@ReiterLab

How are #cilia built, how do they signal, how do they go awry to cause ciliopathies, and how do we fix them?

 San Francisco, CA
reitergroup.ucsf.edu
Joined April 2011
  • Tweets1.4K
  • Following1.3K
  • Followers2.1K
150Media
Please read and critique our new paper on the genetic determinants of human kidney function @NatureGenet: rdcu.be/dTwye We combined GWAS with CNN and CRISPRi to go from loci to target genes. This roadmap may be useful to others uncovering genes underlying human traits.
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Sigh. @united’s first plane had a fuel leak. The second plane had a different undisclosed mechanical problem. The third plane has a broken reverse thruster. Does United not have any working planes?
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Only two more weeks to submit abstracts for the FASEB Cilia and Centrosomes. Abstract submission deadline is June 8. Submit an abstract and come share your exciting science with the community! events.faseb.org/event/cilia…
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Please come join me in Washington, DC August 2-6th for the FASEB SRC on Cilia and Centrosomes meeting! Over 40 talks will be selected from abstracts. We are also excited to launch our first North American Ciliopathy Summit, held at the same venue on Aug 2. events.faseb.org/event/cilia…
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Save the Date! The 14th Structural Birth Defects Meeting will be held September 21-23 @ChildrensPhila Keynote Speakers: Erica E. Davis at @LurieChildrens @NUFeinbergMed & Jeremy Reiter @ReiterLab @UCSF. Abstracts & registration open May 1. #14thSBD #structuralbirthdefects
14th Structural Birth Defects Meeting flyer Children's Hospital of Philadelphia; Philadelphia | September 21-23 2026; Abstract Deadline June 22; Photo of Children's Hospital of Philadelphia; Abstracts & Registration Open May 1; Keynote Speakers: Erica E. Davis, PhD, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University; Jeremy Reiter, MD, PhD, University of California, San Francisco

ALT 14th Structural Birth Defects Meeting flyer Children's Hospital of Philadelphia; Philadelphia | September 21-23 2026; Abstract Deadline June 22; Photo of Children's Hospital of Philadelphia; Abstracts & Registration Open May 1; Keynote Speakers: Erica E. Davis, PhD, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University; Jeremy Reiter, MD, PhD, University of California, San Francisco

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This is a wonderful collaborator with @ReiterLab @genophoria, Lu lab, and Flamant lab with supports from @UCSF @UCSFAging @UCSFstemcell. #PediatricCancer #Evolution @EvoDevoPanAm @SocDevBio
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Our new paper led by @XiaoxinChen2024 is out @PNASNews! bit.ly/4785aCD We built a tissue atlas of ~2K transcription regulators ➔ identified Tox3 as a long-sought Atoh1 amplifer in cerebellar development, tumorigenesis & evolution. 1/10 📢 We're recruiting postdocs!
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Reiter Lab retweeted
Daniel Kopinke@KopinkeLab
Mar 10
Thrilled to share our new study in collaboration with @TerenceRyan_PhD. We find that intramuscular adipose tissue (IMAT) directly impairs limb muscle function in PAD/CLTI and that preventing IMAT formation improves functional outcomes in experimental PAD. tinyurl.com/3efwaerh
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Check out this article in @ScienceMagazine featuring our Vilcek Prizewinners: Karolin Luger, @TakashiAkeraLab, @AashishManglik, and @BernaSozen_ !👏 These immigrant scientists are shaping the future of medicine, from uncovering the hidden mechanisms of our cells to advancing treatments for disease. 🔬✨ Read more about their discoveries: vilcek.co/3OxUKFG

