@RuedaLab

Exploring nucleic acid-protein interactions at a higher resolution. Based @ImperialMed and @MRC_LMS. Opinions are my own.

 London, UK
ruedalab.org
Joined June 2014
  • Tweets529
  • Following835
  • Followers1.9K
72Media
🚨We are hiring🚨 We are looking for a chemist to join our team and synthesise novel functional ligands to interrogate chromatin dynamics! Please apply following the link below👇 DM or email me if you want more info. RT appreciated. imperial.ac.uk/jobs/descript…

Jobs

Join Imperial and be part of a world leading community of research, teaching and innovation.

imperial.ac.uk
31
3
55
18,836
As you know, these are difficult days in Israel, but the Scientific work has to continue. What started as an open discussion over Twitter/X has matured into a review of #PIFE doi.org/10.1088/2050-6120/ac… Enjoy the read

A new twist on PIFE: photoisomerisation-related fluorescence enhancement

A new twist on PIFE: photoisomerisation-related fluorescence enhancement, Ploetz, Evelyn, Ambrose, Benjamin, Barth, Anders, Börner, Richard, Erichson, Felix, Kapanidis, Achillefs N, Kim, Harold D,...

iopscience.iop.org
EitanLernerLab@eitan_lerner17 Oct 2021
Replying to @AchillesKap @majuiicb @R_H_Ebright @eLife
Nice implementation of UIFE (originally PIFE). Should we start referring to it as photo-isomerization induced fluorescence enhancement (PIFE) in general?
2
3
3
22
5,386
How can we discover better neuroactive compounds? A 4-year fully funded PhD position in my lab in London to work on one of our most interesting projects. In collaboration with @aexbrown Apply by 12 December, start in Oct 2024. findaphd.com/phds/project/ho…
10
24
9,352
David Rueda retweeted
Matt Newton@M_D_Newton2 Nov 2023
Excited to accept a position start my group @sheffielduni in @MCB_Sheffield. Huge thanks to the support from @BoultonLab, part of my lab will work closely with them using single-molecule techniques to understand telomeres. If you’re interested in working with us get in touch!
15
6
1
97
10,873
David Rueda retweeted
Matt Newton@M_D_Newton16 Oct 2023
How does the structure of target DNA affect CRISPR/Cas9 off-target activity during gene editing? We show that negative DNA supercoiling dramatically reduces Cas9 specificity. Find out more here: doi.org/10.1016/j.molcel.202… @MolecularCell @LUMICKS_nl @MRC_LMS @TheCrick @ucl
3
23
102
15,355
📢 We're now the MRC Laboratory of Medical Sciences! Going UK-wide, beyond just London. Proudly in sync with our siblings LMB, Cambridge. Check out our new look! #ForAllOfUK #MRCUpdates @MRC_LMB @UKRI_News
1
12
3
46
13,249
6 out of 8 @NobelPrize winners in Medicine, Physics, and Chemistry this year are immigrants! 🌍🏆 #DiversityInScience #NobelPrize
27
216
20
1,343
172,492
David Rueda retweeted
Taekjip Ha@taekjip4 Oct 2023
Names of purported Nobel chemistry prize winners inadvertently released reuters.com/world/names-purp…

Names of purported Nobel chemistry prize winners inadvertently released

Sweden's Royal Academy of Sciences appeared to have inadvertently published names of three scientists it said had won this year's Nobel Prize in chemistry.

reuters.com
2
2
3
3,157
🚨Final day to apply for this PhD studentship in the Cochemé lab @MRC_LMS @ImperialCollege🚨 #Redox #Ageing #Drosophila - Position available from October 2023 - Funding for 4 years, open to all applicants (UK and worldwide) - Deadline: Weds 16th August findaphd.com/phds/project/re…

Redox signalling in metabolic dysfunction and ageing at Imperial College London on FindAPhD.com

