability to target primary cilia of hIPSC-derived neurons
Viviana Macarelli retweeted
Please read, send feedback and retweet link to free full-text work on how a variant cell cycle coordinates differentiation of multi ciliated cells: rdcu.be/dJmnv
ALT Multiciliated cell
Had an amazing time at #FASEBCilia2024 and had the chance to meet amazing people!! – at St Paul, MN
Viviana Macarelli retweeted
New research led by Carolyn Ott, a senior scientist @JLS_Lab, provides the most detailed & comprehensive description yet of cilia in the mouse visual cortex, giving scientists new insights into the formation & function of this small & elusive organelle.
🔗doi.org/10.1016/j.cub.2024.0…
Viviana Macarelli retweeted
Excited to share that my PhD project has been published in @FrontCellDevBio! Introducing the ZebraReg platform. Hoping our work at @ZeClinics & @nmercaderh lab paves the way for new therapies to combat heart attacks in humans. 🐟 ❤️@scils_eu @ZebrafishRock frontiersin.org/articles/10.…
Viviana Macarelli retweeted
1.our latest preprint on ciliary TAK1 signaling in heart development and syndromic CHD co-led by the Larsen (@LarsAllanLarsen) and Christensen (@s_tvorup) labs. biorxiv.org/content/10.1101/…
Thrilled to share our recent preprint where we explore ciliary targeting sequences in hIPSC-derived neurons @FlorianMerkle @EdwardCHarding biorxiv.org/content/10.1101/…
Viviana Macarelli retweeted
🤞🤞🤞Best of luck to PhD student @VMacarelli from @IMS_MRL who is taking part in #STEMforBritain today! #stem4brit presenting her poster on 'THE ROLE OF PRIMARY CILIA IN METABOLIC SENSING IN HYPOTHALAMIC NEURONS'
STEM for BRITAIN 2024 is in @UKParliament on Monday 4th March! Congratulations to all our finalists listed at stemforbritain.org.uk/. Who will win one of our shiny medals🎖️? #stem4brit @RoyalSocBio @RAEngNews @RoySocChem @IMAmaths @PhysicsNews @physoc @NutritionSoc @UKRI_News
Had an amazing time at the #UKCilia2023 meeting, talking about #primarycilia and connecting with many new fantastic people!
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Can't wait to be there!
This looks like a fantastic meeting, where @VMacarelli, a talented PhD student from my team, will be presenting our disovery of a compact sequence that targets proteins to primary cilia in all ciliated cell lines we've tested so far, including human neurons. RT and apply!
Proud to be part of the @Cambridge_Fest with my photo realized as part of Cambridge Creative Encounters!
A busy time coming up for @IMS_MRL researchers #Camfest events this month. An #EscapeRoom: Research Breakthrough; a #CreativeEncounters project and an Art meets Science project @Cambridge_Fest. Find out more and join us if you can
👇👇👇👇
mrl.ims.cam.ac.uk/blog/ims-m…
ALT Cambridge Festival 2023: Art for Change through Engagement-Danielle Jones, IMS-MRL (NB not the final artwork)
ALT Cambridge Festival 2023: Creative Encounters project-Viviana Macarelli, IMS-MRL
ALT Cambridge Festival 2023: Escape Room: Research Breakthrough-IMS-MRL
Viviana Macarelli retweeted
Really excited for our event today on Drug Discovery, Computation and Dementia @ClareCollege with
@ChenCortina @FlorianMerkle and many others
All thanks to @CambridgeC2D3
