@RFledrich

Professor of Neuroanatomy @UniLeipzig. Interested in myelin disorders and regeneration. Find me there: @rfledrich@mstdn.science

 Leipzig
fledrich-lab.de
Joined June 2018
  • Tweets152
  • Following355
  • Followers362
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Excited to share the latest study on peripheral nerve repair by the Stassart/Fledrich lab! See how Schwann cells communicate with adipocytes to adjust their metabolism for successful regeneration. sciencedirect.com/science/ar…
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Dear fellow scientists, please come to Bluesky. It’s a beautiful place medpagetoday.com/special-rep…

Physicians Flock to Bluesky, Hoping to Leave X Behind

Many compare it to the early days of Twitter

medpagetoday.com
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Thrilled that the DFG will fund our #NeuroTune graduate school in Leipzig with €5.7M for 5 tandem projects creating over 40 PhD positions. The Stassart/Fledrich lab is proud to host two projects, exploring adaptive myelination in diverse contexts. tiny.cc/3fyvzz
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Robert Fledrich retweeted
Julia Edgar@JuliaEdgar13 Jun 2024
A myelinic channel system for organelle transport to the glial-axonal junction biorxiv.org/content/10.1101/… Thanks to all co-authors on and off X @KlausNave @werner_hauke @DrChapple @tabifromengland @Lina_Komarek @ColinPhD @RebeccaSmithPhD @MacpEuan

A myelinic channel system for motor-driven organelle transport

Myelin sheaths comprise compacted layers of oligodendroglial membrane wrapped spirally around axons. Each sheath, if imagined unwrapped, has a cytoplasm-filled space at its perimeter, linking it to...

biorxiv.org
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A beautiful study showing how PMP22 affects the lipid metabolism of Schwann cells in CMT1A.
Robert Prior@Rob_Prior199116 May 2024
I'm very proud that my main study from my PhD is finally out in the journal Brain! This was a huge collaborative project that took several years but I'm happy with the result!
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Robert Fledrich retweeted
Doris Krauter@DorisKrauter23 Feb 2024
Happy to share that my PhD project found a home with @EmboMolMed! We pharmacologically and genetically modified aberrant myelin growth in rodent models of PMP22 gene dosage diseases. Details below 🧵
EMBO Mol. Medicine@EmboMolMed21 Feb 2024
Targeting PI3K/Akt/mTOR signaling in rodent models of #PMP22 gene-dosage diseases. By D. Krauter, M.W. Sereda & colleagues @mpi_nat #PeripheralNeuropathies 🗞️doi.org/10.1038/s44321-023-0…
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Robert Fledrich retweeted
Tim Czopka Lab@Czopka_Lab19 Feb 2024
We are looking for a postdoc to investigate behavioural & functional correlates in zebrafish with mutations in autism genes. Great opportunity to develop a new research direction towards studying the role of glia in neurodevelopmental disorders. Please RT elxw.fa.em3.oraclecloud.com/…
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Happy to be part of this nice review in Cold Spring Harbor Perspectives in Biology with @ruth_stassart and Alison Lloyd cshperspectives.cshlp.org/co… @isabial_iis @NeuroAlc
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With the passing of Laura Feltri we lost a valued colleague who made incredible contributions to PNS research and beyond. She leaves behind a legacy that will be remembered. My deepest condolences to her family and friends.
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Robert Fledrich retweeted
Myelin Lab@MyelinLab20 Dec 2023
🚨We are hiring at the postdoctoral level. 🚨 RT very much appreciated!🤗
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Injury to peripheral #nerves in the body can result in pain and movement disorders. Scientists at #UniLeipzig have recently investigated how damaged nerves can regenerate better. Fatty tissue supports the healing process. #Medicine @RFledrich uni-leipzig.de/en/newsdetail…
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New! Online now: Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration dlvr.it/Sz4qhM
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Acute nerve injury triggers leptin receptor expression by Schwann cells. Leptin released from adipose tissue then stimulates mitochondrial respiration and myelin autophagy in Schwann cells to promote nerve repair.
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Great job @vks24865, Vlad and Nele! Big thanks to @DoctorPAF , @pepegosaelx , @ClaraMutschler, @annaslbch, @emh_es, @TheresaKungl, @KlausNave, @ost_mario and everybody involved!
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So yes, our paper is out! nature.com/articles/s41593-0… Here's how the story unfolded - thread below🧵👇
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New study on multiple sclerosis: Myelin may be detrimental to nerve fibres. Joint research by #UniLeipzig and @mpi_nat. @RFledrich uni-leipzig.de/en/newsdetail…
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Myelin turns into a risk factor for axons in #MultipleSclerosis. Team work by Stassart/Fledrich and @KlausNave labs. High five to 1st authors @marboschqueralt and Erik Schäffner, thx to @JuliaEdgar1 , @HAL4K, @TingSun_MPINAT and everyone who contributed! nature.com/articles/s41593-0…

Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease

Nature Neuroscience - Myelin is widely believed to protect axons from damage in multiple sclerosis. The authors challenge this view and find that myelin insulation renders axons more vulnerable to...

nature.com
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Robert Fledrich retweeted
Katrin Franke
@kfrankelab19 May 2023
Do you agree that animal research is essential in #Biology & #MedicalResearch? 📢The EU will be discussing a complete ban of animal research - Please support this initiative pro animal research in Europe & spread the word 🙏 braincouncil.eu/pledge-for-s…

Support Pledge for Science calling for the prioritisation of brain research & innovation in the EU

Support Pledge for Science calling for the prioritisation of brain research & innovation in the EU

braincouncil.eu
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Robert Fledrich retweeted
MeijerLab@LabMeijer3 Apr 2023
Delighted to see our work highlighted on the cover of JCB. What a great celebration of a brilliant PhD thesis by our talented Nina Kozar-Gillan. @ninakozar et al @JCellBiol (bit.ly/3Kjmslg) @EdinUniNeuro
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Happy to share great work from @DoctorPAF lab, thanks to the wonderful work of @shaline_v, @ClaraMutschler and our lab @MyelinAlicante. Thanks also to @MonkLab1, Robin, Roger, Benjamin and especially @Lab_Coleman for their support. doi.org/10.3389/fncel.2023.1…
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