Honoring immigrants in research: The Vilcek Prizes in Biomedical Science

Diverse voices overcome scientific challenges

science.org
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Reiter Lab retweeted
Gabriel Loeb@LoebLab
Feb 10
Polycystic kidney disease is the most common monogenic cause of kidney failure and affects over 10 million individuals. We've known most PKD is caused by mutations in PKD1 for over 30 years. But how PKD1 prevents disease has remained mysterious, limiting effective therapy.
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Reiter Lab retweeted
Alice Ting
@aliceyting
Jan 17
Janelia is hiring Group Leaders! Work alongside superstars like Luke Lavis, @JiefuBiol, @mengwang939, @JLS_Lab, @ERSchreiter. If you have ideas that are perhaps too ambitious or crazy for a traditional academic setting, that is exactly who they are looking for. Tool-builders at all career stages with original, transformative ideas for experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, and methods that don’t yet exist: Apply by Feb. 3, 2026: janelia.org/groupleader
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Excited to have my first senior author publication out in the world! An awesome collab between myself in the @ReiterLab and the Berbari lab at IU. We found primary cilia are necessary for postnatal pituitary development. 1/n. sciencedirect.com/science/ar…
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Save the date! PKDCON returns in 2026. Join us June 12–13 in the Chicago metro area, either in person or virtually. We can’t wait to see you there!
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Check out the latest work from our lab, done in collaboration with @FriedmanJed . Work was led by @sarah_jane210. @OuhscN
Kurt zimmerman@Zimmermk1986
1 Dec 2025
Frontiers | Maternal Western-Style Diet alters Kupffer Cell proportion leading to Metabolic Dysfunction-Associated Steatotic Liver Disease when challenged with western diet in adulthood frontiersin.org/journals/imm…

Frontiers | Maternal western-style diet alters Kupffer cell proportion leading to metabolic...

Exposure to maternal western-style diet (mWD) is associated with early development of metabolic dysfunction-associated fatty liver disease (MAFLD) in offspri...

frontiersin.org
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Alex Yashchecko, the first Ph.D. Student in lab, is defending his thesis today!
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In their Cell Science at a Glance article, Dagmar Wachten & Søren Tvorup Christensen @t_soren explore the primary cilium as a master regulator of cellular communication that integrates diverse signalling pathways in development & homeostasis. #JCSciliaSI journals.biologists.com/jcs/…
JCS poster - Primary cilia signalling at a glance

ALT JCS poster - Primary cilia signalling at a glance

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Good morning, Bay! I’m up early to head out to University of Florida @uflorida and Daniel Kopinke ⁦@KopinkeLab⁩. I hope to see you at the Dept of Pharmacology seminar Wednesday!
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I am excited to share our preprint of CiliaTrack, a novel machine learning approach to PCD diagnosis. Proud of Nicolas Hadas, a talented PhD candidate in my lab, for developing the code and his amazing work on this project. biorxiv.org/content/10.1101/…

Machine Learning Analysis of Cilia-Driven Particle Transport Distinguishes Primary Ciliary Dyskin...

Rational Primary ciliary dyskinesia (PCD) is a genetic condition that results in dysmotile cilia and abnormal mucociliary clearance. Despite advances in understanding the pathogenesis of PCD,...

biorxiv.org
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Check out our latest manuscript where we generate a cross model single cell and spatial atlas of mouse PKD! A cross model spatial and single-cell atlas reveals the conserved involvement of osteopontin in polycystic kidney disease | bioRxiv biorxiv.org/content/10.1101/…

A cross model spatial and single-cell atlas reveals the conserved involvement of osteopontin in...

Polycystic kidney disease (PKD) arises from mutations in cilia-associated genes, such as PKD1 and PKD2 , expressed in renal epithelial cells, leading to progressive kidney dysfunction and end- stage...

biorxiv.org
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More than 12 million people globally are impacted by ADPKD, and it still lacks disease-modifying therapies. Renasant Bio is on a mission to advance next-generation treatments for ADPKD through the development of small molecule correctors and potentiators. renasantbio.com/news-071025
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Thank you to all PKD community members who have advocated over the years, and all who are standing up for the PKD community during this important time. Together, we can #EndPKD. Want to add your voice? Join our Advocacy Champions Network: bit.ly/4l4nl0S
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