A group of chemical biologists at Imperial College London and the Francis Crick Institute
London
Joined May 2012
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- Following156
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Ed Tate retweeted
Congratulations to Myricx Bio, a spinout co-founded by @TateScience based on research from @impchemistry & @TheCrick, which has raised £90m to move its novel cancer treatment into clinical development 👏 @RoySocChem #startup #cancer @imperialcollege
imperial.ac.uk/news/254635/i…
Ed Tate retweeted
Funded by @ERC_Research, a new study from the lab out in @NatureComms discovers how a tiny protein called CD59 provides a last line of defence against a giant b-barrel immune pore. rdcu.be/c5L1L. @EmmaCouves @TomasVoisin @scott_d_gardner @TateScience @pstansfeld
ALT CD59 (pink) captures and redirects pore-forming b-hairpins of MAC assembly intermediates (blue).
Ed Tate retweeted
Computational resources provided by @hecbiosim allowed us to see how the lipid environment could tip the balance between CD59 as an immune regulator or host receptor hijacked by bacterial virulence factors.
Excited to share new work from the lab explaining how human cells are protected from MAC pores during an immune response. Big thanks to @ERC_Research and @eBIC_Diamond for making this work possible! In collaboration with @TateScience and @pstansfeld biorxiv.org/content/10.1101/…
Ed Tate retweeted
@TateScience is the best environment to do great science with amazing scientists of any gender - so lucky to be here!
#INTERNATIONALDAYOFWOMENINSCIENCE imperial.ac.uk/news/233875/i…
Ed Tate retweeted
📢The ICB CDT has released 6 NEW STUDENTSHIPS!📢
Come and be a part of our team!
More info, including how to apply, in the link below ⬇️
imperial.ac.uk/chemical-biol…
Ed Tate retweeted
To identify the proteases responsible for specific proteolytic events in complex milieux, @TomaKryza @scottlovell34 @TashbibK @TateScience @ProfJohnHooper developed a substrate-biased activity-based probe approach. Free to read: rdcu.be/ciLkO. nature.com/articles/s41589-0…
Ed Tate retweeted
Our epic @TateScience preprint goes live!
We discover that N-myristoyltransferase inhibition selectively kills MYC-deregulated cancer cells via a mitochondrial failure mechanism:
biorxiv.org/content/10.1101/…
Honoured to be joint-first with fantastic @lueg_g and @MonicaFaronato!
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Ed Tate retweeted
New Research Associate in Chemical Biology position in our group in collaboration with @bugsinblood targeting antimicrobial resistance. For more information, or to apply, see: imperial.ac.uk/jobs/descript…
Ed Tate retweeted
We are seeking a Research Associate in Chemical Biology to lead research targeting deubiquitinases, in close collaboration with scientists @pfizer imperial.ac.uk/jobs/descript…
Ed Tate retweeted
Check out this great animation by @impchemistry PhD student @cassandrak94 where she explains her research into understanding immune responses using chemical biology: imperialcollegelondon.app.bo… ! Hear her talk about her research at the FoNS Research Showcase! imperial.ac.uk/events/119877…
Very happy to have been nominated by @impchemistry to take part in the @ImperialSci research showcase! Check out my video about my work: imperialcollegelondon.app.bo…
Ed Tate retweeted
Check out the group's first paper (@NottsChemistry @angew_chem) now online and open access! Great work from Rhys, Fran, and the rest of the team. A new method for the site-selective modification of peptides and proteins. More to come from this method soon.
onlinelibrary.wiley.com/doi/…
Ed Tate retweeted
Come join our team @imperialcollege! We are recruiting a @ERC_Research funded postdoc position using #cryoem to understand how the complement system is controlled.
imperial.ac.uk/jobs/descript…
Ed Tate retweeted
Thanks to @h_dunning for writing this piece on our work for @imperialcollege news!
imperial.ac.uk/news/200174/f…
Ed Tate retweeted
It's finally here in glorious typeset form. We've found this tool useful, and hopefully you will too. Many thanks to all the coauthors, and the funders for supporting us to do the work #ProteomeEngineering @imperialcollege @wellcometrust @royalsociety @BBSRC @TateScience
CRISPR-TAPE, a new #CRISPR gRNA design tool for targeted protein engineering: protein-centric gRNA identification & selection by targeting nucleases to specific amino acid residues/types --> bit.ly/2XWh3ab
@laboratorychild @imperialcollege #GenomeEngineering
Ed Tate retweeted
Honoured to take part in the President @Alicegast ‘s address and be named in the booklet together with some superstars in @impchemistry including @YuvalElani @DiMicheleLAB1 @JelfsChem @bakulingroup @FuchterMatt @TateScience – at Camden Town, London
Ed Tate retweeted
Exciting opportunity for a passionate chemical biologist to join the Crick-GSK LinkLabs. 3-year postdoc position working on a project joint with my lab @TheCrick. Exploring the development and use of cyclic peptides in cells. jobs.gsk.com/en-gb/jobs/2394… #chemjobs #chembio #DELs
Ed Tate retweeted
Delighted this paper on IFITM3, with twist of bats, is finally published. Huge thanks to all co-authors including @MarkCPMarsh @PaulKellam_2 @edwardcholmes @TateScience @MRC_LMCB
A new comparative immunology study by Benfield et al. examines the evolution and function of bat antiviral IFITM proteins, helping us to understand how bats host, and seemingly tolerate, numerous zoonotic viruses. @CamillaBenfield @RoyalVetCollege bit.ly/36lb8hA
Ed Tate retweeted
Really proud of our new paper reversing #AMR -congrats to all involved! Plus so surreal to see my name as last author for the first time...! Thank you @TateScience & @bugsinblood sciencedirect.com/science/ar…
Ed Tate retweeted
Very happy to see our Acyl-cLIP lipidation assay paper online @ChemicalScience and perfect timing to present at the @FASEBorg #lipidation meeting tomorrow! @TateScience pubs.rsc.org/en/content/arti…
