
The West Lab @TheCrick studies mechanisms of DNA Recombination and Repair. Tweets by lab members, unless signed SCW. Views are own
London
Joined December 2022
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The West Lab retweeted
Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳
Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! rdcu.be/d1F7m
The West Lab retweeted
We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home…
The West Lab retweeted
📣#RECOMBINATION25 PROGRAMME NOW LIVE!
Exciting news! The first draft of the programme for the 2nd Recombination Mechanisms conference is now available. 🌟
🗓Important Deadlines:
Early Bird & Talk Submission – 28 Nov 2024
Poster Submission & Registration Deadline – 13 Mar 2025
Don’t miss out—check out the programme and get all the details here:
bit.ly/4ekGnMz
The West Lab retweeted
Delighted to share that my manuscript of "Mechanism of single-stranded DNA annealing by RAD52-RPA complex" is now in Nature!
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s41586-0…. Thread ⬇️⬇️⬇️ (1/8)
The West Lab retweeted
Congratulations to Caroline Hill and Xiaodong Zhang on being awarded almost £6 million in @wellcometrust Wellcome Discovery Awards to study DNA repair and organ development in zebrafish and humans 🥳
crick.ac.uk/news-and-reports…
The West Lab retweeted
We awarded our annual Translation Prize last night, recognising researchers at the Crick who are applying their research in a real-world setting.
Congratulations to our winner Anaid Benitez, runner-up Andreia Bernardo and all the nominees! 🏆🎉crick.ac.uk/news/2023-10-13_…
The West Lab retweeted
A recent publication on Nature showed new DNA repair mechanism uncovered by the @Francis Crick Institute with C-Trap, proving RAD51 paralogs as crucial as the BRCA2 pathway in cancer prevention. Learn more about it: bit.ly/3DukiLq
The West Lab retweeted
The #Recombination23 Poster Session is in full swing and what wonderful weather we have for it… 🧬☀️
The West Lab retweeted
Looking forward to the start of the @Fusion_Conf Recombination Mechanisms conference in Portugal. Awesome location and speakers. Best meeting of the year for sure! Thanks @SCWestLab
The West Lab retweeted
🧬 Breakthrough in DNA repair and cancer research! The team at @TheCrick has used C-Trap to explore the RAD51 paralogs which are in the same pathway with BRCA2.
The West Lab retweeted
In a collaboration between @SCWestLab and @BoultonLab, published in @Nature, researchers made key findings about a protein complex needed to repair damaged DNA and protect against cancer, which could one day help develop better targeted cancer treatments.
ow.ly/wF0w50OTZkm
The West Lab retweeted
A breakthrough in DNA repair research! @SimonBoulton and @StephenWest at @TheCrick has used #C-Trap technology to explore the BCDX2 complex. This could lead to new therapeutic strategies for diseases linked to RAD51 paralog complex mutations. Check here: go.nature.com/3PoCTzC
The West Lab retweeted
Just had amazing visits to LUMICKS, NKI, the Crick, and UCL, thanks to my exceptional LUMICKS hosts: Andrea Candelli, Jos Maas, and Nina Brett-Pitt. What an extraordinary trip! Dankjulliewel.
The West Lab retweeted
Exciting to see nucleotide excision repair down to the details. Congratulations Wei! Lesion recognition by XPC, TFIIH and XPA in DNA excision repair | Nature nature.com/articles/s41586-0…
The West Lab retweeted
Today our important study on air pollutants in the promotion of lung cancer has been published in @Nature led by @WillHilliam @LimEmilia @DrClareWeeden @SwantonLab ...Thread below🧵nature.com/articles/s41586-0…
The West Lab retweeted
Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
doi.org/10.1016/j.molcel.202…
The West Lab retweeted
Our new cryo-EM structure explains how the MRN complex can act both as DNA double-strand break sensor & DNA tethering device, read the paper here:
authors.elsevier.com/c/1gK10…
Huge thanks to all collaboration partners W.Roos, B.Steigenberger and C. Junge!
#cryoEM, #DNArepair, #MRN
The West Lab retweeted
Postdoctoral positions available in Nussenzweig lab to study mechanisms involved in DNA repair- 1st position (wet lab) focuses on using cutting-edge cellular, molecular, and genomic tools. 2nd uses computational approaches to study DNA repair.






























