Stephan Huveneers, Associate Professor at Amsterdam UMC, University of Amsterdam, Vascular Microenvironment and Integrity https://xitter.cf/t.co/3LmTDdONqK
Amsterdam, The Netherlands
Joined November 2017
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A junctional PACSIN2/EHD4/MICAL-L1 complex coordinates VE-cadherin trafficking for endothelial migration and… disq.us/t/3wt3h0a
Huveneers Lab retweeted
On our September cover (hubs.la/Q04wKzY90): Immunofuorescence image of the anterior part of a #zebrafsh embryo showing the blood vasculature in magenta and endothelial nuclei in cyan. From Janssen et al. @Huveneers_Lab: hubs.la/Q04wKzYK0
Huveneers Lab retweeted
Vera Janssen, Ana Angulo-Urarte, Stephan Huveneers et al. show that nanoscale membrane curvatures at asymmetric endothelial cell–cell junctions serve as a scaffold to recruit BAR proteins, including BIN1 and SNX9, during collective migration. hubs.la/Q04qSY_v0
Huveneers Lab retweeted
3D super-res microscopy reveals ultrastructure of asymmetric adherens junctions between leader & follower cells in angiogenesis – BIN1 & SNX9 are regulators
📹 Vera Janssen et al University of Amsterdam in @JCellBiol
➡️ bpod.org.uk/archive/2026/8/2
Huveneers Lab retweeted
A big thank you to everyone who joined us at the EMBO Workshop 'Building networks: engineering in vascular biology' at EMBL Barcelona last week. It was a fantastic few days of inspiring science, lively discussions, new collaborations, and a great reminder of how rapidly the vascular biology and bioengineering communities are evolving together. 🧬🫀
Special thanks to all organisers and speakers for making the meeting such a success 👏🏼
Keynote speakers
Holger Gerhardt, Max Delbrück Center, Germany
Matthias Lütolf, EPFL, Switzerland
Maike Sander, Max Delbrück Center, Germany
Scientific organisers
Katie Bentley, The Francis Crick Institute, UK
Christopher Chen, Boston University, USA
Kristina Haase, EMBL Barcelona, Spain
Stephan Huveneers, Amsterdam AMC, The Netherlands
See you all next time!
#EMBOBuildNetworks #VascularBiology #Bioengineering @EMBO @EMBOevents
Huveneers Lab retweeted
Welcome to Day 1 of 'Building networks: engineering in vascular biology' taking place at EMBL Barcelona! ☀️🌴 #EMBOBuildNetworks
We're kicking off at 9:30, and we're excited for three inspiring days of cutting-edge science, insightful talks, lively discussions, and engaging poster sessions bringing together the vascular biology and engineering communities from around the world.🫀🔬
Huveneers Lab retweeted
.@Huveneers_Lab highlights recent work from Mayo et al. (hubs.la/Q04f1ClR0) identifying Scribble as a regulator of endothelial #AdherensJunctions during #angiogenesis. hubs.la/Q04f2dnL0
#Adhesion #Cytoskeleton #Development
News from the lab! We identify the Calcineurin-NFAT-DSCR1.4 signaling pathway as a druggable driver of capillary malformations caused by the GNAQ p.R183Q mutation, which is associated with port-wine stains and Sturge-Weber syndrome.
🔗 Publication: rdcu.be/e2gRC
The article also includes a full phosphoproteomic dataset mapping downstream signaling of the GNAQ p.R183Q mutation in endothelial cells.
🔗 Proteomic data available at: ebi.ac.uk/pride/archive/proj…
With Tong Xu, Vera Janssen and Nathalie Reinhard as shared first authors, we would like to thank everyone who contributed!
#Angiogenesis #VascularBiology #Endothelial #PortWineStains #SturgeWeberSyndrome #AmsterdamUMC
Huveneers Lab retweeted
🔬 Join us in Barcelona to meet researchers working at the intersection of engineering and vascular biology and discover cutting-edge techniques in spatial omics, advanced imaging, and AI. #EMBOBuildNetworks @events.embl.org
13 – 15 May 2026 Register: s.embl.org/evb26-01-bl
Interested in research on cell-cell junctions and vascular biology? We are recruiting a PhD student!
werkenbij.amsterdamumc.org/e…
Huveneers Lab retweeted
The exciting, complete VAC 2025 program is now online! vacure-conference.net/index.…
Don't wait to register! vacure-conference.net/
@vascern @hevas_nl @VASCAPA @CMTCOVM @ISSVA_org @PTENFoundation @LGDA_EU @LGDAlliance @AtavistikBio @PalvellaTX
Huveneers Lab retweeted
VE-cadherin RGD motifs are dispensable for cell-cell junctions, endothelial barrier function and leukocyte extravasation biorxiv.org/cgi/content/shor… #biorxiv_cellbio
Huveneers Lab retweeted
#EVBOSeminarSeries Moderated by Sine Karaman. Speakers:
Rene Hägerling, Jurjan Aman and @chiara_testini. ⏰When: Tuesday, 10th December 2024, EU time (2PM UK). Place: online. See you there! For registration evbo.org
Interested in sonoporation as drug delivery approach in blood vessels? Mind the underlying endothelial cytoskeleton! Its organisation influences the endothelial response to ultrasound-activated microbubbles. New collaborative publication out led by Kooiman's lab from Erasmus MC
Ultrasound-activated microbubbles mediate F-actin disruptions and endothelial gap formation during sonoporation.
| Klazina Kooiman @ErasmusMC | @CRSBeNeLuxFr
#microbubble #ultrasound #sonoporation
doi.org/10.1016/j.jconrel.20…
Huveneers Lab retweeted
In their #OpenAccess Review, @vera_janssen1 and @Huveneers_lab @amsterdamumc explore how recent advances in fluorescence & electron microscopy along with biosensors & optogenetic tools have updated long-standing models of cell–cell adhesion.
journals.biologists.com/jcs/…
ALT Updated models of junctional cytoskeletal force systems and maturing epithelial junctions. (A) A model of the transition of a nascent ZA and desmosome plaque into mature junctions. (B) A model of the balanced cytoskeletal pushing and pulling forces that organize AJ adhesion and mechanical coupling. (C) A controlled imbalance in pushing and pulling forces induces the formation of asymmetric junctions in collective cell migration.
Huveneers Lab retweeted
And it’s out - our special issue on ‘Imaging Cell Architecture and Dynamics’! Huge thanks to everyone - authors, reviewers and editors (@EM_STP and @guijacquemet) - who contributed! 🙌
#imaging #cellbiology #microscopy
Our Special Issue on Imaging Cell Architecture and Dynamics is now complete.
You can explore our ToC here: journals.biologists.com/jcs/…
‘Breaking symmetry’ from @AntaraC9 was the winning image from our cover competition with @focalplane_jcs. The image is a MEF labelled with phalloidin (green), acetylated tubulin antibody (magenta) & DAPI (blue).
ALT Journal of Cell Science cover showing a MEF labelled with phalloidin (actin – green), acetylated tubulin antibody (magenta) and DAPI (DNA – blue). Special Issue on Imaging Cell Architecture and Dynamics Guest Editors: Lucy Collinson and Guillaume Jacquemet The Company of Biologists logo