@SpragginsLab

Student-run Twitter page for @JeffSpraggins | @VanderbiltCDB | @VU_BIOMIC

 Nashville, TN
medschool.vanderbilt.edu/biomic/
Joined July 2021
  • Tweets202
  • Following288
  • Followers415
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If you want to map Cells in situ, then come see #HuBMAP’s OMAPs here: nature.com/articles/s41592-0… Teal – proximal tubules Dark blue – vasculature Pink – podocytes in glomeruli Yellow – mesangial cells in glomeruli @SpragginsLab @VU_BIOMIC #WomenInScience

Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging

Nature Methods - Organ Mapping Antibody Panels are a community-led initiative to create standardized antibody panels for multiplexed spatial imaging.

nature.com
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Spraggins Lab retweeted
Ken Lau Lab@KenLauLab30 Oct 2024
Replying to @K_Harsim
@K_Harsim, @cody_heiser, @VandyAtVandy developed Multiplex Image Labelling with Regional Morphology (MILWRM) to identify consensus tissue domains in spatial transcriptomics (ST) and multiplex immunofluorescence data (mIF) @NCIHTAN nature.com/articles/s42003-0…

Consensus tissue domain detection in spatial omics data using multiplex image labeling with...

Communications Biology - MILWRM is a Python package that can perform tissue domain detection on spatial transcriptomics (ST) and multiplex immunofluorescence (mIF) data across multiple specimens.

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dark blue-nuclei, yellow-smooth muscle cells, red-leukocytes, magenta-Mueller glia, green-bipolar cells, light blue-cone cells, white-fibroblasts, and light pink-retinal pigmented epithelium @SpragginsLab @VU_BIOMIC #WomenInScience #HuBMAP
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Benedikt Geier@benebio3D12 Sep 2024
Excellent lightning talks from yesterday’s #SBS2024 by @youkimdoit from the Amieva lab, @Stanford and Cody and Thai from the @SpragginsLab at @VanderbiltU and many more!
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Spraggins Lab retweeted
Eric Skaar@EricSkaar31 Jul 2024
Imaging of gangliosides during Staph infections. New paper from ⁦Katerina Djambazova and the ⁦⁦⁦⁦@SpragginsLab⁩. Happy to be involved in this beautiful work⁩. ⁦@J_ASMS⁩ 🔬 🦠 pubs.acs.org/doi/10.1021/jas…

MALDI TIMS IMS Reveals Ganglioside Molecular Diversity within Murine S. aureus Kidney Tissue...

Abstract. Gangliosides play important roles in innate and adaptive immunity. The high degree of structural heterogeneity results in significant variability

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Eye hope we can see eye to eye - beauty is in the eye of the beholder & you will see r-eye-t away this CODEX image from #_hubmap researcher Dr. Angela Kruse @SpragginsLab @VanderbiltU is a vision to behold w/ its retinal retinue of proteins! Eye know you’ll like what you see!
Alt text: CODEX image of retina from human donor

ALT Alt text: CODEX image of retina from human donor

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Always a great time getting together with @SpragginsLab & @vandeplaslab for our annual SVP dinner! #ASMS2024 – at Anaheim, CA
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The Prentice lab is looking forward to #ASMS2024! Come check out our work on gas-phase ion/ion reactions, imaging, ion mobility, and more! @asmsnews
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Eye know what you're thinking. It's pretty nervy to show this CODEX image of a human optic nerve made by #_hubmap researcher Dr. Angela Kruse @spragginslab @vanderbiltU, but the optics of this image are eye-pealingly eye-deal!
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Eye see you over there, looking for the nerve to discover the workings of your inner eye! Let #_hubmap researcher Dr. David Anderson @vanderbilt show you the way with this MALDI #IMS image of the lipids in different tissue types w/in the optic nerve! #glaucoma awareness
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Kudos @JeffSpraggins on your promotion to associate professor and @KenLauLab on your promotion to professor! @VanderbiltCDB
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This #MALDI image of a ciliary process in a human eye from Dr. David Anderson @SpragginsLab , will put you in good aqueous humor! Of course, that line only works if you know that is where aqueous humor, the fluid in your eyes, is made, but eye have faith in the audience 📷
Human eye MALDI image

ALT Human eye MALDI image

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Out of the frying pan and into the pancreas! @angelakrusephd at @spragginslab used #3DMicroscopy to open a window pane within the pancreas showing a neural node. The pancreas makes enzymes necessary for the pandemonium of digestion, a real Pandora's box if ever there was one!
Neural node of pancreas

ALT Neural node of pancreas

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Excellent opportunity in the Gonçalves Lab at TU Delft. #MachineLearning #Bioinformatics #AI #genetics #transcriptomics #proteomics #spatialbiology #PhD #postdoc #Vacancy
Gonçalves Lab@GoncalvesLab26 May 2023
Hiring twice, join us at @tudelft! See thread for details/links. - Postdoc/PhD: multimodal ML for molecular maps of human tissue in health & disease (@_hubmap). - PhD: computational analysis of individual diversity in complex disease using cell "villages" of human donors (iCELL).
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So happy for Jackie! Her presentation at #ASMS2023 on our work with @EricSkaar and @vandeplaslab on how infection alters tissue microenvironments was simply stunning. Way to rep our lab and @VanderbiltChem @VanderbiltCDB
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So proud of the amazing work and wonderful presentation by Ally Esselman (grad student @VanderbiltChem) at #ASMS2023. Thanks to our collaborators and friends in the @vandeplaslab – at Houston, TX
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Great panel discussion at the #ASMS2023 imaging workshop panel tonight. Thanks to all of the presenters and attendees! @min_fan59925 @LabLaskin @BrodSquadUT @Tingting_Yan9 @EllisMSILab @KateDjambazova @SpragginsLab @PrenticeLabUF @IMSSNews
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Spraggins Lab retweeted
Eric Skaar@EricSkaar18 Apr 2023
Contour mapping of imaging mass spectrometry and microscopy data from Staphylococcus aureus infected kidneys. Awesome new approach from ⁦@KavyaSharman⁩, ⁦@SpragginsLab⁩, and ⁦@CaprioliLab⁩, published in ⁦@J_ASMS⁩ 🔬 🦠 pubs.acs.org/doi/10.1021/jas…

MALDI IMS-Derived Molecular Contour Maps: Augmenting Histology Whole-Slide Images

Abstract. Imaging mass spectrometry (IMS) provides untargeted, highly multiplexed maps of molecular distributions in tissue. Ion images are routinely prese

pubs.acs.org
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Like the look of this #MALDI #IMS image of a human optic nerve from @_hubmap researcher Dr. David Anderson at the @spragginslab? Eye think it’s downright nervy and visionary, and that’s no lie! #retina
MALDI IMS image of a human optic nerve

ALT MALDI IMS image of a human optic nerve

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🔬 more from @SpragginsLab "Tissue registration and exploration user interfaces in support of a human reference atlas." nature.com/articles/s42003-0… @VUBasicSciences

Tissue registration and exploration user interfaces in support of a human reference atlas

Communications Biology - The software tools and user interfaces for the registration and exploration of tissue data for the human reference atlas are presented, providing evaluation metrics for...

nature.com
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