
Pieter Goossens lab at the Maastricht University, #macrophage #inflammation #atherosclerosis
Maastricht, The Netherlands
Joined March 2009
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Pieter Goossens lab retweeted
Introducing our short talk speakers at the #IMMA Conference!
We’re delighted to welcome our speakers later this year and look forward to hearing their presentations.
Thinking of joining us? As well as hearing from our invited and short talk speakers, this conference will provide great opportunities to connect with all #IMMA attendees opening numerous doors for new collaborations and valueable feedback.
Click here to view our full conference speaker list ➡️ bit.ly/4bPvKCR
Pieter Goossens lab retweeted
What happens when intraplaque hemorrhage 🩸 resolves in atherosclerosis?
Right, iron 🔵 accumulates in the plaque.
In our newest preprint, we define iron deposition as a post-IPH phase in human athero.
biorxiv.org/content/10.64898…
@PiGoossensLab @CARIMMaastricht @Hartstichting
Pieter Goossens lab retweeted
Thrilled to coordinate SHE-HEALS. We’ll study how perimenopause and early menopause shape heart disease risk and test whether earlier prevention can stop silent Atherosclerosis before symptoms begin. @Cambridge_Uni @UniMelb @Cambridgecardio @HLRI_Cambridge @parcc_inserm
🚨BIG NEWS: Global research network to launch SHE‑HEALS study with US $10m from the GCRFF – aiming to advance our understanding of how menopause shapes heart health.🔗Read more: gcrff.org/news-she-heals #internationalresearchchallenge #globalcollaboration #womenscvdhealth
Pieter Goossens lab retweeted
Interested in research on cell-cell junctions and vascular biology? We are recruiting a PhD student!
werkenbij.amsterdamumc.org/e…
Pieter Goossens lab retweeted
Come and visit my poster #75 today at the @EuMacDcSoc #EMDS2024 meeting. We are presenting our recent work on #DC heterogeneity in #melanoma draining lymph nodes #SLN
Pieter Goossens lab retweeted
The MIRACLE DN officially kicked off with a successful meeting in Amsterdam! Partners, doctoral candidates, and experts came together to launch the next phase of research into cardiometabolic diseases.
🔗 Read the full recap here: miracle-dn.eu/news-and-media
Pieter Goossens lab retweeted
🔁 Super exciting to see this collaboration take off! 🚀 Amazing work from @BelaWieland, @pigoossenslab and @SarrazinSand studying #macrophage behavior in #atherosclerosis
🔬🧫 Can’t wait to follow the progress on this #CVD research! 💥 #TeamScience
🚀 The last few weeks we've been teaming up with @BelaWieland from @PiGoossensLab
to set up functional assays in vitro, studying our favorite cells’ behavior in atherosclerosis context!
🔬🧫 Get ready for exciting #macrophage 🧡 #CVD research! 💥
@SiewekeLab @CIML_Immunology
Pieter Goossens lab retweeted
🚀 The last few weeks we've been teaming up with @BelaWieland from @PiGoossensLab
to set up functional assays in vitro, studying our favorite cells’ behavior in atherosclerosis context!
🔬🧫 Get ready for exciting #macrophage 🧡 #CVD research! 💥
@SiewekeLab @CIML_Immunology
Pieter Goossens lab retweeted
Macrophage and DC enthusiasts, you don't want to miss this extraordinary meeting co-organized with @SylviaKnapp_Lab, @FGinhoux and @deVisserKarin
Pieter Goossens lab retweeted
#thesisdefence Tomorrow, Daniëlle Kerkhofs will defend the thesis 'Inflammatory cells and blood-brain barrier leakage in cerebral small vessel diseases' at 10:00h @MaastrichtU
📺youtube.com/live/UtTUnbsQOHs…
#phdlife @S_Foulquier
Pieter Goossens lab retweeted
8 hour time-restricted eating linked to 91% higher risk of cardiovascular death? 🫀
Really?! Not so "fast" ...🤔
Upon popular request, I'm covering this news release.
