Neuroimmunologist | Anatomist | @bu_cte center| MD/PhD Candidate with Drs McKee & Huber

Boston University
Joined October 2019
If you’re heading to AAIC this weekend check out my talk and poster (#114) on Wednesday examining the role of CNS Tcells in human tauopathy @alzassociation
Replying to @bu_cte
Several of our BU CTE Center team members are presenting at the @alzassociation International Conference (AAIC) which begins Sunday in Philadelphia, PA. Swipe to learn more about their presentations and click here to learn more about AAIC: aaic.alz.org @SamCalderazzo @SydneyMosaheb (2/2)
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Samantha Calderazzo retweeted
Antigen-specific age-related memory CD8 T cells induce and track Alzheimer’s-like neurodegeneration | PNAS pnas.org/doi/10.1073/pnas.24…
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Happy to share our new research assessing the neuropathology behind Parkinsonism in CTE @bu_cte
Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual pathology related to CTE and football play and not the typical Lewy body pathology found in most cases of Parkinson disease. ja.ma/3y96Q06
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Samantha Calderazzo retweeted
Exciting news! In a new study, @bu_cte found a connection between a brain protein buildup (p-tau) and thinking/behavioral issues in #CTE, which could help diagnose the disease while people are alive. 🧵(1/2).
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Samantha Calderazzo retweeted
#GliaPapers REVIEW @GLIA_Journal Gal Ronit Frumer, @TheJungLab, Jung-Seok Kim, @WeizmannScience A review of recent advances in the understanding of brain macrophage heterogeneity. onlinelibrary.wiley.com/doi/…
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Congratulations to Katharine Babcock (@kjbabcock9), a PhD student in the McKee Lab, who successfully defended her dissertation yesterday! We are proud of all she has accomplished and look forward to continuing to work with her as a postdoc at BU CTE. Congrats, Dr. Babcock!
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CTE can affect young amateur athletes. @nytimes has highlighted the stories of a few families whose loved ones were part of our recent study and provide an interactive summary of the findings
They died young. Most played football. Only a few came close to the pros. But like hundreds of deceased NFL players they, too, had CTE, the brain disease linked to repeated hits to the head. If their families could go back, would they still let them play? nyti.ms/3QZohHb
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Samantha Calderazzo retweeted
_ @SamCalderazzo with her @bu_cte lab mate, @heloise_leblanc with the Ramirez group, and @been_snyder with the Medalla Lab #SfN2023
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Samantha Calderazzo retweeted
We'd like to thank @ConcussionLF for hosting our team at their 16th Annual Concussion Legacy Gala last night! It was a fun-filled night dedicated to such a great cause.
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First sfn in the books repping CNS immune cells @mo_but
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There is one week left to help the Circo family reach their $30,000 fundraising goal. If you'd like to support CTE research, you can donate here: bit.ly/supportbucte You can learn more about Mario here: bit.ly/bucte_mariocirco
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Replying to @ConcussionCTEfn
@ConcussionLF & @annmckeemd, Thank you for honoring my beautiful mother, the 1st public #DVCTE case, during #DomesticViolenceAwarenessMonth & creating awareness about the unrecognized #DVTBIPandemic impacting millions. Let's end it together. #DVTBIVictims
Replying to @ConcussionCTEfn
While this case is the first public CTE diagnosis linked to DV, millions worldwide suffer from similar brain trauma. Dr. María Garay-Serratos, founder of @PanfilaHOPE, wants her mother’s story to ignite a lifesaving global conversation during Domestic Violence Awareness Month.
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New study from my center reports CTE found in over 40% of young contact sport athletes including those who only played through highschool
NEW RESEARCH: Learn more about our new paper out today in @JAMANeuro on young contact sport athletes exposed to repetitive head impacts. First Author: Ann McKee, MD (@annmckeemd) Senior Author: Michael Alosco, PhD Read it here: bit.ly/bucte_youngathletes (1/3)
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🔈 Listen Now: Learn more about our new research from BU CTE Center director and first author @annmckeemd in the @JAMANeuro podcast below with @cynarmandmd
JAMA Neurology Web Editor @cynarmandmd and author @annmckeemd discuss "Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts." ja.ma/47SZ9Iq
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Samantha Calderazzo retweeted
For those just now realizing insurers don’t care if you live or die— 🚨🚨🚨Insurers do not care if you live or die. In fact, death is highly cost effective, especially if it is fast, and especially if you are chronically ill. Up to 25% of all Medicare expenditures are spent on the last 12 months of life. Insurers would love to eliminate that, as the cost of care >>> premiums collected at that point. Remember that what you call healthcare, they call LOSS — as in, their medical LOSS ratio being the how much $ of premiums is spent on medical care. And they would love to cut the loss, for our (unfortunately) most vulnerable populations — elderly, chronically ill, with little support.
Here’s the dirty secret of emergency medicine: We don’t have to do prior auth. Like ever. We just order what the patient needs, and the patient gets it done in the ED. But here’s why we care about prior auth anyways: B/c not a shift goes by where a patient doesn’t land in the ER as a last resort when #priorauth denied or delayed them the outpatient care they needed.
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Samantha Calderazzo retweeted
Here’s the dirty secret of emergency medicine: We don’t have to do prior auth. Like ever. We just order what the patient needs, and the patient gets it done in the ED. But here’s why we care about prior auth anyways: B/c not a shift goes by where a patient doesn’t land in the ER as a last resort when #priorauth denied or delayed them the outpatient care they needed.
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Dr Killiany was always willing to aid any of the students in the department. I will always cherish the advice and collaboration he provided during my time there
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Samantha Calderazzo retweeted
A simplified overview of brain function: #neuroscience
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Samantha Calderazzo retweeted
A growing body of evidence suggests that brain-resident CD8 T cells and IFNg drive cellular and cognitive #aging in the #brain. Our @NatImmunol commentary on recent advances from @NatureNeuro goes into the #neuroimmunology mechanisms rdcu.be/c2HQ1
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