@RuedaLab

Exploring nucleic acid-protein interactions at a higher resolution. Based @ImperialMed and @MRC_LMS. Opinions are my own.

 London, UK
ruedalab.org
Joined June 2014
  • Tweets529
  • Following835
  • Followers1.9K
72Media
Winter is coming... Fancy some single-molecule science combined with winter sports? Send your abstracts for the 3rd SMB Les Houches 2024 at smbleshouches.com Abstract selections will begin on 2nd Oct. 2023 @NynkeDekkerLab @LUMICKS_nl @PI_Physik_Inst @MadCityLabs1
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🚨We are hiring🚨 We are looking for a chemist to join our team and synthesise novel functional ligands to interrogate chromatin dynamics! Please apply following the link below👇 DM or email me if you want more info. RT appreciated. imperial.ac.uk/jobs/descript…

Jobs

Join Imperial and be part of a world leading community of research, teaching and innovation.

imperial.ac.uk
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As you know, these are difficult days in Israel, but the Scientific work has to continue. What started as an open discussion over Twitter/X has matured into a review of #PIFE doi.org/10.1088/2050-6120/ac… Enjoy the read

A new twist on PIFE: photoisomerisation-related fluorescence enhancement

A new twist on PIFE: photoisomerisation-related fluorescence enhancement, Ploetz, Evelyn, Ambrose, Benjamin, Barth, Anders, Börner, Richard, Erichson, Felix, Kapanidis, Achillefs N, Kim, Harold D,...

iopscience.iop.org
EitanLernerLab@eitan_lerner17 Oct 2021
Replying to @AchillesKap @majuiicb @R_H_Ebright @eLife
Nice implementation of UIFE (originally PIFE). Should we start referring to it as photo-isomerization induced fluorescence enhancement (PIFE) in general?
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How can we discover better neuroactive compounds? A 4-year fully funded PhD position in my lab in London to work on one of our most interesting projects. In collaboration with @aexbrown Apply by 12 December, start in Oct 2024. findaphd.com/phds/project/ho…
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David Rueda retweeted
Matt Newton@M_D_Newton2 Nov 2023
Excited to accept a position start my group @sheffielduni in @MCB_Sheffield. Huge thanks to the support from @BoultonLab, part of my lab will work closely with them using single-molecule techniques to understand telomeres. If you’re interested in working with us get in touch!
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Matt Newton@M_D_Newton16 Oct 2023
How does the structure of target DNA affect CRISPR/Cas9 off-target activity during gene editing? We show that negative DNA supercoiling dramatically reduces Cas9 specificity. Find out more here: doi.org/10.1016/j.molcel.202… @MolecularCell @LUMICKS_nl @MRC_LMS @TheCrick @ucl
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📢 We're now the MRC Laboratory of Medical Sciences! Going UK-wide, beyond just London. Proudly in sync with our siblings LMB, Cambridge. Check out our new look! #ForAllOfUK #MRCUpdates @MRC_LMB @UKRI_News
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6 out of 8 @NobelPrize winners in Medicine, Physics, and Chemistry this year are immigrants! 🌍🏆 #DiversityInScience #NobelPrize
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Taekjip Ha@taekjip4 Oct 2023
Names of purported Nobel chemistry prize winners inadvertently released reuters.com/world/names-purp…

Names of purported Nobel chemistry prize winners inadvertently released

Sweden's Royal Academy of Sciences appeared to have inadvertently published names of three scientists it said had won this year's Nobel Prize in chemistry.

reuters.com
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🚨Final day to apply for this PhD studentship in the Cochemé lab @MRC_LMS @ImperialCollege🚨 #Redox #Ageing #Drosophila - Position available from October 2023 - Funding for 4 years, open to all applicants (UK and worldwide) - Deadline: Weds 16th August findaphd.com/phds/project/re…

Redox signalling in metabolic dysfunction and ageing at Imperial College London on FindAPhD.com

PhD Project - Redox signalling in metabolic dysfunction and ageing at Imperial College London, listed on FindAPhD.com

findaphd.com
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Come work with us! We are recruiting a 2-yr postdoc/research fellow for an exciting project using single-molecule microscopy to study viral replication. closing date 17th Sept. More info & how to apply here: warwick-careers.tal.net/vx/l…
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Besides BRCA2 directly binding to RPA-ssDNA, we also observed BRCA2 molecules moving along the dsDNA arms! Some of them were even able to reach the gap edge and nucleate RAD51. We calculated BRCA2 diffusion rates using MSD analysis w/ help from @arthur_pol in @RuedaLab. (6/10)
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I'm recruiting a Senior Bioinformatician to join the @MRC_LMS Bioinformatics Facility. New building, new HPC system, new start! Know your way around *seq workflows, like Nextflow, love reproducible science ... get in touch! #Bioinformatics #jobs #London
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nytimes.com/2023/07/13/scien… The passing of a pioneer.

Evelyn M. Witkin, Who Discovered How DNA Repairs Itself, Dies at 102 (Published 2023)

Her findings led to breakthroughs in the treatment of cancer and in the understanding of the mechanics of evolution.

nytimes.com
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Thanks to Jane Dyson, @LabMaillard, and @RuedaLab, as well as @ckinzthompson and all the other contributing speakers for an AMAZING Proteins in Motion session on Day 3 of #PS37!
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NHS Million
@NHSMillion3 Jul 2023
If everyone who has been grateful for the NHS over the past 75 years followed and retweeted we’d reach a million by midnight. Please take just two seconds to show you care.
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Taekjip Ha@taekjip1 Jul 2023
Cold Spring Harbor Lab: Where White People Talk About DNA.
Jonathan Eisen
@phylogenomics1 Jul 2023
Yuck. Cold Spring Harbor Lab meeting "celebrating" 50 years of recombinant DNA is a #manel #YAMMM With a history of issues in sexism (e.g. Watson) at CSHL this is sad. And bonus featuring Lander w/ his own history of issues as session chair & panel discussion leader
image shows lists of people for this meeting with yellow and green highlighting being used for people inferred to be male or female (from information on their web sites). Shows session chairs 12:1 M:F, Panel Leaders 4:0 M:F and Speakers 47:8 M:F.

ALT image shows lists of people for this meeting with yellow and green highlighting being used for people inferred to be male or female (from information on their web sites). Shows session chairs 12:1 M:F, Panel Leaders 4:0 M:F and Speakers 47:8 M:F.

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Great science and great fun! Single molecule and DNA Repair, a great combo!
This Post is from an account that no longer exists. Learn more
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We are excited to announce the 2023 Next Generation Biophysics Symposium #NGBS2023 in person and virtually at the @MRC_LMB (27 Sept). Registration is now open here: www3.mrc-lmb.cam.ac.uk/sites… A great lineup of speakers! @MRC_LMB @ASTRAZENECAUK @imperialcollege @MRC_LMS
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This is beautiful. Making one protein, from one mRNA, takes minutes. This method images single mRNAs as they are translated by ribosomes. And can do it for >1 hour. Translation is start-stop; not continuous. (mRNAs = red; translation sites = green). cell.com/molecular-cell/full…
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