👉 1) This is not in reference to a published paper.
Rather, these were "preliminary" results presented at an AHA epidemiology conference. The paper that these data may yield is not published, so informed commentary is necessarily limited.
👉2) The article notes, "Previous research has found that time-restricted eating improves several cardiometabolic health measures, such as blood pressure, blood glucose and cholesterol levels." They also provide no biologically plausible rationale for the results.
👉3A) The results themselves were based on self-report...
This doesn't invalidate the data itself (I'm not against questionnaires); however, in the context of findings that are at odds with other data (as noted above) and absence of presented biological plausibility, and high probability of reporter bias (e.g. perhaps people with higher risk factors and more clinical clinical 'concern' are more likely to report trying 16-8), I would take this with a grain of salt (but not too many grains... because that will raise your blood pressure... with TRF helps, btw).
3B) "Time-restricted eating was determined on the basis of just two days of dietary intake”
3C) Also "the nutrient quality" was not assessed
4) Not all elements of the news coverage were clear/consistent. E.g. "Among people with existing cardiovascular disease, an eating duration of no less than 8 but less than 10 hours per day was also associated with a 66% higher risk of death from heart disease or stroke." Is this saying in those with CVD <8 was okay, but <10 was bad? That's odd and a little "sus" (as the kids say)
And, in closing, it's worth noting the news article itself says "The Association makes no representation or guarantee as to their [the data's] accuracy or reliability."
I'll continue to skip breakfast as it suits me.
You do you.
cc' @MatthewNehsMD @ChrisPalmerMD @drjasonfung @bigfatsurprise @DoctorTro @KenDBerryMD @AdrianSotoMota anything to add?
You gonna' pick up some Cheerios for your heart?
Pieter Goossens lab retweeted
The Huveneers lab has a postdoc vacancy in Vascular Cell Biology !!! @amsterdamumc
Apply here: werkenbij.amsterdamumc.org/e…
Please spread the word
Pieter Goossens lab retweeted
Spatial metabolomics shows LPA(18:1) and LPC(18:0) accumulation in advanced plaques with reflection of CV risk in plasma @SluimerJudith @PiGoossensLab @BelaWieland @galdamiz65 ahajrnls.org/3Opyv1J
Pieter Goossens lab retweeted
We're looking for a postdoc to join our group to take on projects studying macrophages in atherosclerosis pathogenesis. If you're interested in learning intravital 2-photon or 3D tissue-clearing imaging approaches, please reach out and apply. ❄️🔬🧬🧫
hr.myu.umn.edu/jobs/ext/3593…
Pieter Goossens lab retweeted
4y post-doc opportunity @CARIMMaastricht ! Research field open. Would you like to build your own research line in the field of vascular #dementia #cSVD? Join our gliovascular group. DM for more info. #glia #Microscopy #microcirculation #neuroscience #stroke #pharmacology 🧵
Pieter Goossens lab retweeted
📢 Join our team! 🧬
2 open positions:
1️⃣ Post-Doc Researcher
2️⃣ Bioinformatician
#macrophages->gene regulation, long-term epigenetic changes. Impact on regeneration, aging, and cancer.
Unravel the secrets of self-renewal, activation, aging, and "trained immunity." 🧪💡
Pieter Goossens lab retweeted
"These methods can order a set of individual cells along a path, and assign a pseudotime value to each cell that represents where the cell is along that path. This can be a starting point for further analysis to determine gene expression programs driving cell phenotypes."
Pieter Goossens lab retweeted
🎉Our Cancer immune archetype perspective is on @NatureRevCancer's July cover!. We're seeking a #postdoc to unravel the cellular networks and gene programs behind these archetypes. If you're fueled by passion for immunology and oncology 👉t.ly/0C3bB Please RT🙏

