PhD Project - Redox signalling in metabolic dysfunction and ageing at Imperial College London, listed on FindAPhD.com

findaphd.com
18
25
4,535
Come work with us! We are recruiting a 2-yr postdoc/research fellow for an exciting project using single-molecule microscopy to study viral replication. closing date 17th Sept. More info & how to apply here: warwick-careers.tal.net/vx/l…
3
58
2
66
14,514
Besides BRCA2 directly binding to RPA-ssDNA, we also observed BRCA2 molecules moving along the dsDNA arms! Some of them were even able to reach the gap edge and nucleate RAD51. We calculated BRCA2 diffusion rates using MSD analysis w/ help from @arthur_pol in @RuedaLab. (6/10)
1
3
15
2,277
I'm recruiting a Senior Bioinformatician to join the @MRC_LMS Bioinformatics Facility. New building, new HPC system, new start! Know your way around *seq workflows, like Nextflow, love reproducible science ... get in touch! #Bioinformatics #jobs #London
2
22
3
27
10,272
nytimes.com/2023/07/13/scien… The passing of a pioneer.

Evelyn M. Witkin, Who Discovered How DNA Repairs Itself, Dies at 102 (Published 2023)

Her findings led to breakthroughs in the treatment of cancer and in the understanding of the mechanics of evolution.

nytimes.com
1
29
1
64
11,245
Thanks to Jane Dyson, @LabMaillard, and @RuedaLab, as well as @ckinzthompson and all the other contributing speakers for an AMAZING Proteins in Motion session on Day 3 of #PS37!
1
4
25
2,819
David Rueda retweeted
NHS Million
@NHSMillion3 Jul 2023
If everyone who has been grateful for the NHS over the past 75 years followed and retweeted we’d reach a million by midnight. Please take just two seconds to show you care.
205
11,076
257
12,395
1,084,226
David Rueda retweeted
Taekjip Ha@taekjip1 Jul 2023
Cold Spring Harbor Lab: Where White People Talk About DNA.
Jonathan Eisen
@phylogenomics1 Jul 2023
Yuck. Cold Spring Harbor Lab meeting "celebrating" 50 years of recombinant DNA is a #manel #YAMMM With a history of issues in sexism (e.g. Watson) at CSHL this is sad. And bonus featuring Lander w/ his own history of issues as session chair & panel discussion leader
image shows lists of people for this meeting with yellow and green highlighting being used for people inferred to be male or female (from information on their web sites). Shows session chairs 12:1 M:F, Panel Leaders 4:0 M:F and Speakers 47:8 M:F.

ALT image shows lists of people for this meeting with yellow and green highlighting being used for people inferred to be male or female (from information on their web sites). Shows session chairs 12:1 M:F, Panel Leaders 4:0 M:F and Speakers 47:8 M:F.

13
80
25,899
This is beautiful. Making one protein, from one mRNA, takes minutes. This method images single mRNAs as they are translated by ribosomes. And can do it for >1 hour. Translation is start-stop; not continuous. (mRNAs = red; translation sites = green). cell.com/molecular-cell/full…
10
213
9
1,023
168,777
David Rueda retweeted
Taekjip Ha@taekjip14 Jun 2023
Look at this awesome processivity of chromatin remodeling enzymes! Green for nucleosomes and red for remodellers (RSC & ISW2). Note that we had to strobe green excitation for Cy3 due to its rapid photobleaching whereas JFX554 (@rhodamine110) survives the entire episode.
bioRxiv@biorxivpreprint14 Jun 2023
Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers biorxiv.org/cgi/content/shor… #bioRxiv
3
15
86
17,038
David Rueda retweeted
Taekjip Ha@taekjip10 Jun 2023
Single-molecule characterization of target search dynamics of DNA-binding proteins in DNA-condensed droplets academic.oup.com/nar/article…
1
32
1
150
28,300
Come and join the @MRC_LMS as a Senior HPC Engineer! We're recruiting someone to come and make their mark on our brand new cluster - it's a clean slate! - and help us to build out our scientific computing provisions. mrc.tal.net/vx/lang-en-GB/mo… #HPC #Bioinformatics
13
1
13
3,980
Load more