@MarkCPMarsh

MRC LMCB at UCL

Joined July 2009
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  • Followers116
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Save the date! We're excited to announce the new UCL BIIG (BioImage Interest Group, launching on October 13! Join the new mailing list and keep up to date with the groups’ activities here: ucl.ac.uk/lmcb/ucl-biig
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A new publication in @PLoSPathogens by the Marsh Lab and colleagues at @PennMedicine explores the role and relevance of the conserved tyrosine-dependent motif in the HIV and SIV envelope protein cytoplasmic domain. journals.plos.org/plospathog…

A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected...

Author summary In the cytoplasmic domain (CD) of their envelope glycoproteins (Env), all human and simian immunodeficiency viruses (HIV and SIV) have a tyrosine-dependent motif that is a potent...

journals.plos.org
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Our paper with Jim Hoxie, Nick Maness and many other great collaborators is now on BioRxiv - A tyrosine-based trafficking signal in the simian immunodeficiency virus envelope cytoplasmic domain is strongly… disq.us/t/3vx4vov
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Our paper with Jim Hoxie, Nick Maness and many other great collaborators is now on BioRxiv - A tyrosine-based trafficking signal in the simian immunodeficiency virus envelope cytoplasmic domain is strongly… disq.us/t/3vx4vov
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Influenza virus imaging review is now out! mdpi.com/1999-4915/13/2/233 "Application of Super-Resolution and Advanced Quantitative Microscopy to the Spatio-Temporal Analysis of Influenza Virus Replication" in @VirusesMDPI Thanks @EmmaTouizer @Chr_Sieben @MarkCPMarsh @HenriquesLab
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Replying to @Julie_YueYuan
@Julie_YueYuan and @caron_ajacobs paper is out! Single-Molecule #SuperResolution Imaging of #TCell Plasma Membrane #CD4 Redistribution upon #HIV Binding. Collaboration with the @MarkCPMarsh laboratory, and our first paper with @IGCiencia co-affiliation =) mdpi.com/1999-4915/13/1/142
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Gods have chosen to give us critical but friendly reviewers. Paper accepted =)
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Great work from @EmmaTouizer on putting together this review of #influenza advanced imaging, from super-resolution microscopy to quantitative analysis and new labelling strategies! Thankful for the great collaboration with @HenriquesLab and @Chr_Sieben and @MarkCPMarsh on this.
Preprints.org@Preprints_org6 Jan 2021
Application of Super-Resolution and Advanced Quantitative Microscopy to the Spatio-Temporal Analysis of Influenza Virus Replication preprints.org/manuscript/202… #LifeSciPreprints #PreprintsOrg @EmmaTouizer @Chr_Sieben @HenriquesLab @LaineBioImaging
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First @biorxivpreprint of 2021! We used #SuperResolution imaging and physical #modelling to describe how #HIV-1 triggers CD4 reorganisation upon binding, its main host-cell receptor. An exciting collaboration with the Llorente Garcia and @MarkCPMarsh labs biorxiv.org/content/10.1101/…
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Stay tuned! Less than a week to go until applications open for our 4-year Molecular Cell Biology PhD Programme! @UCLLifeSciences @The_MRC #findaphd
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Great collaboration with Andrew Shevchuk and colleagues!
UCL Laboratory for Molecular Cell Biology@LMCB_UCL18 Aug 2020
New publication by Andrew Shevchuk and @MarkCPMarsh finds HIV virus-like particles assemble and release more than 10x faster than previously reported. @PNASNews @UCLLifeSciences @imperialcollege pnas.org/content/early/2020/…

Rapid formation of human immunodeficiency virus-like particles | PNAS

Understanding the molecular mechanisms involved in the assembly of viruses is essential for discerning how viruses transmit from cell to cell and h...

pnas.org
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A shout out to @HenriquesLab for their May 2020 Traffic Editors' Choice paper! onlinelibrary.wiley.com/doi/…
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We are delighted to announce that @Athena_SWAN has renewed our GOLD award in recognition of our ongoing commitment to advancing equality, diversity and inclusion. A special thank you to the entire EDI Committee and @UCLEqualities for support!
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This is #ChikungunyaVirus imaged by cryo-electron microscopy 🔬The level of detail we can now get blows me away 😱 Want to know why I love science? LOOK HOW AMAZING IT IS. You can very clearly see the E2 protein crossing the lipid bilayer 👨🏼‍🔬 Ref on sub tweet #virology #scicomm
Chikungunya virus Cryo-electron micrograph as images by Basore et al, 2019

ALT Chikungunya virus Cryo-electron micrograph as images by Basore et al, 2019

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For those of you who missed Monday's #LMCBseminar by @MarkCPMarsh and @StuartMWeston on enveloped viruses and SARS-Cov2. You can watch the entire seminar on our Vimeo channel vimeo.com/413543931
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Very please to see Sebastian's final paper from the lab appear at last #mdpiviruses The Nef Protein of the Macrophage Tropic HIV-1 Strain AD8 Counteracts Human BST-2/Tetherin @VirusesMDPI. Thanks to Scott for pulling it all together!
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Our paper - #SuperBeacons: Open-source probes with spontaneous tuneable blinking compatible with live-cell #SuperResolution #Microscopy - now peer-reviewed and published =). Check it out onlinelibrary.wiley.com/doi/…
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The Traffic Editors appreciate the difficulties in addressing reviewer requests for new experiments due to global restrictions. In this current climate, please be assured that we will endeavour to keep requests for new experiments to a minimum as we carefully assess of your work.
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Journals: Could you please make your articles open access while we are all working from home? @nature and others.
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Celebrating all the inspirational women undertaking careers in science at the @MRC_LMCB and across the world. #womeninscience @WomenScienceDay ⁩ #WomenInStem #IDWGS
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