Pathologist-scientist I McGill Melanoma Research | Postdoc position available (Search Best of Canada 2026)
Montréal, Québec
Joined May 2018
- Tweets1.7K
- Following892
- Followers1.9K
- Likes6K
Pinned Tweet
1/ 🚨 Excited to share our latest publication in Pathology! We explored the role of tumour necrosis as a prognostic factor in vulvar and vaginal melanomas (VVMs) and recommend that this be reported in synoptic surgical pathology templates to help refine staging.
Practical tips for starting a biomedical research lab! Group effort with Irving Cancer Immunology Symposium attendees, co-led with @amycfanphd. Thanks Nir for bringing us together.
Roy et al. posit that scientific independence alone is insufficient to build a sustainable lab under uncertain funding & offer practical guidance for defining a research vision, allocating resources, navigating funding opportunities & supporting trainees hubs.la/Q04zV5DW0
Simon Roy MD retweeted
Proud to share our new paper in Science Advances.
We show that indoor tanning causes widespread mutational damage across the skin to increase melanoma risk, especially in body sites that rarely see sunlight.
science.org/doi/10.1126/scia…
#Melanoma #SkinCancer #CancerResearch
Simon Roy MD retweeted
I am really happy to see the #preprint of our work studying #acral #melanoma tumours from 🇲🇽 Mexican patients out today! This has been a ~8 year-long work involving many colleagues from Mexico and abroad. Some of our findings here below.... ⬇️ (1/12)
Ancestry and somatic profile predict acral melanoma origin and prognosis medrxiv.org/cgi/content/shor… #medRxiv
Simon Roy MD retweeted
An honour to listen to Ruth Halaban @Yale, the first woman that graduated from @Princeton with a PhD degree in biology and recipient of the @PASPCR1 lifetime achievement award, talk about the #LZTR1 gene and #melanoma – at Manhattan, NY
WNT-activated melanocytoma with background melanocytic nevus. You don't always get such a good beta-catenin staining, got lucky over here. These often are concerning clinically due to the heterogenous pigmentation. #dermpath
ALT Wedge-shaped compound melanocytic lesion
ALT A central portion shows larger, pigmented melanocytes with dusty cytoplasm and a pigment grid/checkerboard pattern (Arnaud's trick) of melanophages
ALT Beta-catenin staining nuclei of that same area while not labelling the background nevus (lower left)
Simon Roy MD retweeted
FRESH OFF THE PRESS - New study in @escardio @ESC_Journals Prediction of incident atrial fibrillation using deep learning, clinical models and polygenic scores shows #AI can predict new-onset atrial fibrillation from ECGs with high accuracy, outperforming clinical and genetic risk scores. #ESC2024 #ESCCongress
academic.oup.com/eurheartj/a…
📌 Bookmark, reshare, and read this thread! We're taking you on a journey of our main findings BELOW #OpenScience 🧵👇
Simon Roy MD retweeted
68♂️ w/ lytic femur mass
Is it...
1️⃣ Sarcoma?
2️⃣ Melanoma?
3️⃣ Carcinoma?
4️⃣ Lymphoma?
🔎WSI: kikoxp.com/posts/46908
💡 Answer: kikoxp.com/posts/46910
#BSTpath (...or is it? 🤔)
Simon Roy MD retweeted
We study epigenetics in cancer immunology at #Yale and we are hiring: miceviclab.github.io/postdoc… #newPI
Chondrodermatitis nodularis helicis! You don't always see the "textbook" cartilage alterations. #dermpath
Simon Roy MD retweeted
.@MengWang55 @ShainLab @IweiYeh @Ishanibanik1 @UCSF @UCSFCancer sequence #AcralMelanoma at different stages, find punctuated clusters of copy number alterations and specific driver mutation timing
#CancerResearch @NatResCancer nature.com/articles/s41467-0…
Simon Roy MD retweeted
Awesome #tweetorial 4 #dermpath #gynepath & #PathTwitter - not surprising as #tumor necrosis --> aggressive growth across many tumor types. It was a honour to work with @SimonRoyMD and Vincent to bring attention to this gendered #melanoma that so far is not well studied!
5/ 📈Kaplan-Meier survival analyses confirmed that tumour necrosis predicts poor outcomes for disease-specific, progression-free, and metastasis-free survival (p<0.001).
📉 Vaginal melanomas showed worse survival outcomes compared to vulvar or clitoral melanomas.
We suggest that tumor necrosis should be included in the prognostic models for VVMs. Grateful to my co-authors and all Can instit. for making this research possible. #dermpath #melanoma #Pathology #CancerResearch Thanks @redsnapperpath and Vincent Trinh for steering the ship!