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Very happy to share a bit more of the PhD/Post-Doc work from my time @IDO_Helmholtz
In case you happen to be interested in the neuropeptide oxytocin and gut-brain signaling feel free to check out our latest preprint biorxiv.org/content/10.1101/…
Great work - pls check it out! :)
Looking forward to be exposed to more such novel concepts and innovative approaches
@PospisilikJ lab @VAInstitute
Two’s Two’s Two’s - Excited to share our study finding evidence of 2 major subtypes of obesity. Hope these can eventually help support more accurate understanding, diagnosis & treatment of #obesity and #diabetes. go.nature.com/3eNJF1s
Tim Gruber retweeted
A team of scientists led by VAI’s @PospisilikJ has identified two distinct types of obesity—findings that offer a more nuanced understanding of obesity than current definitions and may one day inform more precise diagnosis and treatment of disease: vai.org/obesity-subtypes
We’re honored that our work made it into this selection @Cell_Metabolism!
We are delighted that our work captured the enthusiasm of the readers of @Cell_Metabolism as one of the past year’s most exciting paper in metabolic research 🙏🏼 @TimGruber14 @IDO_Helmholtz @DiabResearch @ERC_Research @SyNergy_Cluster @LMU_Uniklinikum #astrocyte #hypertension
I am very grateful that I could keep enjoying to work on my favorite neuropeptide, a passion that was kindled in the lab of Valery Grinevich during my masters.
Thanks to these three mentors of mine!
Big ‘thank you’ to everyone involved - Wouldn’t have been possible without you!!
Special thanks to @CGarciaCaceres and @MatthiasTschop for continual support and encouragement with this (admittedly non-astrocyte ☺️) project.
Tim Gruber retweeted
Finally out 🥳🥳🥳 Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner onlinelibrary.wiley.com/doi/… – at Manises, Spain
Tim Gruber retweeted
.@TimGruber14 finds that obesity induced remodeling of the gliovascular interface within the hypothalamus leads to arterial hypertension. @Cell_Metabolism @CGarciaCaceres @MatthiasTschop @helmholtz_diabc @HelmholtzMunich #JRNLclub jrnlclub.org/research-films/…
Delighted and honored to have written a comment with @CGarciaCaceres featuring the great work recently published by D. Ameroso @dommistar, @Rioslaboratory and colleagues in @NatMetabolism
nature.com/articles/s42255-0…
Tim Gruber retweeted
We are thrilled to share that the first research paper from our lab describing coordinated remodeling of the epigenetic landscape in the mouse cortex is now published @NatureNeuro. Check it out at nature.com/articles/s41593-0… with a short summary of the key changes in revision below:
Starting 2022 with the imo most fascinating neuropeptide <3
More intricacies of the OT system soon to be revealed - stay tuned ;)
Oxytocin has some of the broadest signalling roles in the body, but how do neurons know when and where to release it for each application?
Charles Fraser explains how neurons coordinate the release of oxytocin.
More in the latest 🎧 #eLifePodcast
elifesciences.org/podcast/ep…
ALT Oxytocin-synthesizing neurons in the hypothalamus fluorescing in a rainbow of colours
Tim Gruber retweeted
Impact of Weight Loss on Brain Age: Improved Brain Health Following Bariatric Surgery
@YasharZeighami @DadarMahsa @alain_dagher
arxiv.org/abs/2112.06140
Tim Gruber retweeted
Our research group is now on Twitter! Follow for @GRSC_UQTR for exciting research news :-)
Tim Gruber retweeted
The brains of #COVID-19 patients have damaged blood vessels (more so-called string vessels representing remnants of lost capillaries); SARS-CoV-2 infects brain endothelial cells and leads to microvascular pathology via RIPK signaling
go.nature.com/2ZavprG
Tim Gruber retweeted
After a summer break we are back to the Epigenetics&Metabolism Webinar series! Join us to hear about the epigenetic regulation of metabolic diseases by Prof. J.Andrew Pospisilik @PospisilikJ on September 16th. Organized by @Indraiitr and @CSebastianLab.
Tim Gruber retweeted
I enjoyed my podcast interview with @ihmc_stemtalk where we covered several topics including body weight biology, exercise science and emerging anti-obesity drugs ihmc.us/stemtalk/episode-126…
Tim Gruber retweeted
"You are as old as your blood vessels"
Vascular growth factors control healthy ageing and lifespan:
"Counteracting age-related VEGF signaling insufficiency promotes healthy ageing and extends life span" science.sciencemag.org/conte…
Tim Gruber retweeted
RegPep2020 Special Issue of articles on the role of regulatory peptides in systems physiology ‐ now out @JNE_Editor. Check it out at onlinelibrary.wiley.com/toc/… . Thanks to Guest Editors from IRPS for their hard work. RegPep23 coming up next month - regpep.org/keynote-speakers-…